222. Prevalence and predictors of patient no-shows to outpatient endoscopic procedures scheduled with anesthesia.
Demand for endoscopic procedures scheduled with anesthesia is increasing and no-show to appointments carries significant patient health and financial impact, yet little is known about predictors of no-show.
223. Endoscopic ultrasound-guided sampling of solid pancreatic masses: 22-gauge aspiration versus 25-gauge biopsy needles.
作者: Min Jae Yang.;Hyunee Yim.;Jae Chul Hwang.;Dakeun Lee.;Young Bae Kim.;Sun Gyo Lim.;Soon Sun Kim.;Joon Koo Kang.;Byung Moo Yoo.;Jin Hong Kim.
来源: BMC Gastroenterol. 2015年15卷122页
Biopsy needles have recently been developed to obtain both cytological and histological specimens during endoscopic ultrasound (EUS). We conducted this study to compare 22-gauge (G) fine needle aspiration (FNA) needles, which have been the most frequently used, and new 25G fine needle biopsy (FNB) needles for EUS-guided sampling of solid pancreatic masses.
228. Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.
作者: Yuchen Xia.;Daniela Stadler.;Julie Lucifora.;Florian Reisinger.;Dennis Webb.;Marianna Hösel.;Thomas Michler.;Karin Wisskirchen.;Xiaoming Cheng.;Ke Zhang.;Wen-Min Chou.;Jochen M Wettengel.;Antje Malo.;Felix Bohne.;Dieter Hoffmann.;Florian Eyer.;Robert Thimme.;Christine S Falk.;Wolfgang E Thasler.;Mathias Heikenwalder.;Ulrike Protzer.
来源: Gastroenterology. 2016年150卷1期194-205页
Viral clearance involves immune cell cytolysis of infected cells. However, studies of hepatitis B virus (HBV) infection in chimpanzees have indicated that cytokines released by T cells also can promote viral clearance via noncytolytic processes. We investigated the noncytolytic mechanisms by which T cells eliminate HBV from infected hepatocytes.
237. Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin.
作者: Viet Loan Dao Thi.;Yannick Debing.;Xianfang Wu.;Charles M Rice.;Johan Neyts.;Darius Moradpour.;Jérôme Gouttenoire.
来源: Gastroenterology. 2016年150卷1期82-85.e4页
Infection with hepatitis E virus genotype 3 may result in chronic hepatitis in immunocompromised patients. Reduction of immunosuppression or treatment with ribavirin or pegylated interferon-α can result in viral clearance. However, safer and more effective treatment options are needed. Here, we show that sofosbuvir inhibits the replication of hepatitis E virus genotype 3 both in subgenomic replicon systems as well as a full-length infectious clone. Moreover, the combination of sofosbuvir and ribavirin results in an additive antiviral effect. Sofosbuvir may be considered as an add-on therapy to ribavirin for the treatment of chronic hepatitis E in immunocompromised patients.
238. Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
作者: Wanglong Qiu.;Sophia M Tang.;Sohyae Lee.;Andrew T Turk.;Anthony N Sireci.;Anne Qiu.;Christian Rose.;Chuangao Xie.;Jan Kitajewski.;Hui-Ju Wen.;Howard C Crawford.;Peter A Sims.;Ralph H Hruban.;Helen E Remotti.;Gloria H Su.
来源: Gastroenterology. 2016年150卷1期218-228.e12页
Activin, a member of the transforming growth factor-β (TGFB) family, might be involved in pancreatic tumorigenesis, similar to other members of the TGFB family. Human pancreatic ductal adenocarcinomas contain somatic mutations in the activin A receptor type IB (ACVR1B) gene, indicating that ACVR1B could be a suppressor of pancreatic tumorigenesis.
239. Esophagogastroduodenal pneumatosis with subsequent pneumoporta and intramural duodenal hematoma after endoscopic hemostasis: a case report.
Esophagogastroduodenal pneumatosis is the presence of air in esophagus, stomach, and duodenum simultaneously, which have never been described in the literature. Intramural duodenal hematoma (IDH) rarely occurs after endoscopic intervention. The diagnosis and treatment in both conditions are great challenge in daily practice.
240. Case report of gastric outlet obstruction from metastatic lobular breast carcinoma.
作者: Alexander H Kim.;M Joshua Shellenberger.;Zong Ming Chen.;Jinhong Li.
来源: BMC Gastroenterol. 2015年15卷120页
The most common malignancy to cause gastric outlet obstruction is primary gastric adenocarcinoma and it is followed by carcinoma of the pancreas and gallbladder. Herein, we report a case of gastric outlet obstruction secondary to metastatic lobular breast carcinoma.
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