当前位置: 首页 >> 检索结果
1841. Alterations of the bile microbiome in primary sclerosing cholangitis.
作者: Timur Liwinski.;Roman Zenouzi.;Clara John.;Hanno Ehlken.;Malte C Rühlemann.;Corinna Bang.;Stefan Groth.;Wolfgang Lieb.;Marcus Kantowski.;Nils Andersen.;Guido Schachschal.;Tom H Karlsen.;Johannes R Hov.;Thomas Rösch.;Ansgar W Lohse.;Joerg Heeren.;Andre Franke.;Christoph Schramm.
来源: Gut. 2020年69卷4期665-672页
Patients with primary sclerosing cholangitis (PSC) display an altered colonic microbiome compared with healthy controls. However, little is known on the bile duct microbiome and its interplay with bile acid metabolism in PSC.
1842. Duration of organ failure impacts mortality in acute pancreatitis.
作者: Na Shi.;Tingting Liu.;Daniel de la Iglesia-Garcia.;Lihui Deng.;Tao Jin.;Lan Lan.;Ping Zhu.;Weiming Hu.;Zongguang Zhou.;Vikesh Singh.;J Enrique Dominguez-Munoz.;John Windsor.;Wei Huang.;Qing Xia.;Robert Sutton.
来源: Gut. 2020年69卷3期604-605页 1843. Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial.
作者: Grace L H Wong.;Louis H S Lau.;Jessica Y L Ching.;Yee-Kit Tse.;Rachel H Y Ling.;Vincent W S Wong.;Philip W Y Chiu.;James Y W Lau.;Francis K L Chan.
来源: Gut. 2020年69卷4期652-657页
Patients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have a considerable risk of recurrent ulcer complications. We hypothesised that a proton pump inhibitor (lansoprazole) is superior to a histamine 2 receptor antagonist (famotidine) for the prevention of recurrent ulcer bleeding in such patients.
1844. First known case of paediatric inflammatory bowel disease in a western lowland gorilla may be linked to a familial mutation in the MEFV gene.
作者: Britt-Sabina Petersen.;Bernd Bokemeyer.;Christian Wenker.;Stefan Hoby.;Katrin Baumgartner.;Hermann Will.;Marc P Hoeppner.;Stefan Schreiber.;Ingo Mecklenburg.;Andre Franke.
来源: Gut. 2020年69卷6期1153-1154页 1846. Absence of hepatitis E virus RNA in semen samples of infertile male in China.
作者: Lin Wang.;Zhe Zhang.;Jingyi Shu.;Haitao Zhang.;Yuzhuo Yang.;Zhaochao Liang.;Qiyu He.;Weijin Huang.;Youchun Wang.;Hui Zhuang.;Hui Jiang.;Ling Wang.
来源: Gut. 2020年69卷7期1363-1364页 1847. Yogurt consumption and risk of conventional and serrated precursors of colorectal cancer.
作者: Xiaobin Zheng.;Kana Wu.;Mingyang Song.;Shuji Ogino.;Charles S Fuchs.;Andrew T Chan.;Edward L Giovannucci.;Yin Cao.;Xuehong Zhang.
来源: Gut. 2020年69卷5期970-972页 1851. β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor.
作者: Patrick Weil.;Rhea van den Bruck.;Thomas Ziegenhals.;Stefan Juranek.;Daniel Goedde.;Valerie Orth.;Stefan Wirth.;Andreas C Jenke.;Jan Postberg.
来源: Gut. 2020年69卷7期1359-1361页 1852. Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome.
作者: Sangeetha N Kalimuthu.;Gavin W Wilson.;Robert C Grant.;Matthew Seto.;Grainne O'Kane.;Rajkumar Vajpeyi.;Faiyaz Notta.;Steven Gallinger.;Runjan Chetty.
来源: Gut. 2020年69卷2期317-328页
Transcriptional analyses have identified several distinct molecular subtypes in pancreatic ductal adenocarcinoma (PDAC) that have prognostic and potential therapeutic significance. However, to date, an indepth, clinicomorphological correlation of these molecular subtypes has not been performed. We sought to identify specific morphological patterns to compare with known molecular subtypes, interrogate their biological significance, and furthermore reappraise the current grading system in PDAC.
1853. Alterations of gut microbiome in autoimmune hepatitis.
作者: Yiran Wei.;Yanmei Li.;Li Yan.;Chunyan Sun.;Qi Miao.;Qixia Wang.;Xiao Xiao.;Min Lian.;Bo Li.;Yong Chen.;Jun Zhang.;You Li.;Bingyuan Huang.;Yikang Li.;Qin Cao.;Zhuping Fan.;Xiaoyu Chen.;Jing-Yuan Fang.;Merrill Eric Gershwin.;Ruqi Tang.;Xiong Ma.
