当前位置: 首页 >> 检索结果
342. Reduced risk of pancreatic cancer associated with asthma and nasal allergies.
作者: Paulina Gomez-Rubio.;Jan-Paul Zock.;Marta Rava.;Mirari Marquez.;Linda Sharp.;Manuel Hidalgo.;Alfredo Carrato.;Lucas Ilzarbe.;Christoph Michalski.;Xavier Molero.;Antoni Farré.;José Perea.;William Greenhalf.;Michael O'Rorke.;Adonina Tardón.;Thomas Gress.;Victor Barberà.;Tatjana Crnogorac-Jurcevic.;Enrique Domínguez-Muñoz.;Luís Muñoz-Bellvís.;Cristina Alvarez-Urturi.;Joaquim Balcells.;Luis Barneo.;Eithne Costello.;Carmen Guillén-Ponce.;Jörg Kleeff.;Bo Kong.;Rita Lawlor.;Matthias Löhr.;Josefina Mora.;Lim Murray.;Damian O'Driscoll.;Pablo Peláez.;Ignasi Poves.;Aldo Scarpa.;Francisco X Real.;Núria Malats.; .
来源: Gut. 2017年66卷2期314-322页
Studies indicate an inverse association between ductal adenocarcinoma of the pancreas (PDAC) and nasal allergies. However, controversial findings are reported for the association with asthma. Understanding PDAC risk factors will help us to implement appropriate strategies to prevent, treat and diagnose this cancer. This study assessed and characterised the association between PDAC and asthma and corroborated existing reports regarding the association between allergies and PDAC risk.
343. Structural robustness of the gut mucosal microbiota is associated with Crohn's disease remission after surgery.
作者: S Mondot.;P Lepage.;P Seksik.;M Allez.;X Tréton.;Y Bouhnik.;J F Colombel.;M Leclerc.;P Pochart.;J Doré.;P Marteau.; .
来源: Gut. 2016年65卷6期954-62页
Preventing postoperative recurrence after ileocolonic resection (ICR) for Crohn's disease (CD) is challenging. Defining the disturbances of the microbial composition and community structure after ICR and their link with early disease recurrence is crucial.
344. Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy.
作者: An Moonen.;Vito Annese.;Ann Belmans.;Albert J Bredenoord.;Stanislas Bruley des Varannes.;Mario Costantini.;Bertrand Dousset.;J I Elizalde.;Uberto Fumagalli.;Marianne Gaudric.;Antonio Merla.;Andre J Smout.;Jan Tack.;Giovanni Zaninotto.;Olivier R Busch.;Guy E Boeckxstaens.
来源: Gut. 2016年65卷5期732-9页
Achalasia is a chronic motility disorder of the oesophagus for which laparoscopic Heller myotomy (LHM) and endoscopic pneumodilation (PD) are the most commonly used treatments. However, prospective data comparing their long-term efficacy is lacking.
347. Detection of gluten immunogenic peptides in the urine of patients with coeliac disease reveals transgressions in the gluten-free diet and incomplete mucosal healing.
作者: María de Lourdes Moreno.;Ángel Cebolla.;Alba Muñoz-Suano.;Carolina Carrillo-Carrion.;Isabel Comino.;Ángeles Pizarro.;Francisco León.;Alfonso Rodríguez-Herrera.;Carolina Sousa.
来源: Gut. 2017年66卷2期250-257页
Gluten-free diet (GFD) is the only management for coeliac disease (CD). Available methods to assess GFD compliance are insufficiently sensitive to detect occasional dietary transgressions that may cause gut mucosal damage. We aimed to develop a method to determine gluten intake and monitor GFD compliance in patients with CD and to evaluate its correlation with mucosal damage.
349. Clinical risk factors of colorectal cancer in patients with serrated polyposis syndrome: a multicentre cohort analysis.
作者: J E G IJspeert.;S A Q Rana.;N S S Atkinson.;Y J van Herwaarden.;B A J Bastiaansen.;M E van Leerdam.;S Sanduleanu.;T M Bisseling.;M C W Spaander.;S K Clark.;G A Meijer.;N van Lelyveld.;J J Koornstra.;I D Nagtegaal.;J E East.;A Latchford.;E Dekker.; .
来源: Gut. 2017年66卷2期278-284页
Serrated polyposis syndrome (SPS) is accompanied by an increased risk of colorectal cancer (CRC). Patients fulfilling the clinical criteria, as defined by the WHO, have a wide variation in CRC risk. We aimed to assess risk factors for CRC in a large cohort of patients with SPS and to evaluate the risk of CRC during surveillance.
350. HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice.
作者: Jannick Prentoe.;Lieven Verhoye.;Rodrigo Velázquez Moctezuma.;Caroline Buysschaert.;Ali Farhoudi.;Richard Wang.;Harvey Alter.;Philip Meuleman.;Jens Bukh.
来源: Gut. 2016年65卷12期1988-1997页
HCV is a major cause of chronic liver disease worldwide, but the role of neutralising antibodies (nAbs) in its natural history remains poorly defined. We analysed the in vivo role of hypervariable region 1 (HVR1) for HCV virion properties, including nAb susceptibility.
