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8621. Complement activation in patients with systemic lupus erythematosus without nephritis.
作者: T E Mollnes.;H J Haga.;J G Brun.;E W Nielsen.;A Sjöholm.;G Sturfeldt.;U Mårtensson.;K Bergh.;O P Rekvig.
来源: Rheumatology (Oxford). 1999年38卷10期933-40页
To study the association between disease activity and complement activation prospectively in patients with systemic lupus erythematosus (SLE).
8622. A review of gastrointestinal manifestations of systemic lupus erythematosus.
In this review, we analyse critically the effects of systemic lupus erythematosus (SLE) on the gastrointestinal (GI) tract from mouth to anus, attempting to distinguish the features that are most likely to be due to therapy. GI manifestations of SLE include mouth ulcers, dysphagia, anorexia, nausea, vomiting, haemorrhage and abdominal pain. GI vasculitis is usually accompanied by evidence of active disease in other organs. Early recognition of the significance of these symptoms offers the best opportunity to improve the symptoms and to aid long-term survival.
8631. Directions in rheumatology: past, present and future. Report of a conference to celebrate the 50th anniversary of the Oliver Bird Fund held at Churchill College Cambridge, 24-26 September 1998.8632. A Fas promoter polymorphism at position -670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes.
作者: G Coakley.;N Manolios.;T P Loughran.;G S Panayi.;J S Lanchbury.
来源: Rheumatology (Oxford). 1999年38卷9期883-6页
We examined whether there are associations between a polymorphism in the Fas promoter, recently found to be associated with rheumatoid arthritis (RA), and Felty's syndrome or large granular lymphocyte (LGL) leukaemia.
8633. Defining disease activity in ankylosing spondylitis: is a combination of variables (Bath Ankylosing Spondylitis Disease Activity Index) an appropriate instrument?
作者: A Calin.;J P Nakache.;A Gueguen.;H Zeidler.;H Mielants.;M Dougados.
来源: Rheumatology (Oxford). 1999年38卷9期878-82页
Disease activity has been defined using a self-administered instrument, focusing on fatigue, axial pain, peripheral pain, enthesopathy and morning stiffness [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)]. This validated instrument is simple and takes 40 s to complete, but whether the index is an accurate expression of the component parts, or whether additional weighting would enhance its efficacy, is unclear.
8634. Generic and condition-specific outcome measures for people with osteoarthritis of the knee.
作者: J E Brazier.;R Harper.;J Munro.;S J Walters.;M L Snaith.
来源: Rheumatology (Oxford). 1999年38卷9期870-7页
The aims of this study were to evaluate two condition-specific and two generic health status questionnaires for measuring health-related quality of life in patients with osteoarthritis (OA) of the knee, and to offer guidance to clinicians and researchers in choosing between them.
8635. The effect of acupuncture on patients with rheumatoid arthritis: a randomized, placebo-controlled cross-over study.
作者: J David.;S Townsend.;R Sathanathan.;S Kriss.;C J Doré.
来源: Rheumatology (Oxford). 1999年38卷9期864-9页
Acupuncture is commonly used by patients with chronic painful musculoskeletal disorders. There are, however, few well-designed studies of its efficacy. This paper describes a randomized placebo-controlled cross-over design to evaluate acupuncture as a useful treatment adjunct in the management of patients with rheumatoid arthritis (RA).
8636. Establishment of nurse-like stromal cells from bone marrow of patients with rheumatoid arthritis: indication of characteristic bone marrow microenvironment in patients with rheumatoid arthritis.
作者: T Tomita.;E Takeuchi.;T Toyosaki-Maeda.;H Oku.;M Kaneko.;H Takano.;K Sugamoto.;K Ohzono.;R Suzuki.;T Ochi.
来源: Rheumatology (Oxford). 1999年38卷9期854-63页
To investigate the microenvironment of bone marrow (BM) of patients with rheumatoid arthritis (RA).
8637. Splenectomy for refractory thrombocytopenia in the antiphospholipid syndrome.
Thrombocytopenia, usually mild, is one of the clinical criteria of the antiphospholipid syndrome (APS). Rarely, this disorder requires treatment and, due to the shared characteristics with idiopathic thrombocytopenic purpura (ITP), similar rules are followed. We report our experience in patients who required splenectomy after being refractory to steroids and immunosuppressive therapy.
8638. Relationship between soluble markers of immune activation and bone turnover in post-menopausal women with rheumatoid arthritis.
Regarding interactions between pro-inflammatory cytokines and bone metabolism in rheumatoid arthritis (RA), we investigated the relationship between the serum levels of interleukin (IL)-1beta, IL-6, soluble interleukin-2 receptor (sIL-2r), C-reactive protein (CRP), the vitamin D metabolites 25-hydroxyvitamin D3 (25OHD3) and 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], intact parathyroid hormone (iPTH) as well as serum and urinary parameters of bone turnover in 74 post-menopausal women with RA.
8639. Changes in serum chondroitin sulphate epitopes 3-B-3 and 7-D-4 in early rheumatoid arthritis.
作者: J Middleton.;S White.;E Parry.;C Jackson.;J Dixey.;B Ashton.
来源: Rheumatology (Oxford). 1999年38卷9期837-40页
The aims of the present rheumatoid arthritis (RA) study were (1) to examine the levels of serum 3-B-3 and 7-D-4 to find out whether they are different from controls, (2) to find out whether the concentrations of these epitopes change with disease duration in early RA and (3) whether the serum concentrations of 3-B-3 and 7-D-4 in early RA are prognostic for subsequent disease progression.
8640. Studying patients with inflammatory back pain and arthritis of the lower limbs clinically and by magnetic resonance imaging: many, but not all patients with sacroiliitis have spondyloarthropathy.
作者: J Brandt.;M Bollow.;J Häberle.;M Rudwaleit.;U Eggens.;A Distler.;J Sieper.;J Braun.
来源: Rheumatology (Oxford). 1999年38卷9期831-6页
Clinical and magnetic resonance imaging (MRI) data of 170 consecutive patients with inflammatory back pain (IBP) and/or oligoarthritis of the lower limbs were evaluated in a retrospective study. The aim was to determine the frequency of sacroiliitis and spondyloarthropathy (SpA) in this population, and to assess the significance of HLA B27 measurements for diagnosis in early disease.
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