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363. Autosomal dominant familial Mediterranean fever in Northern European Caucasians associated with deletion of p.M694 residue-a case series and genetic exploration.
作者: Dorota M Rowczenio.;Daniela S Iancu.;Hadija Trojer.;Janet A Gilbertson.;Julian D Gillmore.;Ashutosh D Wechalekar.;Mehmet Tekman.;Horia C Stanescu.;Robert Kleta.;Thirusha Lane.;Philip N Hawkins.;Helen J Lachmann.
来源: Rheumatology (Oxford). 2017年56卷2期209-213页
This study was undertaken to characterize the phenotype and response to treatment in patients with autosomal dominant FMF caused by MEFV p.M694del mutation and to use haplotype reconstruction to investigate the possibility of common ancestry.
364. The effects of add-on non-invasive brain stimulation in fibromyalgia: a meta-analysis and meta-regression of randomized controlled trials.
The effects of non-invasive brain stimulation (NBS), including repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (TDCS), in treating FM remain inconclusive. The aim of this study was to investigate present evidence of using NBS as an add-on treatment in treating FM.
367. Long-term safety profile of anakinra in patients with severe cryopyrin-associated periodic syndromes.
作者: Torbjörn Kullenberg.;Malin Löfqvist.;Mika Leinonen.;Raphaela Goldbach-Mansky.;Hans Olivecrona.
来源: Rheumatology (Oxford). 2016年55卷8期1499-506页
Anakinra is approved for the treatment of RA and cryopyrin-associated periodic syndromes (CAPS). While the anakinra safety profile is well established in RA, the long-term safety profile in severe CAPS is less well documented and will therefore be discussed in this report.
368. Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species.
作者: Per Wekell.;Halla Björnsdottir.;Lena Björkman.;Martina Sundqvist.;Karin Christenson.;Veronica Osla.;Stefan Berg.;Anders Fasth.;Amanda Welin.;Johan Bylund.;Anna Karlsson.
来源: Rheumatology (Oxford). 2016年55卷8期1489-98页
We aimed to investigate if aberrant intracellular production of NADPH oxidase-derived reactive oxygen species (ROS) in neutrophils is a disease mechanism in the autoinflammatory disease SAPHO syndrome, characterized by synovitis, acne, pustulosis, hyperostosis and osteitis, as has previously been suggested based on a family with SAPHO syndrome-like disease.
369. Rituximab in the treatment of inflammatory myopathies: a review.
作者: Serena Fasano.;Patrick Gordon.;Raouf Hajji.;Esthela Loyo.;David A Isenberg.
来源: Rheumatology (Oxford). 2017年56卷1期26-36页
Several uncontrolled studies have encouraged the use of rituximab (RTX) in patients with myositis. Unfortunately, the first placebo-phase trial to assess the efficacy of RTX in refractory myositis did not show a significant difference between the two treatment groups, and doubts have been expressed about its study design. In this review we present an up-to-date overview of the reported experiences of RTX therapy in myositis. A PubMed search was performed to find all the available cases of refractory myositis patients treated with RTX up to July 2015. The following terms were assessed: inflammatory myopathies OR anti-synthetase syndrome OR polymyositis OR dermatomyositis AND RTX. A total of 48 studies were included. We identified 458 patients with myositis treated with RTX. We found a rate of response to RTX of 78.3%. RTX can play a role in the management of patients with myositis, at least in those with positive myositis-specific autoantibodies.
370. Erosive and osteoarthritic structural progression in early rheumatoid arthritis.
作者: Daniel F McWilliams.;Michelle Marshall.;Keeranur Jayakumar.;Sally Doherty.;Michael Doherty.;Weiya Zhang.;Patrick D W Kiely.;Adam Young.;David A Walsh.
来源: Rheumatology (Oxford). 2016年55卷8期1477-88页
To investigate factors associated with joint damage in early RA, and how comorbid OA might influence patient assessment and outcomes.
373. Risk of Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis treated with inhibitors of tumour necrosis factor α: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.
作者: Ellen S Bruce.;Lianne Kearsley-Fleet.;Kath D Watson.;Deborah P M Symmons.;Kimme L Hyrich.
来源: Rheumatology (Oxford). 2016年55卷7期1336-7页 374. Prediction of remission and low disease activity in disease-modifying anti-rheumatic drug-refractory patients with rheumatoid arthritis treated with golimumab.
作者: Nathan Vastesaeger.;Abraham Garcia Kutzbach.;Howard Amital.;Karel Pavelka.;María Alicia Lazaro.;Robert J Moots.;Jürgen Wollenhaupt.;Cristiano A F Zerbini.;Ingrid Louw.;Bernard Combe.;Andre Beaulieu.;Hendrik Schulze-Koops.;Bhaskar Dasgupta.;Bo Fu.;Susan Huyck.;Haoling H Weng.;Marinella Govoni.;Patrick Durez.
来源: Rheumatology (Oxford). 2016年55卷8期1466-76页
To create a tool to predict probability of remission and low disease activity (LDA) in patients with RA being considered for anti-TNF treatment in clinical practice.
375. Effect of adalimumab on the work-related outcomes scores in patients with early rheumatoid arthritis receiving methotrexate.
作者: Paul Emery.;Josef S Smolen.;Arijit Ganguli.;Sebastian Meerwein.;Yanjun Bao.;Hartmut Kupper.;Naijun Chen.;Arthur Kavanaugh.
来源: Rheumatology (Oxford). 2016年55卷8期1458-65页
To evaluate the effects of adalimumab plus MTX (ADA + MTX) vs MTX monotherapy on work-related outcomes in early RA patients with elevated risk of employment loss.
377. Cryoglobulinaemic vasculitis at diagnosis predicts mortality in primary Sjögren syndrome: analysis of 515 patients.
作者: Soledad Retamozo.;Hoda Gheitasi.;Luca Quartuccio.;Belchin Kostov.;Laura Corazza.;Albert Bové.;Antoni Sisó-Almirall.;Myriam Gandía.;Manuel Ramos-Casals.;Salvatore De Vita.;Pilar Brito-Zerón.
来源: Rheumatology (Oxford). 2016年55卷8期1443-51页
To evaluate the fulfilment of classification criteria for cryoglobulinaemic vasculitis (CV) at diagnosis in a large cohort of patients with primary SS and their correlation with poor outcomes.
378. Utility of 18F-fluoro-dexoxyglucose positron emission tomography for the diagnosis of polymyalgia rheumatica: a controlled study.
作者: Maxime Sondag.;Xavier Guillot.;Frank Verhoeven.;Oleg Blagosklonov.;Clément Prati.;Hatem Boulahdour.;Daniel Wendling.
来源: Rheumatology (Oxford). 2016年55卷8期1452-7页
To compare (18)F-fluoro-dexoxyglucose PET/CT (FDG-PET/CT) findings in patients with polymyalgia rheumatica (PMR) and controls without rheumatologic disease.
379. Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome.
作者: Andreas Barratt-Due.;Yngvar Fløisand.;Hilde L Orrem.;Ann K Kvam.;Pål A Holme.;Grethe Bergseth.;Geir E Tjønnfjord.;Tom E Mollnes.
来源: Rheumatology (Oxford). 2016年55卷7期1337-9页 |