261. Live birth and adverse birth outcomes in women with ulcerative colitis and Crohn's disease receiving assisted reproduction: a 20-year nationwide cohort study.
作者: B M Nørgård.;P V Larsen.;J Fedder.;P S de Silva.;M D Larsen.;S Friedman.
来源: Gut. 2016年65卷5期767-76页
To examine the chance of live births and adverse birth outcomes in women with ulcerative colitis (UC) and Crohn's disease (CD) compared with women without inflammatory bowel disease (IBD) who have undergone assisted reproductive technology (ART) treatments.
263. Spleen size for the prediction of clinical outcome in patients with primary sclerosing cholangitis.
作者: Hanno Ehlken.;Raluca Wroblewski.;Christophe Corpechot.;Lionel Arrivé.;Susanne Lezius.;Johannes Hartl.;Ulrike W Denzer.;Ansgar W Lohse.;Olivier Chazouilleres.;Christoph Schramm.
来源: Gut. 2016年65卷7期1230-2页 264. Functional annotation of colorectal cancer susceptibility loci identifies MLH1 rs1800734 associated with MSI patients.
作者: Gaoxiang Ma.;Yuqiu Ge.;Dongying Gu.;Mulong Du.;Haiyan Chu.;Jinfei Chen.;Zhengdong Zhang.;Meilin Wang.
来源: Gut. 2016年65卷7期1227-8页 265. Detection rate of serrated polyps and serrated polyposis syndrome in colorectal cancer screening cohorts: a European overview.
作者: J E G IJspeert.;R Bevan.;C Senore.;M F Kaminski.;E J Kuipers.;A Mroz.;X Bessa.;P Cassoni.;C Hassan.;A Repici.;F Balaguer.;C J Rees.;E Dekker.
来源: Gut. 2017年66卷7期1225-1232页
The role of serrated polyps (SPs) as colorectal cancer precursor is increasingly recognised. However, the true prevalence SPs is largely unknown. We aimed to evaluate the detection rate of SPs subtypes as well as serrated polyposis syndrome (SPS) among European screening cohorts.
268. Detection rate and predictive factors of sessile serrated polyps in an organised colorectal cancer screening programme with immunochemical faecal occult blood test: the EQuIPE study (Evaluating Quality Indicators of the Performance of Endoscopy).
作者: Manuel Zorzi.;Carlo Senore.;Filippo Da Re.;Alessandra Barca.;Luigina Ada Bonelli.;Renato Cannizzaro.;Giovanni de Pretis.;Lucia Di Furia.;Emilio Di Giulio.;Paola Mantellini.;Carlo Naldoni.;Romano Sassatelli.;Douglas K Rex.;Marco Zappa.;Cesare Hassan.; .
来源: Gut. 2017年66卷7期1233-1240页
To assess detection rate and predictive factors of sessile serrated polyps (SSPs) in organised colorectal cancer (CRC) screening programmes based on the faecal immunochemical test (FIT).
269. Algorithm to rule out clinically significant portal hypertension combining Shear-wave elastography of liver and spleen: a prospective multicentre study.
作者: Christian Jansen.;Christopher Bogs.;Wim Verlinden.;Maja Thiele.;Philipp Möller.;Jan Görtzen.;Jennifer Lehmann.;Michael Praktiknjo.;Johannes Chang.;Aleksander Krag.;Christian P Strassburg.;Sven Francque.;Jonel Trebicka.
来源: Gut. 2016年65卷6期1057-8页 272. The safety of vedolizumab for ulcerative colitis and Crohn's disease.
作者: Jean-Frédéric Colombel.;Bruce E Sands.;Paul Rutgeerts.;William Sandborn.;Silvio Danese.;Geert D'Haens.;Remo Panaccione.;Edward V Loftus.;Serap Sankoh.;Irving Fox.;Asit Parikh.;Catherine Milch.;Brihad Abhyankar.;Brian G Feagan.
来源: Gut. 2017年66卷5期839-851页
Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the safety of vedolizumab.
273. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.
作者: Joel Castro.;Andrea M Harrington.;Sonia Garcia-Caraballo.;Jessica Maddern.;Luke Grundy.;Jingming Zhang.;Guy Page.;Paul E Miller.;David J Craik.;David J Adams.;Stuart M Brierley.
