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7684. The synergistic value of focus score and IgA% score of sublabial salivary gland biopsy for the accuracy of the diagnosis of Sjögren's syndrome: a 10-year comparison.
作者: M M Zandbelt.;J R M Wentink.;P C M de Wilde.;P A van Damme.;L B A van de Putte.;F H J van den Hoogen.
来源: Rheumatology (Oxford). 2002年41卷7期819-23页
Increasing the accuracy of the diagnosis of Sjögren's syndrome (SS) by placing emphasis on objective findings such as the presence of anti-Ro and anti-La autoantibodies and abnormal salivary gland tissue (SGT) histology is a current issue. In order to obtain optimal disease sensitivity and specificity of SGT findings, histological and immunohistological SGT examinations were compared. The first describes the extent of the lymphocytic infiltrate as a focus score (LFS), whereas the latter describes the composition of the infiltrate as a percentage of IgA-containing plasma cells (IgA%).
7685. Rapid diagnosis of inflammatory synovial fluid with reagent strips.
作者: P Ravaud.;C Hudry.;B Giraudeau.;B Weill.;M Dougados.
来源: Rheumatology (Oxford). 2002年41卷7期815-8页
To determine the usefulness of reagent test strips for screening inflammatory synovial fluid (SF).
7686. Diagnostic tests for rheumatoid arthritis: comparison of anti-cyclic citrullinated peptide antibodies, anti-keratin antibodies and IgM rheumatoid factors.
作者: S Bas.;T V Perneger.;M Seitz.;J-M Tiercy.;P Roux-Lombard.;P A Guerne.
来源: Rheumatology (Oxford). 2002年41卷7期809-14页
To examine the value of anti-cyclic citrullinated peptide (anti-CCP) antibodies, anti-keratin antibodies (AKA) and immunoglobulin M rheumatoid factors (IgM RF) in discriminating between rheumatoid arthritis (RA) and other rheumatic diseases, and to determine whether the clinical manifestations or severity of erosions in RA are associated with anti-CCP positivity.
7687. Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage.
This study evaluated the in vitro effect of the selective cyclooxygenase-2 (COX) inhibitor celecoxib on cartilage matrix turnover under normal and inflammatory conditions.
7688. The prevalence of rheumatoid arthritis in the United Kingdom: new estimates for a new century.
作者: D Symmons.;G Turner.;R Webb.;P Asten.;E Barrett.;M Lunt.;D Scott.;A Silman.
来源: Rheumatology (Oxford). 2002年41卷7期793-800页
It is 40 yr since the last age- and sex-specific estimates of the prevalence of rheumatoid arthritis (RA) for the UK were published. Since then the classification criteria for RA have been revised and there has been evidence of a fall in the incidence of RA, especially in women.
7689. Role of cholecystokinin-8 in nerve growth factor and nerve growth factor mRNA expression in carrageenan-induced joint inflammation in adult rats.
The aim of our study was to investigate the role of cholecystokinin-8 (CCK-8), which is able to induce the synthesis of nerve growth factor (NGF), in the joint inflammation of carrageenan-injected rats.
7690. Risk of myelotoxicity with intravenous cyclophosphamide in patients with systemic lupus erythematosus.
作者: G E Katsifis.;A G Tzioufas.;P G Vlachoyiannopoulos.;M Voulgarelis.;H M Moutsopoulos.;J P A Ioannidis.
来源: Rheumatology (Oxford). 2002年41卷7期780-6页
To determine the incidence of serious myelotoxicity from intravenous cyclophosphamide (IC) in systemic lupus erythematosus (SLE).
7691. Dynamics of mycobacterial HSP65-induced T-cell cytokine expression during oral tolerance induction in adjuvant arthritis.
作者: P M Cobelens.;A Kavelaars.;R van der Zee.;W van Eden.;C J Heijnen.
来源: Rheumatology (Oxford). 2002年41卷7期775-9页
To investigate whether oral administration of mycobacterial heat-shock protein 65 (HSP65) during adjuvant arthritis (AA) induces regulatory cells and cytokines.
7692. Total costs and predictors of costs in individuals with early inflammatory polyarthritis: a community-based prospective study.
作者: N J Cooper.;M Mugford.;D P M Symmons.;E M Barrett.;D G I Scott.
来源: Rheumatology (Oxford). 2002年41卷7期767-74页
To estimate the health service, non-health service and total costs and predictors of costs in individuals with early inflammatory polyarthritis (IP).
7693. A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients.
作者: J Gu.;E Märker-Hermann.;D Baeten.;W C Tsai.;D Gladman.;M Xiong.;H Deister.;J G Kuipers.;F Huang.;Y W Song.;W Maksymowych.;J Kalsi.;M Bannai.;N Seta.;M Rihl.;L J Crofford.;E Veys.;F De Keyser.;D T Y Yu.
来源: Rheumatology (Oxford). 2002年41卷7期759-66页
To identify genes which are more highly expressed in the peripheral blood mononuclear cells (PBMC) of patients with spondyloarthropathy (SpA), rheumatoid arthritis (RA) and psoriatic arthritis (PsA), in comparison to normal subjects.
7694. Measured ambulation and self-reported health status following total joint replacement for the osteoarthritic knee.
To quantify the increase in ambulation produced by total knee replacement for osteoarthritis (OA) of the knee and to compare this with questionnaire-derived data.
7695. Illiteracy in rheumatoid arthritis patients as determined by the Rapid Estimate of Adult Literacy in Medicine (REALM) score.
To determine the prevalence of illiteracy in a cohort of rheumatoid arthritis (RA) patients and the impact of illiteracy on disease severity and function.
7696. Methotrexate in the treatment of rheumatoid arthritis. II. In vivo effects on bone mineral density.
作者: N J Minaur.;D Kounali.;S Vedi.;J E Compston.;J N Beresford.;A K Bhalla.
来源: Rheumatology (Oxford). 2002年41卷7期741-9页
To determine the effect of methotrexate (MTX) on bone mineral density (BMD) in rheumatoid arthritis (RA).
7697. Methotrexate in the treatment of rheumatoid arthritis. I. In vitro effects on cells of the osteoblast lineage.
作者: N J Minaur.;C Jefferiss.;A K Bhalla.;J N Beresford.
来源: Rheumatology (Oxford). 2002年41卷7期735-40页
Low-dose methotrexate (MTX) is often used in the treatment of rheumatoid arthritis (RA). To be effective, treatment must be long-term, and there are concerns that MTX may impair bone formation in a population already predisposed to osteoporosis. The purpose of this investigation was to determine the direct effects of MTX at clinically relevant doses on the growth and differentiation of human cells of the osteoblast (bone-forming) lineage.
7698. Superior mesenteric artery blood flow in systemic sclerosis patients.
作者: F Quarto Di Palo.;R Rivolta.;V Berruti.;M Caronni.;S Bazzi.;R Scorza.
来源: Rheumatology (Oxford). 2002年41卷7期730-4页
Intestinal involvement is frequently observed in systemic sclerosis (SSc) and is associated with malnutrition and a decreased survival rate. Vascular lesions are claimed to underlie and precede these changes. The aim of this study was to establish whether a reduced mesenteric blood flow was present in SSc patients with no signs or symptoms of small bowel involvement.
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