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235. Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals.
作者: Li Liu.;Shefali Oza.;Dan Hogan.;Yue Chu.;Jamie Perin.;Jun Zhu.;Joy E Lawn.;Simon Cousens.;Colin Mathers.;Robert E Black.
来源: Lancet. 2016年388卷10063期3027-3035页
Despite remarkable progress in the improvement of child survival between 1990 and 2015, the Millennium Development Goal (MDG) 4 target of a two-thirds reduction of under-5 mortality rate (U5MR) was not achieved globally. In this paper, we updated our annual estimates of child mortality by cause to 2000-15 to reflect on progress toward the MDG 4 and consider implications for the Sustainable Development Goals (SDG) target for child survival.
236. Fractional dosing of yellow fever vaccine to extend supply: a modelling study.
作者: Joseph T Wu.;Corey M Peak.;Gabriel M Leung.;Marc Lipsitch.
来源: Lancet. 2016年388卷10062期2904-2911页
The ongoing yellow fever epidemic in Angola strains the global vaccine supply, prompting WHO to adopt dose sparing for its vaccination campaign in Kinshasa, Democratic Republic of the Congo, in July-August, 2016. Although a 5-fold fractional-dose vaccine is similar to standard-dose vaccine in safety and immunogenicity, efficacy is untested. There is an urgent need to ensure the robustness of fractional-dose vaccination by elucidation of the conditions under which dose fractionation would reduce transmission.
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