来源: Gut. 2020年69卷3期569-577页
The significance of the liver-microbiome axis has been increasingly recognised as a major modulator of autoimmunity. The aim of this study was to take advantage of a large well-defined corticosteroids treatment-naïve group of patients with autoimmune hepatitis (AIH) to rigorously characterise gut dysbiosis compared with healthy controls.
1854. Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study.
作者: Sanjay K Murthy.;Jahanara Begum.;Eric I Benchimol.;Charles N Bernstein.;Gilaad G Kaplan.;Jeffrey D McCurdy.;Harminder Singh.;Laura Targownik.;Monica Taljaard.
来源: Gut. 2020年69卷2期274-282页
To better understand the real-world impact of biologic therapy in persons with Crohn's disease (CD) and ulcerative colitis (UC), we evaluated the effect of marketplace introduction of infliximab on the population rates of hospitalisations and surgeries and public payer drug costs.
1855. Milk polar lipids reduce lipid cardiovascular risk factors in overweight postmenopausal women: towards a gut sphingomyelin-cholesterol interplay.
作者: Cécile Vors.;Laurie Joumard-Cubizolles.;Manon Lecomte.;Emmanuel Combe.;Lemlih Ouchchane.;Jocelyne Drai.;Ketsia Raynal.;Florent Joffre.;Laure Meiller.;Mélanie Le Barz.;Patrice Gaborit.;Aurélie Caille.;Monique Sothier.;Carla Domingues-Faria.;Adeline Blot.;Aurélie Wauquier.;Emilie Blond.;Valérie Sauvinet.;Geneviève Gésan-Guiziou.;Jean-Pierre Bodin.;Philippe Moulin.;David Cheillan.;Hubert Vidal.;Béatrice Morio.;Eddy Cotte.;Françoise Morel-Laporte.;Martine Laville.;Annick Bernalier-Donadille.;Stéphanie Lambert-Porcheron.;Corinne Malpuech-Brugère.;Marie-Caroline Michalski.
来源: Gut. 2020年69卷3期487-501页
To investigate whether milk polar lipids (PL) impact human intestinal lipid absorption, metabolism, microbiota and associated markers of cardiometabolic health.
1858. Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
作者: Ruiping Wang.;Shumei Song.;Kazuto Harada.;Fatemeh Ghazanfari Amlashi.;Brian Badgwell.;Melissa Pool Pizzi.;Yan Xu.;Wei Zhao.;Xiaochuan Dong.;Jiangkang Jin.;Ying Wang.;Ailing Scott.;Lang Ma.;Longfei Huo.;Diego Vicente.;Mariela Blum Murphy.;Namita Shanbhag.;Ghia Tatlonghari.;Irene Thomas.;Jane Rogers.;Makoto Kobayashi.;Jody Vykoukal.;Jeannelyn Santiano Estrella.;Sinchita Roy-Chowdhuri.;Guangchun Han.;Shaojun Zhang.;Xizeng Mao.;Xingzhi Song.;Jianhua Zhang.;Jian Gu.;Randy L Johnson.;George Adrian Calin.;Guang Peng.;Ju-Seog Lee.;Samir M Hanash.;Andrew Futreal.;Zhenning Wang.;Linghua Wang.;Jaffer A Ajani.
来源: Gut. 2020年69卷1期18-31页
Peritoneal carcinomatosis (PC) occurs frequently in patients with gastric adenocarcinoma (GAC) and confers a poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC's development/progression remain largely unknown. We characterised exome/transcriptome/immune landscapes of PC cells from patients with GAC aiming to identify novel therapeutic targets.
1859. Modulation of cytokine patterns and microbiome during pregnancy in IBD.
作者: Janine van der Giessen.;Dana Binyamin.;Anna Belogolovski.;Sigal Frishman.;Kinneret Tenenbaum-Gavish.;Eran Hadar.;Yoram Louzoun.;Maikel Petrus Peppelenbosch.;Christien Janneke van der Woude.;Omry Koren.;Gwenny Manel Fuhler.
来源: Gut. 2020年69卷3期473-486页
Pregnancy may affect the disease course of IBD. Both pregnancy and IBD are associated with altered immunology and intestinal microbiology. However, to what extent immunological and microbial profiles are affected by pregnancy in patients with IBD remains unclear.
|