2700. Feasibility and effectiveness of oral cholera vaccine in an urban endemic setting in Bangladesh: a cluster randomised open-label trial.
作者: Firdausi Qadri.;Mohammad Ali.;Fahima Chowdhury.;Ashraful Islam Khan.;Amit Saha.;Iqbal Ansary Khan.;Yasmin A Begum.;Taufiqur R Bhuiyan.;Mohiul Islam Chowdhury.;Md Jasim Uddin.;Jahangir A M Khan.;Atique Iqbal Chowdhury.;Anisur Rahman.;Shah Alam Siddique.;Muhammad Asaduzzaman.;Afroza Akter.;Arifuzzaman Khan.;Young Ae You.;Ashraf Uddin Siddik.;Nirod Chandra Saha.;Alamgir Kabir.;Baizid Khoorshid Riaz.;Shwapon Kumar Biswas.;Farzana Begum.;Leanne Unicomb.;Stephen P Luby.;Alejandro Cravioto.;John D Clemens.
来源: Lancet. 2015年386卷10001期1362-1371页
Cholera is endemic in Bangladesh with epidemics occurring each year. The decision to use a cheap oral killed whole-cell cholera vaccine to control the disease depends on the feasibility and effectiveness of vaccination when delivered in a public health setting. We therefore assessed the feasibility and protective effect of delivering such a vaccine through routine government services in urban Bangladesh and evaluated the benefit of adding behavioural interventions to encourage safe drinking water and hand washing to vaccination in this setting.
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