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7562. Remitting seronegative symmetrical synovitis with pitting oedema as the first manifestation of psoriatic arthropathy.
作者: L Díez-Porres.;S Muñoz-Fernández.;P Aguado.;M Alonso.;E Martín-Mola.
来源: Rheumatology (Oxford). 2002年41卷11期1333-5页 7566. Assessment of specialist registrars in rheumatology: experience of an objective structured clinical examination (OSCE).
Assessment of higher medical trainees (specialist registrars) in rheumatology is an important challenge facing the rheumatology community, particularly with the advent of the implemention of the changes recommended by the Calman Report in the UK. So far there has been remarkably little work in this area. Our aim was to implement and evaluate an objective structured clinical examination (OSCE) for rheumatology specialist registrars (SpRs).
7567. Recurrent focal myositis of the peroneal muscles.
作者: K Kisielinski.;O Miltner.;B Sellhaus.;S Krüger.;H Goost.;C H Siebert.
来源: Rheumatology (Oxford). 2002年41卷11期1318-22页
Recurrent focal myositis is a rare entity and can be difficult to diagnose and treat. A long-term follow-up and diagnostic evaluation was carried out in a patient who presented with ankle stiffness secondary to a painful mass within the calf. This process was diagnosed as focal myositis of the peroneal muscles, which recurred over a period of 7 yr. A review of the literature regarding focal myositis, treatment options and a successful conservative therapy regimen, as an alternative to a surgical protocol, are presented. After making the diagnosis with the help of a muscle biopsy, long-term therapy should be considered. Conservative treatment of focal myositis with anti-inflammatory drugs and physical therapy can be successful but recurrence may occur if the medical treatment is interrupted.
7568. A critical evaluation of commercial immunoassays for antineutrophil cytoplasmic antibodies directed against proteinase 3 and myeloperoxidase in Wegener's granulomatosis and microscopic polyangiitis.
To evaluate the performance of 11 commercial enzyme-linked immunosorbent assay (ELISA) kits for the detection of antineutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3 (PR3) and myeloperoxidase (MPO) in patients with Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA).
7569. Outcome of neuropsychiatric systemic lupus erythematosus within a defined Swedish population: increased morbidity but low mortality.
作者: A Jönsen.;A A Bengtsson.;O Nived.;B Ryberg.;G Sturfelt.
来源: Rheumatology (Oxford). 2002年41卷11期1308-12页
To investigate the outcome of neuropsychiatric involvement in systemic lupus erythematosus patients (NPSLE) recruited from a defined population.
7570. Effectiveness of TNF-alpha blockade with infliximab in refractory Wegener's granulomatosis.
作者: P Lamprecht.;J Voswinkel.;T Lilienthal.;B Nolle.;M Heller.;W L Gross.;A Gause.
来源: Rheumatology (Oxford). 2002年41卷11期1303-7页
To study the effect of the chimeric monoclonal anti-tumour necrosis factor alpha (TNF-alpha) antibody infliximab in the induction of remission in six patients refractory to standard treatment with cyclophosphamide and corticosteroids. In four patients, other measures for treating refractory Wegener's granulomatosis (WG) that have been advocated previously, i.e. intensified cyclophosphamide therapy and additional intravenous immunoglobulin, were ineffective.
7571. Disease-specific, patient-assessed measures of health outcome in ankylosing spondylitis: reliability, validity and responsiveness.
作者: K L Haywood.;A M Garratt.;K Jordan.;K Dziedzic.;P T Dawes.
来源: Rheumatology (Oxford). 2002年41卷11期1295-302页
To assess the acceptability and measurement properties of four ankylosing spondylitis (AS)-specific, patient-assessed measures of health outcome: AS Quality of Life Questionnaire (ASQoL), Bath AS Disease Activity Index (BASDAI), the Body Chart and the Revised Leeds Disability Questionnaire (RLDQ).