351. Improving safety of autologous haematopoietic stem cell transplantation in patients with Crohn's disease.
作者: Aranzazu Jauregui-Amezaga.;Montserrat Rovira.;Pedro Marín.;Azucena Salas.;Susana Pinó-Donnay.;Faust Feu.;J Ignasi Elizalde.;Francesc Fernández-Avilés.;Carmen Martínez.;Gonzalo Gutiérrez.;Laura Rosiñol.;Enric Carreras.;Alvaro Urbano.;Miguel Lozano.;Joan Cid.;María Suárez-Lledó.;Josep Mensa.;Jordi Rimola.;Sonia Rodríguez.;Mari Carme Masamunt.;Dolors Comas.;Irene Ruíz.;Anna Ramírez-Morros.;Marta Gallego.;Ingrid Ordás.;Julian Panés.;Elena Ricart.
来源: Gut. 2016年65卷9期1456-62页
To evaluate the feasibility and toxicity of autologous haematopoietic stem cell transplantation (HSCT) for the treatment of refractory Crohn's disease (CD).
352. Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis.
作者: Alexander C Ford.;Pavit Luthra.;Jan Tack.;Guy E Boeckxstaens.;Paul Moayyedi.;Nicholas J Talley.
来源: Gut. 2017年66卷3期411-420页
Functional dyspepsia (FD) is a chronic gastroduodenal disorder. Individuals with FD demonstrate visceral hypersensitivity, abnormal central pain processing, and low mood, but it is unclear whether psychotropic drugs are an effective treatment for the condition. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs).
353. Apelin targets gut contraction to control glucose metabolism via the brain.
作者: Audren Fournel.;Anne Drougard.;Thibaut Duparc.;Alysson Marlin.;Stuart M Brierley.;Joel Castro.;Sophie Le-Gonidec.;Bernard Masri.;André Colom.;Alexandre Lucas.;Perrine Rousset.;Nicolas Cenac.;Nathalie Vergnolle.;Philippe Valet.;Patrice D Cani.;Claude Knauf.
来源: Gut. 2017年66卷2期258-269页
The gut-brain axis is considered as a major regulatory checkpoint in the control of glucose homeostasis. The detection of nutrients and/or hormones in the duodenum informs the hypothalamus of the host's nutritional state. This process may occur via hypothalamic neurons modulating central release of nitric oxide (NO), which in turn controls glucose entry into tissues. The enteric nervous system (ENS) modulates intestinal contractions in response to various stimuli, but the importance of this interaction in the control of glucose homeostasis via the brain is unknown. We studied whether apelin, a bioactive peptide present in the gut, regulates ENS-evoked contractions, thereby identifying a new physiological partner in the control of glucose utilisation via the hypothalamus.
358. Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis.
作者: Helga Westerlind.;Marie-Rose Mellander.;Francesca Bresso.;Andreas Munch.;Ferdinando Bonfiglio.;Ghazaleh Assadi.;Joseph Rafter.;Matthias Hübenthal.;Wolfgang Lieb.;Henrik Källberg.;Boel Brynedal.;Leonid Padyukov.;Jonas Halfvarson.;Leif Törkvist.;Jan Bjork.;Anna Andreasson.;Lars Agreus.;Sven Almer.;Stephan Miehlke.;Ahmed Madisch.;Bodil Ohlsson.;Robert Löfberg.;Rolf Hultcrantz.;Andre Franke.;Mauro D'Amato.
来源: Gut. 2017年66卷3期421-428页
Collagenous colitis (CC) is a major cause of chronic non-bloody diarrhoea, particularly in the elderly female population. The aetiology of CC is unknown, and still poor is the understanding of its pathogenesis. This possibly involves dysregulated inflammation and immune-mediated reactions in genetically predisposed individuals, but the contribution of genetic factors to CC is underinvestigated. We systematically tested immune-related genes known to impact the risk of several autoimmune diseases for their potential CC-predisposing role.
359. Faecal haemoglobin concentration influences risk prediction of interval cancers resulting from inadequate colonoscopy quality: analysis of the Taiwanese Nationwide Colorectal Cancer Screening Program.
作者: Sherry Yueh-Hsia Chiu.;Shu-Ling Chuang.;Sam Li-Sheng Chen.;Amy Ming-Fang Yen.;Jean Ching-Yuan Fann.;Dun-Cheng Chang.;Yi-Chia Lee.;Ming-Shiang Wu.;Chu-Kuang Chou.;Wen-Feng Hsu.;Shu-Ti Chiou.;Han-Mo Chiu.
来源: Gut. 2017年66卷2期293-300页
Interval colorectal cancer (CRC) after colonoscopy may affect effectiveness and cost-effectiveness of screening programmes. We aimed to investigate whether and how faecal haemoglobin concentration (FHbC) of faecal immunochemical testing (FIT) affected the risk prediction of interval cancer (IC) caused by inadequate colonoscopy quality in a FIT-based population screening programme.
|