"N Engl J Med"[journal] 检索结果

981. Pulsed Field or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation.

作者: Paschalis Karakasis.;Nikolaos Fragakis.
来源: N Engl J Med. 2025年393卷5期518-519页

982. Pulsed Field or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation.

作者: Jacob N Blackwell.;Norman C Wang.;Aditya Bhonsale.
来源: N Engl J Med. 2025年393卷5期518页

983. Reform and Remedy for Imprecision and Inequity - Ending the Race-Based Evaluation of Occupational Pulmonary Impairment.

作者: Rohan Khazanchi.;Sanja Stanojevic.;Stella E Hines.;Nirav R Bhakta.
来源: N Engl J Med. 2025年393卷5期508-514页

984. Opening the Door to Tailored Treatment in Newly Diagnosed Multiple Myeloma.

作者: Paul G Richardson.;Nikhil C Munshi.;Dan L Longo.
来源: N Engl J Med. 2025年393卷5期498-500页

985. Case 22-2025: A 19-Year-Old Woman with Seizurelike Activity and Odd Behaviors.

作者: Judith A Restrepo.;Amirkasra Mojtahed.;Leah W Morelli.;Nagagopal Venna.;Gulisa Turashvili.
来源: N Engl J Med. 2025年393卷5期488-496页

986. Spontaneous Intracranial Hypotension.

作者: Syeda Busmah Owais.;Yasaman Kianirad.
来源: N Engl J Med. 2025年393卷5期487页

987. Motor Vehicle Crash Prevention.

作者: Sheila G Klauer.;Zachary R Doerzaph.
来源: N Engl J Med. 2025年393卷5期479-486页

988. Resolution of Squamous-Cell Carcinoma by Restoring T-Cell Receptor Signaling.

作者: Peiying Ye.;Jenna R E Bergerson.;Isaac Brownell.;Gabriel J Starrett.;Roshini S Abraham.;Megan V Anderson.;Triscia Martin.;Derek MacMath.;Hye Sun Kuehn.;Jyothi Padiadpu.;Siqi Zhao.;Sergio D Rosenzweig.;Roxane Tussiwand.;Warren J Leonard.;Stefania Pittaluga.;Mark Raffeld.;Danielle E Arnold.;Andrea Lisco.
来源: N Engl J Med. 2025年393卷5期469-478页

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is dispensable for the maintenance of cutaneous SCC. Here, we describe a woman with benign and malignant HPV-related diseases that include a recurrent, unresectable, invasive cutaneous SCC with β-HPV19 genomic integration in the context of germline pathogenic mutations in ZAP70, an adapter required for T-cell receptor (TCR) signal transduction. Restoration of the integrity of TCR signaling by allogeneic hematopoietic-cell transplantation led to the resolution of all HPV-related diseases, thereby revealing a direct role of β-HPV in skin carcinogenesis in hosts with defective adaptive T-cell responses. (Funded by the National Institutes of Health.).

989. Human Papillomavirus and Cancer.

作者: Julie R Barzilay.;Sarah Feldman.;Alison E Burke.;Emily Ling.;Scott Williams.;Caren G Solomon.
来源: N Engl J Med. 2025年393卷5期e6页

990. The Path Forward for Vaccine Policy in the United States.

作者: Helen Y Chu.;Noel T Brewer.;Edwin J Asturias.;Oliver Brooks.;Sybil Cineas.;Denise J Jamieson.;Mini Kamboj.;George A Kuchel.;Jamie Loehr.;Karyn Lyons.;Yvonne A Maldonado.;Charlotte A Moser.;Robert Schechter.;Albert C Shaw.;H Keipp Talbot.;Jane R Zucker.;Lin H Chen.
来源: N Engl J Med. 2025年393卷8期817-822页

991. Dismantling Public Health Infrastructure, Endangering American Lives.

作者: Thomas R Frieden.
来源: N Engl J Med. 2025年393卷7期625-627页

992. Progress Lost - The Unraveling of Medicaid and the Affordable Care Act.

作者: Jonathan Oberlander.
来源: N Engl J Med. 2025年393卷7期628-629页

993. Public Policies, Social Narratives, and Population Health.

作者: Atheendar S Venkataramani.;Pritpal S Tamber.;Anthony Iton.
来源: N Engl J Med. 2025年393卷5期419-421页

994. Spiderweb-like Vessels in Retinopathy of Prematurity.

作者: Xinyu Zhao.;Guoming Zhang.
来源: N Engl J Med. 2025年393卷5期e7页

995. Into the Valley of the Sick.

作者: Sloane Wesloh.
来源: N Engl J Med. 2025年393卷5期421-423页

996. Preventive Care at the Supreme Court.

作者: Nicholas Bagley.
来源: N Engl J Med. 2025年393卷8期729-731页

997. Enteral Nutrition in Hospitalized Adults. Reply.

作者: Leah Gramlich.;Peggi Guenter.
来源: N Engl J Med. 2025年393卷4期416页

998. Enteral Nutrition in Hospitalized Adults.

作者: Daniel E Tripoloni.;Mercedes Canaro García.;Juana Gall.
来源: N Engl J Med. 2025年393卷4期415页

999. Enteral Nutrition in Hospitalized Adults.

作者: Thomas E Finucane.
来源: N Engl J Med. 2025年393卷4期415页

1000. Evolving Epidemiology of Mpox in Africa in 2024. Reply.

作者: Nicaise Ndembi.;Morenike O Folayan.;Salim S Abdool Karim.
来源: N Engl J Med. 2025年393卷4期414页

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