"Ann Intern Med"[journal] 检索结果

541. Antimicrobial Access in the 21st Century: Delays and Critical Shortages.

作者: Shmuel Shoham.;Annukka A R Antar.;Paul G Auwaerter.;Christine M Durand.;Mark S Sulkowski.;Deborah J Cotton.
来源: Ann Intern Med. 2016年165卷1期53-54页

542. PCSK9 Inhibitors: Lots of Work Done, Lots More to Do.

作者: Michael S Lauer.
来源: Ann Intern Med. 2016年164卷9期624-5页

543. Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review.

作者: Eliano P Navarese.;Michalina Kolodziejczak.;Dean J Kereiakes.;Udaya S Tantry.;Christopher O'Connor.;Paul A Gurbel.
来源: Ann Intern Med. 2016年164卷9期600-7页

Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) are an emerging therapy for dyslipidemia. Acute coronary events induce a dynamic increase of PCSK9 levels that may play a role in plaque vulnerability of both culprit and nonculprit coronary vessels. Growing evidence highlights a potential key role of PCSK9 antibodies in managing acute coronary syndrome. This review describes the influence of PCSK9 antibodies on plaque composition and instability, as well as the pharmacokinetic profile and the potential anti-inflammatory and antithrombotic mechanisms associated with PCSK9 inhibition that may confer benefits during the early phase of acute coronary syndrome. The authors posit a rationale for the use of PCSK9 antibodies in patients with acute coronary syndrome and highlight the need for further investigation in this area.

544. Gradual Versus Abrupt Smoking Cessation: A Randomized, Controlled Noninferiority Trial.

作者: Nicola Lindson-Hawley.;Miriam Banting.;Robert West.;Susan Michie.;Bethany Shinkins.;Paul Aveyard.
来源: Ann Intern Med. 2016年164卷9期585-92页

Most smoking cessation guidelines advise quitting abruptly. However, many quit attempts involve gradual cessation. If gradual cessation is as successful, smokers can be advised to quit either way.

545. In adults without CVD, the MESA score, including coronary artery calcium, predicted 10-y risk for CHD events.

作者: Donald A Smith.
来源: Ann Intern Med. 2016年164卷6期JC35页

546. Review: In patients with chest pain, risk scores better predict high risk for ACS than individual risk factors.

作者: Eric R Bates.
来源: Ann Intern Med. 2016年164卷6期JC34页

547. Restarting antithrombotics after GI bleeding was linked to better outcomes in patients with AF.

作者: Geoffrey D Barnes.;James D Douketis.
来源: Ann Intern Med. 2016年164卷6期JC33页

548. Review: Peripheral thermometers do not have clinically acceptable accuracy for measuring core body temperature.

作者: Harrison G Weed.
来源: Ann Intern Med. 2016年164卷6期JC32页

549. Review: PCSK9 inhibitors reduce mortality but increase neurocognitive events in hypercholesterolemia.

作者: Raul D Santos.
来源: Ann Intern Med. 2016年164卷6期JC31页

550. Review: In obstructive sleep apnea, CPAP and mandibular devices do not differ for reducing blood pressure.

作者: Ken Kunisaki.
来源: Ann Intern Med. 2016年164卷6期JC30页

551. In chronic nonspecific neck pain, adding Alexander Technique lessons or acupuncture to usual care improved pain.

作者: Michael J Baime.
来源: Ann Intern Med. 2016年164卷6期JC29页

552. TDF-FTC before and after sex reduced HIV infection but increased GI, renal events in men who have sex with men.

作者: Dennis G Maki.
来源: Ann Intern Med. 2016年164卷6期JC28页

553. Evidence-Based Guideline: ACR made 10 strong treatment recommendations for RA, but high-quality evidence was sparse.

作者: Robin Christensen.;Lawrence E Hart.
来源: Ann Intern Med. 2016年164卷6期JC27页

554. Review: Mammography screening reduces breast cancer mortality in women at average risk.

作者: Joann G Elmore.
来源: Ann Intern Med. 2016年164卷6期JC26页

555. Web Exclusives. The Consult Guys--Homans Sign: A Sign of What?

作者: Geno J Merli.;Howard H Weitz.
来源: Ann Intern Med. 2016年164卷6期CG1页

556. Breast Cancer Recommendation Statement From the U.S. Preventive Services Task Force.

来源: Ann Intern Med. 2016年164卷6期448页

557. The Integration of Care for Mental Health, Substance Abuse, and Other Behavioral Health Conditions Into Primary Care.

作者: Richard Saitz.;Sarah E Wakeman.;John F Kelly.
来源: Ann Intern Med. 2016年164卷6期447页

558. The Integration of Care for Mental Health, Substance Abuse, and Other Behavioral Health Conditions Into Primary Care.

作者: Ryan A Crowley.;Neil Kirschner.;Darilyn V Moyer.
来源: Ann Intern Med. 2016年164卷6期447-8页

559. Going Slow May Not Be Best When Quitting Smoking.

作者: Gabriela S Ferreira.;Michael B Steinberg.
来源: Ann Intern Med. 2016年164卷9期622-3页

560. Emerging Infections and Blood Safety in the 21st Century.

作者: Evan M Bloch.;Matthew S Simon.;Beth H Shaz.
来源: Ann Intern Med. 2016年165卷1期57-58页

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