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147. Wire-guided cannulation over a pancreatic stent versus double guidewire technique in patients with difficult biliary cannulation.
作者: Min Jae Yang.;Jae Chul Hwang.;Byung Moo Yoo.;Jin Hong Kim.;Hyoung-Kyu Ryu.;Soon Sun Kim.;Joon Koo Kang.;Min Kyeong Kim.
来源: BMC Gastroenterol. 2015年15卷150页
In cases of difficult bile duct cannulation, the use of wire-guided cannulation over a pancreatic stent (WGC-PS) or the double guidewire technique (DGT) may facilitate biliary cannulation. The aim of this study was to compare the outcomes of WGC-PS and DGT in patients with difficult biliary cannulation.
153. Histone deacetylase (HDAC)-1, -2, -4 and -6 expression in human pancreatic adenocarcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients' survival.
作者: Constantinos Giaginis.;Christos Damaskos.;Ioannis Koutsounas.;Adamantia Zizi-Serbetzoglou.;Nicolaos Tsoukalas.;Efstratios Patsouris.;Gregorios Kouraklis.;Stamatios Theocharis.
来源: BMC Gastroenterol. 2015年15卷148页
Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The present study aimed to evaluate the clinical significance of HDAC-1, -2, -4 and -6 protein expression in pancreatic adenocarcinoma.
154. A case report of successful treatment of pyoderma gangrenosum in a patient with autoimmune hepatitis, and review of the literature.
作者: Theodoros Androutsakos.;Paraskevas Stamopoulos.;Kiriaki Aroni.;Gregorios Hatzis.
来源: BMC Gastroenterol. 2015年15卷149页
Pyoderma Gangrenosum (PG) is a cutaneous condition, its diagnosis suggested by the presence of a painful cutaneous ulcer showing rapid progression. Pyoderma gangrenosum is associated with a concomitant systemic disease in 50 to 70 % of cases, including inflammatory bowel disease (IBD), rheumatoid arthritis, and lymphoproliferative disorders. Although PG has also been reported with viral hepatitis, it is rarely associated with autoimmune hepatitis.
156. The usefulness of C-reactive protein and neutrophil-to-lymphocyte ratio for predicting the outcome in hospitalized patients with liver cirrhosis.
作者: Jung Hyun Kwon.;Jeong Won Jang.;Young Woon Kim.;Sung Won Lee.;Soon Woo Nam.;Dongwook Jaegal.;Seungok Lee.;Si Hyun Bae.
来源: BMC Gastroenterol. 2015年15卷146页
The role of clinical parameters such as systemic inflammatory response syndrome (SIRS) criteria in predicting the infection remains unclear in cirrhosis patients. The aim was to evaluate the usefulness of inflammatory markers including C-reactive protein (CRP) and the neutrophil-to-lymphocyte ratio (NLR) for diagnosis of infection and predicting the outcomes in hospitalized cirrhotic patients.
157. Reduced lymphocyte count as an early marker for predicting infected pancreatic necrosis.
作者: Xiao Shen.;Jing Sun.;Lu Ke.;Lei Zou.;Baiqiang Li.;Zhihui Tong.;Weiqin Li.;Ning Li.;Jieshou Li.
来源: BMC Gastroenterol. 2015年15卷147页
Early occurrence of immunosuppression is a risk factor for infected pancreatic necrosis (IPN) in the patients with acute pancreatitis (AP). However, current measures for the immune systems are too cumbersome and not widely available. Significantly decreased lymphocyte count has been shown in patients with severe but not mild type of AP. Whereas, the correlation between the absolute lymphocyte count and IPN is still unknown. We conduct this study to reveal the exact relationship between early lymphocyte count and the development of IPN in the population of AP patients.
158. Effectiveness of Simeprevir Plus Sofosbuvir, With or Without Ribavirin, in Real-World Patients With HCV Genotype 1 Infection.
作者: Mark S Sulkowski.;Hugo E Vargas.;Adrian M Di Bisceglie.;Alexander Kuo.;K Rajender Reddy.;Joseph K Lim.;Giuseppe Morelli.;Jama M Darling.;Jordan J Feld.;Robert S Brown.;Lynn M Frazier.;Thomas G Stewart.;Michael W Fried.;David R Nelson.;Ira M Jacobson.; .
来源: Gastroenterology. 2016年150卷2期419-29页
The interferon-free regimen of simeprevir plus sofosbuvir was recommended by professional guidelines for certain patients with hepatitis C virus (HCV) genotype 1 infection based on the findings of a phase 2 trial. We aimed to evaluate the safety and efficacy of this regimen in clinical practice settings in North America.
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