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8602. Th1-type cytokine mRNA in rheumatoid arthritis mononuclear cells induced by streptococcal pyrogenic exotoxin A.
作者: K Szczepanska.;Z Chrzanowska-Lightowlers.;B A Degnan.;A G Diamond.;T Robson.;A Ryzewska.;J A Goodacre.
来源: Rheumatology (Oxford). 1999年38卷10期1022-4页 8607. Articular hypermobility in Icelandic 12-year-olds.
To examine the prevalence of articular hypermobility and its relationship to musculoskeletal pain in Icelandic 12-yr-olds, and to obtain baseline data for a prospective study on the subject.
8608. Musculoskeletal conditions in children attending two Togolese hospitals.
作者: M Mijiyawa.;O Oniankitan.;K Attoh-Mensah.;A Tékou.;E K Lawson.;G B Priuli.;J K Assimadi.
来源: Rheumatology (Oxford). 1999年38卷10期1010-3页
A retrospective study was conducted in order to point out the different kinds of musculoskeletal conditions observed in children attending two Togolese hospitals.
8609. Long-lasting remission and successful treatment of acquired factor VIII inhibitors using cyclophosphamide in a patient with systemic lupus erythematosus.
作者: F Trotta.;G Bajocchi.;R La Corte.;S Moratelli.;L Y Sun.
来源: Rheumatology (Oxford). 1999年38卷10期1007-9页
Acquired deficiency of clotting factor VIII (FVIII) is a rare bleeding diathesis seldom encountered in systemic lupus erythematosus (SLE). Reduction of FVIII activity by autoantibodies can cause potentially life-threatening situations. Herein, an SLE patient with a positive lupus anticoagulant (LAC) test who abruptly developed metrorrhagia 4 yr after diagnosis is reported. Coagulation tests revealed FVIII activity reduced to 3% and a prolonged aPTT. FVIII inhibitor(s) were found to be as high as 3.0 Bethesda Units. Plasmapheresis, immunoglobulins, prednisolone and FVIII plasma concentrates induced the cessation of metrorrhagia, but the clotting tests were barely improved. One month later, extensive ecchymosis appeared and worsened, despite re-administration of the previous therapy. Pulse cyclophosphamide followed by oral administration was then started with normalization of coagulation parameters and long-lasting disease remission.
8610. Seasonal variation in the onset of acute microcrystalline arthritis.
作者: M Gallerani.;M Govoni.;M Mucinelli.;M Bigoni.;F Trotta.;R Manfredini.
来源: Rheumatology (Oxford). 1999年38卷10期1003-6页
To determine whether acute attacks of uric acid and calcium pyrophosphate microcrystalline arthritis show a seasonal variation and, if so, to verify whether the distribution of single episodes shows a rhythmic circannual pattern.
8611. Effect of methotrexate on blood purine and pyrimidine levels in patients with rheumatoid arthritis.
作者: Z Smoleńska.;Z Kaznowska.;D Zarówny.;H A Simmonds.;R T Smoleński.
来源: Rheumatology (Oxford). 1999年38卷10期997-1002页
The mechanism of anti-inflammatory effects of methotrexate (MTX) at low dose may relate to a decrease in availability of the purine precursor or it may depend on accumulation of 5-aminoimidazole-4-carboxamide (AICAR) and the anti-inflammatory nucleoside adenosine. The aim of this study was to evaluate the possible mechanism of action by analysis of changes in blood concentrations of purine and pyrimidine metabolites during MTX treatment.
8612. Cyclosporin A and iloprost treatment of systemic sclerosis: clinical results and interleukin-6 serum changes after 12 months of therapy.
作者: G Filaci.;M Cutolo.;M Scudeletti.;C Castagneto.;L Derchi.;R Gianrossi.;F Ropolo.;P Zentilin.;A Sulli.;G Murdaca.;M Ghio.;F Indiveri.;F Puppo.