7572. Churg-Strauss syndrome: clinical and serological features of 19 patients from a single Italian centre.
作者: A Della Rossa.;C Baldini.;A Tavoni.;A Tognetti.;D Neglia.;G Sambuceti.;R Puccini.;C Colangelo.;S Bombardieri.
来源: Rheumatology (Oxford). 2002年41卷11期1286-94页
Churg-Strauss syndrome is a rare multisystem vasculitis of unknown aetiology. Due to the rarity of the disease, few single-centre case series have been described. The aim of this study was to evaluate a small series from a single Italian centre in order to describe the clinical features of the disease, the treatment and long-term follow-up.
7573. Efficacy of infliximab in refractory ankylosing spondylitis: results of a six-month open-label study.
作者: M Breban.;E Vignon.;P Claudepierre.;V Devauchelle.;D Wendling.;E Lespessailles.;L Euller-Ziegler.;J Sibilia.;A Perdriger.;M Mezières.;C Alexandre.;M Dougados.
来源: Rheumatology (Oxford). 2002年41卷11期1280-5页
To evaluate the efficacy and safety of a loading regimen of the anti-tumour necrosis factor alpha (TNF-alpha) antibody infliximab in predominantly axial severe ankylosing spondylitis (AS).
7574. Pharmacogenetics in rheumatology: the prospects and limitations of an emerging field.
To review the fundamental concepts of pharmacogenetics and analyse how the broad principles of this rapidly emerging field may influence the treatment of rheumatic disease in future.
7575. Clinical significance of serum surfactant protein D (SP-D) in patients with polymyositis/dermatomyositis: correlation with interstitial lung disease.
作者: H Ihn.;Y Asano.;M Kubo.;K Yamane.;M Jinnin.;N Yazawa.;M Fujimoto.;K Tamaki.
来源: Rheumatology (Oxford). 2002年41卷11期1268-72页
To determine the clinical significance of serum surfactant protein D (SP-D) levels in patients with polymyositis/dermatomyositis (PM/DM).
7576. Age and waiting time as predictors of outcome after total hip replacement for osteoarthritis.
To investigate in a prospective study the relationship between age, pre-operative status, waiting time and post-operative outcome in patients assigned for unilateral total hip replacement (THR) due to osteoarthritis (OA).
7577. Synovial fluid from patients with rheumatoid arthritis inhibits neutrophil apoptosis: role of adenosine and proinflammatory cytokines.
作者: L Ottonello.;M Cutolo.;G Frumento.;N Arduino.;M Bertolotto.;M Mancini.;E Sottofattori.;F Dallegri.
来源: Rheumatology (Oxford). 2002年41卷11期1249-60页
In synovial fluid (SF) from patients with rheumatoid arthritis (RA), neutrophils are exposed to proinflammatory mediators endowed with either anti-apoptotic or pro-apoptotic properties. We investigated neutrophil apoptosis in the presence of SF from 11 RA patients.
7578. Comparison of two hyaluronan drugs and placebo in patients with knee osteoarthritis. A controlled, randomized, double-blind, parallel-design multicentre study.
To compare the efficacy and safety of intra-articular injections of two different hyaluronan preparations and placebo in patients with knee osteoarthritis.
7579. Osteoclast formation and activity in the pathogenesis of osteoporosis in rheumatoid arthritis.
Rheumatoid arthritis (RA) is often complicated by generalized osteopenia due to increased bone resorption by osteoclasts. We analysed a number of cellular and humoral factors that influence osteoclast formation from circulating precursors in RA patients.
7580. Reviews of acupuncture for chronic neck pain: pitfalls in conducting systematic reviews.
This paper examines some of the problems specifically associated with conducting research into acupuncture and how this can lead to further problems with subsequent systematic reviews. Studies for the treatment of chronic neck pain have been used as examples of how presented information can be misleading to an acupuncture-naive reader and how researchers must be sensitive to these problems when compiling their inclusion and exclusion criteria. The problems associated with scoring trials are discussed and further work to increase the scope of scoring mechanisms is recommended in order to produce meaningful systematic reviews in the future.
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