525. Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes.
作者: Marco Valgimigli.;Enrico Frigoli.;Sergio Leonardi.;Martina Rothenbühler.;Andrea Gagnor.;Paolo Calabrò.;Stefano Garducci.;Paolo Rubartelli.;Carlo Briguori.;Giuseppe Andò.;Alessandra Repetto.;Ugo Limbruno.;Roberto Garbo.;Paolo Sganzerla.;Filippo Russo.;Alessandro Lupi.;Bernardo Cortese.;Arturo Ausiello.;Salvatore Ierna.;Giovanni Esposito.;Patrizia Presbitero.;Andrea Santarelli.;Gennaro Sardella.;Ferdinando Varbella.;Simone Tresoldi.;Nicoletta de Cesare.;Stefano Rigattieri.;Antonio Zingarelli.;Paolo Tosi.;Arnoud van 't Hof.;Giacomo Boccuzzi.;Elmir Omerovic.;Manel Sabaté.;Dik Heg.;Peter Jüni.;Pascal Vranckx.; .
来源: N Engl J Med. 2015年373卷11期997-1009页
Conflicting evidence exists on the efficacy and safety of bivalirudin administered as part of percutaneous coronary intervention (PCI) in patients with an acute coronary syndrome.
527. Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure.
作者: Martin R Cowie.;Holger Woehrle.;Karl Wegscheider.;Christiane Angermann.;Marie-Pia d'Ortho.;Erland Erdmann.;Patrick Levy.;Anita K Simonds.;Virend K Somers.;Faiez Zannad.;Helmut Teschler.
来源: N Engl J Med. 2015年373卷12期1095-105页
Central sleep apnea is associated with poor prognosis and death in patients with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to treat central sleep apnea by delivering servo-controlled inspiratory pressure support on top of expiratory positive airway pressure. We investigated the effects of adaptive servo-ventilation in patients who had heart failure with reduced ejection fraction and predominantly central sleep apnea.
528. Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.
作者: Carlos A Morillo.;Jose Antonio Marin-Neto.;Alvaro Avezum.;Sergio Sosa-Estani.;Anis Rassi.;Fernando Rosas.;Erick Villena.;Roberto Quiroz.;Rina Bonilla.;Constança Britto.;Felipe Guhl.;Elsa Velazquez.;Laura Bonilla.;Brandi Meeks.;Purnima Rao-Melacini.;Janice Pogue.;Antonio Mattos.;Janis Lazdins.;Anis Rassi.;Stuart J Connolly.;Salim Yusuf.; .
来源: N Engl J Med. 2015年373卷14期1295-306页
The role of trypanocidal therapy in patients with established Chagas' cardiomyopathy is unproven.
530. Percutaneous Implantation of an Entirely Intracardiac Leadless Pacemaker.
作者: Vivek Y Reddy.;Derek V Exner.;Daniel J Cantillon.;Rahul Doshi.;T Jared Bunch.;Gery F Tomassoni.;Paul A Friedman.;N A Mark Estes.;John Ip.;Imran Niazi.;Kenneth Plunkitt.;Rajesh Banker.;James Porterfield.;James E Ip.;Srinivas R Dukkipati.; .
来源: N Engl J Med. 2015年373卷12期1125-35页
Cardiac pacemakers are limited by device-related complications, notably infection and problems related to pacemaker leads. We studied a miniaturized, fully self-contained leadless pacemaker that is nonsurgically implanted in the right ventricle with the use of a catheter.
532. Cyclosporine before PCI in Patients with Acute Myocardial Infarction.
作者: Thien-Tri Cung.;Olivier Morel.;Guillaume Cayla.;Gilles Rioufol.;David Garcia-Dorado.;Denis Angoulvant.;Eric Bonnefoy-Cudraz.;Patrice Guérin.;Meier Elbaz.;Nicolas Delarche.;Pierre Coste.;Gerald Vanzetto.;Marc Metge.;Jean-François Aupetit.;Bernard Jouve.;Pascal Motreff.;Christophe Tron.;Jean-Noel Labeque.;Philippe Gabriel Steg.;Yves Cottin.;Grégoire Range.;Jérome Clerc.;Marc J Claeys.;Patrick Coussement.;Fabrice Prunier.;Frédéric Moulin.;Olivier Roth.;Loïc Belle.;Philippe Dubois.;Paul Barragan.;Martine Gilard.;Christophe Piot.;Patrice Colin.;Fabien De Poli.;Marie-Claude Morice.;Omar Ider.;Jean-Luc Dubois-Randé.;Thierry Unterseeh.;Hervé Le Breton.;Thierry Béard.;Didier Blanchard.;Gilles Grollier.;Vincent Malquarti.;Patrick Staat.;Arnaud Sudre.;Eskil Elmer.;Magnus J Hansson.;Cyrille Bergerot.;Inesse Boussaha.;Claire Jossan.;Geneviève Derumeaux.;Nathan Mewton.;Michel Ovize.
来源: N Engl J Med. 2015年373卷11期1021-31页
Experimental and clinical evidence suggests that cyclosporine may attenuate reperfusion injury and reduce myocardial infarct size. We aimed to test whether cyclosporine would improve clinical outcomes and prevent adverse left ventricular remodeling.
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