来源: Gut. 2017年66卷6期1083-1094页
α-Conotoxin Vc1.1 is a small disulfide-bonded peptide from the venom of the marine cone snail Conus victoriae. Vc1.1 has antinociceptive actions in animal models of neuropathic pain, but its applicability to inhibiting human dorsal root ganglion (DRG) neuroexcitability and reducing chronic visceral pain (CVP) is unknown.
274. Solving a disaster following coronary bypass operation.
作者: Philipp-Alexander Neumann.;Mike Laukoetter.;Rudolph Mennigen.;Linus Kebschull.;Dominik Bettenworth.;Frank Lenze.;Hansjoerg Ullerich.;Norbert Senninger.;Thorsten Vowinkel.
来源: Gut. 2016年65卷10期1601页 275. The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls.
作者: Martin Kummen.;Kristian Holm.;Jarl Andreas Anmarkrud.;Ståle Nygård.;Mette Vesterhus.;Marte L Høivik.;Marius Trøseid.;Hanns-Ulrich Marschall.;Erik Schrumpf.;Bjørn Moum.;Helge Røsjø.;Pål Aukrust.;Tom H Karlsen.;Johannes R Hov.
来源: Gut. 2017年66卷4期611-619页
Gut microbiota could influence gut, as well as hepatic and biliary immune responses. We therefore thoroughly characterised the gut microbiota in primary sclerosing cholangitis (PSC) compared with healthy controls (HC) and patients with ulcerative colitis without liver disease.
276. STAT4-associated natural killer cell tolerance following liver transplantation.
作者: K M Jamil.;T J Hydes.;K S Cheent.;S A Cassidy.;J A Traherne.;J Jayaraman.;J Trowsdale.;G J Alexander.;A-M Little.;H McFarlane.;M A Heneghan.;M A Purbhoo.;S I Khakoo.
来源: Gut. 2017年66卷2期352-361页
Natural killer (NK) cells are important mediators of liver inflammation in chronic liver disease. The aim of this study was to investigate why liver transplants (LTs) are not rejected by NK cells in the absence of human leukocyte antigen (HLA) matching, and to identify a tolerogenic NK cell phenotype.
277. Quantitative evaluation of human bone mesenchymal stem cells rescuing fulminant hepatic failure in pigs.
作者: Dongyan Shi.;Jianing Zhang.;Qian Zhou.;Jiaojiao Xin.;Jing Jiang.;Longyan Jiang.;Tianzhou Wu.;Jiang Li.;Wenchao Ding.;Jun Li.;Suwan Sun.;Jianzhou Li.;Ning Zhou.;Liyuan Zhang.;Linfeng Jin.;Shaorui Hao.;Pengcheng Chen.;Hongcui Cao.;Mingding Li.;Lanjuan Li.;Xin Chen.;Jun Li.
来源: Gut. 2017年66卷5期955-964页
Stem cell transplantation provides a promising alternative for the treatment of fulminant hepatic failure (FHF). However, it lacks fundamental understanding of stem cells' activities. Our objective was to clarify stem cell-recipient interactions for overcoming barriers to clinical application.
278. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis.
作者: Kelly A Whelan.;Jamie F Merves.;Veronique Giroux.;Koji Tanaka.;Andy Guo.;Prasanna M Chandramouleeswaran.;Alain J Benitez.;Kara Dods.;Jianwen Que.;Joanne C Masterson.;Shahan D Fernando.;Bridget C Godwin.;Andres J Klein-Szanto.;Kudakwashe Chikwava.;Eduardo D Ruchelli.;Kathryn E Hamilton.;Amanda B Muir.;Mei-Lun Wang.;Glenn T Furuta.;Gary W Falk.;Jonathan M Spergel.;Hiroshi Nakagawa.
来源: Gut. 2017年66卷7期1197-1207页
The influence of eosinophilic oesophagitis (EoE)-associated inflammation upon oesophageal epithelial biology remains poorly understood. We investigated the functional role of autophagy in oesophageal epithelial cells (keratinocytes) exposed to the inflammatory EoE milieu.
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