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7981. Serum interleukin-15 is elevated in systemic lupus erythematosus.
作者: M Aringer.;G H Stummvoll.;G Steiner.;M Köller.;C W Steiner.;E Höfler.;H Hiesberger.;J S Smolen.;W B Graninger.
来源: Rheumatology (Oxford). 2001年40卷8期876-81页
To investigate if interleukin-15 (IL-15) (rather than IL-2) is increased in systemic lupus erythematosus (SLE) and might be responsible for immunological abnormalities of SLE such as the increased lymphocytic expression of Bcl-2 and CD25.
7982. Systemic lupus erythematosus and rheumatoid arthritis patients differ from healthy controls in their cytokine pattern after stress exposure.
作者: R Jacobs.;C R Pawlak.;E Mikeska.;D Meyer-Olson.;M Martin.;C J Heijnen.;M Schedlowski.;R E Schmidt.
来源: Rheumatology (Oxford). 2001年40卷8期868-75页
To study whether patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) differ from healthy individuals in their immune responses to acute psychological stress.
7983. Comparison of renal disease severity and outcome in patients with primary antiphospholipid syndrome, antiphospholipid syndrome secondary to systemic lupus erythematosus (SLE) and SLE alone.
To ascertain the clinical presentation, histopathology and outcome of renal involvement in patients with primary antiphospholipid syndrome (PAPS), antiphospholipid syndrome secondary to systemic lupus erythematosus (SAPS) and systemic lupus erythematosus alone.
7984. Pain referral from the sternoclavicular joint: a study in normal volunteers.
The sternoclavicular joint (SCJ) is commonly affected by rheumatological conditions. Case reports suggest that it may refer pain to distant areas, potentially leading to delays in diagnosis and inappropriately targeted investigations. Therefore, we studied the patterns of pain referral from the SCJ of nine healthy volunteers.
7985. Monoclonal anti-double stranded DNA antibody is a leucocyte-binding protein to up-regulate interleukin-8 gene expression and elicit apoptosis of normal human polymorphonuclear neutrophils.
作者: S C Hsieh.;K H Sun.;C Y Tsai.;Y Y Tsai.;S T Tsai.;D F Huang.;S H Han.;H S Yu.;C L Yu.
来源: Rheumatology (Oxford). 2001年40卷8期851-8页
To determine whether anti-double stranded DNA (anti-dsDNA) autoantibody could bind and affect the functions of normal human polymorphonuclear neutrophils (PMN).
7986. Responsiveness of the Cochin rheumatoid hand disability scale after surgery.
作者: M M Lefevre-Colau.;S Poiraudeau.;J Fermanian.;F Etchepare.;J Y Alnot.;D Le Viet.;C Leclercq.;C Oberlin.;F Bargy.;M Revel.
来源: Rheumatology (Oxford). 2001年40卷8期843-50页
To assess the responsiveness of the Cochin functional disability scale for the rheumatoid hand after surgery.
7993. Haemophagocytic syndrome in a systemic lupus erythematosus patient with antiphospholipid antibodies.
作者: M Nawata.;J Suzuki.;K Ikeda.;S Ando.;M Koike.;I Sekigawa.;N Iida.;R Wada.;M Matsumoto.;K Oshimi.;H Hashimoto.
来源: Rheumatology (Oxford). 2001年40卷7期828-9页 7995. Renal type AA amyloidosis associated with rheumatoid arthritis: a cohort study showing improved survival on treatment with pulse cyclophosphamide.
To determine the incidence of renal AA amyloidosis and its association with rheumatoid arthritis (RA) in a cohort of all renal biopsies at one referral hospital and to measure the effect of a monthly pulse of cyclophosphamide on renal function and survival in these RA patients.
7996. Leg ulcers in patients with rheumatoid arthritis--a prospective study of aetiology, wound healing and pain reduction after pinch grafting.
To study the aetiology of leg ulcers in patients with rheumatoid arthritis (RA) and to study healing and pain relief after pinch grafting.
7997. Factors predictive of subsequent deterioration in rheumatoid cervical myelopathy.
To identify the features of rheumatoid cervical spine disease associated with deterioration resulting in the need for surgical intervention or death.
7998. Autoantibodies to a 68/48 kDa protein in chronic fatigue syndrome and primary fibromyalgia: a possible marker for hypersomnia and cognitive disorders.
作者: M Nishikai.;S Tomomatsu.;R W Hankins.;S Takagi.;K Miyachi.;S Kosaka.;K Akiya.
来源: Rheumatology (Oxford). 2001年40卷7期806-10页
To identify antinuclear antibodies (ANA) specific for chronic fatigue syndrome (CFS), and in related conditions such as fibromyalgia (FM) or psychiatric disorders.
7999. Indirect evidence of intra-articular immunoglobulin G synthesis in patients with Chlamydia trachomatis reactive arthritis.
To investigate whether B-cell stimulation occurs in joints of Chlamydia trachomatis reactive arthritis patients by comparing the immunoglobulin G (IgG) anti-C. trachomatis antibody responses in serum and synovial fluid (SF).
8000. Inhibition of neutrophil responses by cyclosporin A. An insight into molecular mechanisms.
作者: S Spisani.;E Fabbri.;M Muccinelli.;A Cariani.;L Barbin.;F Trotta.;L Dovigo.
来源: Rheumatology (Oxford). 2001年40卷7期794-800页
Cyclosporin A (CsA) is an effective agent in rheumatoid arthritis (RA), slowing joint damage progression. Its therapeutic effect on T lymphocytes has been studied extensively, but there is little information available about neutrophils, the cells responsible for a substantial proportion of inflammation. A study was performed to investigate the in vitro effects of CsA on neutrophil functions triggered by several agonists and determine whether the drug could counteract the binding of formyl-methionyl-leucyl-phenylalanine (fMLP) to its receptor and/or modulate changes in the intracellular Ca(2+) concentration ([Ca(2+)]i).
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