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7541. Allergic vasculitis associated with celecoxib.7543. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: predictive factors for mood and pain.
To examine the predictive factors for anxiety, depression and pain in adults with juvenile idiopathic arthritis (JIA).
7544. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: social function, relationships and sexual activity.
To examine social function, relationships and sexual activity in adults with juvenile idiopathic arthritis (JIA).
7545. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: education and employment.
To examine the levels of education and employment in adults with juvenile idiopathic arthritis (JIA) compared with their siblings and national figures.
7546. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: functional outcome.
To examine the clinical and functional outcome of adults with juvenile idiopathic arthritis (JIA) using the recent World Health Organization/International League Against Rheumatism (ILAR) classification.
7548. Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis.
作者: M van der Paardt.;J B A Crusius.;M A García-González.;P Baudoin.;P J Kostense.;B Z Alizadeh.;B A C Dijkmans.;A S Peña.;I E van der Horst-Bruinsma.
来源: Rheumatology (Oxford). 2002年41卷12期1419-23页
Since ulcerative colitis and Crohn's disease, which are associated with ankylosing spondylitis (AS), have been found to be variably associated with the IL-1B and the IL-1RN genes encoding interleukin-1beta (IL-1beta) and the interleukin-1 receptor antagonist (IL-1ra), we have investigated whether these polymorphisms in IL-1B and IL-1RN are also involved in AS.
7549. Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes.
作者: F Iannone.;C De Bari.;F Dell'Accio.;M Covelli.;V Patella.;G Lo Bianco.;G Lapadula.
来源: Rheumatology (Oxford). 2002年41卷12期1413-8页
We aimed to investigate the expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) on chondrocytes from human healthy and osteoarthritic cartilage.
7550. Three-dimensional kinematics at the ankle joint complex in rheumatoid arthritis patients with painful valgus deformity of the rearfoot.
To evaluate the three-dimensional (3D) kinematics of the ankle joint complex (AJC) in rheumatoid arthritis (RA) patients with painful valgus deformity of the rearfoot.
7551. The use of the Internet as a resource for health information among patients attending a rheumatology clinic.
To determine the proportion of patients attending a rheumatology clinic who have access to a computer with Internet capabilities, to establish how often they search for health information, and how difficult or useful they find this resource.
7552. Comparison of the faecal microflora of patients with ankylosing spondylitis and controls using molecular methods of analysis.
作者: S Stebbings.;K Munro.;M A Simon.;G Tannock.;J Highton.;H Harmsen.;G Welling.;P Seksik.;J Dore.;G Grame.;A Tilsala-Timisjarvi.
来源: Rheumatology (Oxford). 2002年41卷12期1395-401页
To determine whether differences within the complex intestinal microflora can be demonstrated between patients with ankylosing spondylitis (AS) and healthy individuals.
7553. Balance impairments in individuals with symptomatic knee osteoarthritis: a comparison with matched controls using clinical tests.
作者: R S Hinman.;K L Bennell.;B R Metcalf.;K M Crossley.
来源: Rheumatology (Oxford). 2002年41卷12期1388-94页
To compare balance in individuals with symptomatic knee osteoarthritis (OA) and in age-, gender- and body-mass-matched controls using simple clinical measures.
7554. Generic measures of health-related quality of life in ankylosing spondylitis: reliability, validity and responsiveness.
To assess the acceptability and measurement properties of two generic measures of health-related quality of life (HRQL): the EuroQol and the Short Form 12-item Health Survey Questionnaire (SF-12) in ankylosing spondylitis (AS).
7555. Increased level of HLA-B27 expression in ankylosing spondylitis patients compared with healthy HLA-B27-positive subjects: a possible further susceptibility factor for the development of disease.
作者: A Cauli.;G Dessole.;M T Fiorillo.;A Vacca.;A Mameli.;P Bitti.;G Passiu.;R Sorrentino.;A Mathieu.
来源: Rheumatology (Oxford). 2002年41卷12期1375-9页
In B27 transgenic rats, susceptibility to the development of a spondyloarthropathy-like disease has been shown to correlate with the level of B27 transgene expression on lymphoid cells. The aim of this work was to study HLA-B27 molecule expression in peripheral blood mononuclear cells (PBMCs) from patients with ankylosing spondylitis (AS) and from normal controls (NC).
7556. The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses.
Therapy of rheumatoid arthritis (RA) is typically characterized by the sequential use of disease-modifying anti-rheumatic drugs (DMARDs). This study aimed to reveal treatment patterns with traditional DMARDs and their changes during the two decades before the recent introduction of new DMARDs.
7557. Clinical and serological associations of ribosomal P autoantibodies in systemic lupus erythematosus: prospective evaluation in a large cohort of Italian patients.
作者: R Gerli.;L Caponi.;A Tincani.;R Scorza.;M G Sabbadini.;M G Danieli.;V De Angelis.;M Cesarotti.;M Piccirilli.;R Quartesan.;P Moretti.;C Cantoni.;F Franceschini.;I Cavazzana.;L Origgi.;M Vanoli.;E Bozzolo.;L Ferrario.;A Padovani.;O Gambini.;L Vanzulli.;D Croce.;S Bombardieri.
来源: Rheumatology (Oxford). 2002年41卷12期1357-66页
To verify the association of ribosomal anti-P antibodies (anti-P), as detected by a sensitive ELISA, with serological findings and clinical manifestations, including neuropsychiatric involvement evaluated according to the American College of Rheumatology (ACR) nomenclature, in a large cohort of patients with systemic lupus erythematosus (SLE).
7558. Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review.
作者: T Pincus.;G Ferraccioli.;T Sokka.;A Larsen.;R Rau.;I Kushner.;F Wolfe.
来源: Rheumatology (Oxford). 2002年41卷12期1346-56页
Earlier reports, including a comprehensive 1983 review, had indicated that slowing of radiographic progression was relatively unusual in treatment of rheumatoid arthritis (RA) using traditional disease modifying anti-rheumatic drugs. However, in recent years, slowing of radiographic progression has been documented in a number of clinical trials, as well as long-term observational studies, with use of (in alphabetical order) adalimumab, anakinra, corticosteroids, cyclophosphamide, cyclosporin, etanercept, gold salts, infliximab, leflunomide, methotrexate and sulphasalazine. At this time, disease modification is a realistic goal in the clinical care of patients with RA. Documentation of improved long-term outcomes requires long-term observational data over 5-20 yr to supplement data from randomized controlled clinical trials over 6-24 months.
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