来源: Rheumatology (Oxford). 1999年38卷10期992-6页
The main aim was to analyse the long-term therapeutic effects on systemic sclerosis (SSc) patients of treatment with either (i) iloprost alone or (ii) low-dose oral cyclosporin A (CyA) associated with iloprost. A secondary aim was to analyse interleukin-6 (IL-6) serum levels in SSc patients before and after 1 yr of treatment.
8613. Pro-inflammatory effects of the aminobisphosphonate ibandronate in vitro and in vivo.
To investigate the effects of the aminobisphosphonate, ibandronate, on the course of joint inflammation in rat antigen-induced arthritis (AIA) and the release of pro-inflammatory cytokines in partially purified human peripheral blood mononuclear cells (PBMC).
8614. Rheumatic disorders developed after hepatitis B vaccination.
作者: J F Maillefert.;J Sibilia.;E Toussirot.;E Vignon.;J P Eschard.;B Lorcerie.;R Juvin.;N Parchin-Geneste.;C Piroth.;D Wendling.;J L Kuntz.;C Tavernier.;P Gaudin.
来源: Rheumatology (Oxford). 1999年38卷10期978-83页
To obtain an overview of rheumatic disorders occurring after hepatitis B vaccination.
8615. Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial.
To compare the effectiveness of a steroid injection (25 mg/ml prednisolone acetate) with a local anaesthetic control in the treatment of heel pain and to determine any advantage for patients' comfort of using a posterior tibial nerve block to anesthetize the heel prior to infiltration.
8617. The effects of dothiepin on subjects with rheumatoid arthritis and depression.
作者: G Ash.;C M Dickens.;F H Creed.;M I Jayson.;B Tomenson.
来源: Rheumatology (Oxford). 1999年38卷10期959-67页
The relative importance of direct analgesic and antidepressant effects of antidepressant drugs in rheumatoid arthritis (RA) is not clear.
8618. Systemic lupus erythematosus: clinical features in patients with a disease duration of over 10 years, first evaluation.
作者: A J Swaak.;H G van den Brink.;R J Smeenk.;K Manger.;J R Kalden.;S Tosi.;A Marchesoni.;Z Domljan.;B Rozman.;D Logar.;G Pokorny.;L Kovacs.;A Kovacs.;P G Vlachoyiannopoulos.;H M Moutsopoulos.;H Chwalinska-Sadowska.;B Dratwianka.;E Kiss.;N Cikes.;A Branimir.;M Schneider.;R Fischer.;S Bombardieri.;M Mosca.;J S Smolen.
来源: Rheumatology (Oxford). 1999年38卷10期953-8页
Most information available about the disease course of patients with systemic lupus erythematosus (SLE) is restricted to the first 5 yr after disease onset. Data about the disease course 10 yr after disease onset are rare. The aim of this multicentre study was to describe the outcome of SLE patients with a disease duration of >10 yr.
8619. Changes in plasma free fatty acid concentrations in rheumatoid arthritis patients during fasting and their effects upon T-lymphocyte proliferation.
作者: D A Fraser.;J Thoen.;A C Rustan.;O Førre.;J Kjeldsen-Kragh.
来源: Rheumatology (Oxford). 1999年38卷10期948-52页
To measure whether changes in the concentrations of circulating free fatty acids (FFAs) after a 7 day fast in rheumatoid arthritis (RA) patients would inhibit in vitro T-lymphocyte proliferation.
8620. Reliability and sensitivity to change of a simplification of the Sharp/van der Heijde radiological assessment in rheumatoid arthritis.
作者: D van der Heijde.;T Dankert.;F Nieman.;R Rau.;M Boers.
来源: Rheumatology (Oxford). 1999年38卷10期941-7页
To determine the reliability and sensitivity to change of a simplified radiological scoring method [simple erosion narrowing score (SENS)] for rheumatoid arthritis (RA). SENS was compared to the Sharp/van der Heijde score (SHS) as a gold standard.
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