"N Engl J Med"[journal] 检索结果

781. Mimicking Complex Receptor Actions with Small(ish) Molecules.

作者: Derek B Lowe.
来源: N Engl J Med. 2025年393卷11期1133-1134页

782. An Aspirin a Day for Improved Colorectal Cancer Outcomes.

作者: Richard M Goldberg.;Jeffrey A Meyerhardt.
来源: N Engl J Med. 2025年393卷11期1131-1132页

783. Case 26-2025: An 11-Year-Old Girl with Chest Pain and Bone and Liver Lesions.

作者: Lindsay Pindyck Carter.;Sjirk J Westra.;Ann M Murray.;Sarah E Turbett.
来源: N Engl J Med. 2025年393卷11期1118-1127页

784. Primary Varicella Infection.

作者: Olivier van Not.;Daan Rauwerdink.
来源: N Engl J Med. 2025年393卷11期e18页

785. Tumor Lysis Syndrome.

作者: R Gregory Bociek.;Matthew Lunning.
来源: N Engl J Med. 2025年393卷11期1104-1116页

786. Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer.

作者: Anna Martling.;Ida Hed Myrberg.;Mef Nilbert.;Henrik Grönberg.;Fredrik Granath.;Martin Eklund.;Tom Öresland.;Lene H Iversen.;Carola Haapamäki.;Martin Janson.;Karin Westberg.;Josefin Segelman.;Urban Ersson.;Mattias Prytz.;Eva Angenete.;Rebecka Bergström.;Markus Mayrhofer.;Bengt Glimelius.;Johan Lindberg.; .
来源: N Engl J Med. 2025年393卷11期1051-1064页

Aspirin reduces the incidence of colorectal adenoma and colorectal cancer among high-risk persons. Observational studies suggest that aspirin may also improve disease-free survival after diagnosis, particularly among patients with tumors harboring somatic PIK3CA mutations. However, data from randomized trials are lacking.

787. Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease.

作者: Heather J Zar.;Louis J Bont.;Paolo Manzoni.;Flor M Muñoz.;Octavio Ramilo.;Po-Yen Chen.;José M Novoa.;Gustavo A Ordoñez.;Maria Tsolia.;Bruce Tapiéro.;Mirta I Acuña-Ávila.;Javier M Castellanos.;Michael Meyer.;Ichiro Morioka.;Ziqiang Chen.;Radha A Railkar.;Xiaowei Zang.;Brian M Maas.;Andrea Likos.;Andrew W Lee.;Luis A Castagnini.;Anushua Sinha.; .
来源: N Engl J Med. 2025年393卷13期1343-1345页

788. Studying Cancer Risks Associated with Diagnostic Procedures - Interpret Wisely.

作者: Lindsay M Morton.
来源: N Engl J Med. 2025年393卷13期1337-1339页

789. In Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus.

作者: Qian Wang.;Ze Xiu Xiao.;Xu Zheng.;Guihong Wang.;Linlin Yang.;Lina Shi.;Nan Xiang.;Xingbing Wang.;Gao-Feng Zha.;Georg Schett.;Zhu Chen.
来源: N Engl J Med. 2025年393卷15期1542-1544页

790. Small Steps, Big Ventricles: Idiopathic Normal-Pressure Hydrocephalus.

作者: Allan H Ropper.
来源: N Engl J Med. 2025年393卷22期2264-2266页

791. A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus.

作者: Mark G Luciano.;Michael A Williams.;Mark G Hamilton.;Heather L Katzen.;Nickolas A Dasher.;Abhay Moghekar.;Jun Hua.;Jan Malm.;Anders Eklund.;Naomi Alpert Abel.;Ahmed M Raslan.;Benjamin D Elder.;Jesse J Savage.;Daniel L Barrow.;Kiarash Shahlaie.;Hailey Jensen.;Thomas J Zwimpfer.;Jessica Wollett.;Daniel F Hanley.;Richard Holubkov.; .
来源: N Engl J Med. 2025年393卷22期2198-2209页

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, but the effectiveness of shunting is unclear.

792. Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment.

作者: Sean Wharton.;Louis J Aronne.;Adam Stefanski.;Nasreen F Alfaris.;Andreea Ciudin.;Koutaro Yokote.;Bruno Halpern.;Alpana P Shukla.;Chunmei Zhou.;Lisa Macpherson.;Sheryl E Allen.;Nadia N Ahmad.;Suzanne R Klise.; .
来源: N Engl J Med. 2025年393卷18期1796-1806页

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity.

793. Subcutaneous Panniculitis-like T-Cell Lymphoma.

作者: Shinri Okada.;Masashi Nishikubo.
来源: N Engl J Med. 2025年393卷11期1117页

794. Integrating Pharmacotherapy into Tobacco Control in Low- and Middle-Income Countries - A Critical Need.

作者: Nancy A Rigotti.;Natalie Walker.;Amer Siddiq Amer Nordin.
来源: N Engl J Med. 2025年393卷11期1041-1044页

795. Protecting Medicaid Enrollees with Chronic Conditions amid Work Requirements.

作者: John Z Ayanian.
来源: N Engl J Med. 2025年393卷11期1044-1046页

796. Reducing Tobacco Use Worldwide - A New Perspective Series.

作者: Nancy A Rigotti.;Kamran Siddiqi.;Debra Malina.;Genevra Pittman.;Darren B Taichman.;Kristine M Guinn.;Stephen Morrissey.
来源: N Engl J Med. 2025年393卷11期1129-1130页

797. Surprisingly Complex Assemblies from Low-Complexity Domains.

作者: Tanja Mittag.
来源: N Engl J Med. 2025年393卷12期1235-1238页

798. Transformative Research in Cystic Fibrosis.

作者: Eric J Sorscher.
来源: N Engl J Med. 2025年393卷12期1231-1234页

799. Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity.

作者: Sean Wharton.;Ildiko Lingvay.;Pawel Bogdanski.;Ruben Duque do Vale.;Stephan Jacob.;Tobias Karlsson.;Chaithra Shaji.;Domenica Rubino.;W Timothy Garvey.; .
来源: N Engl J Med. 2025年393卷11期1077-1087页

Oral semaglutide at a dose of 25 mg may provide an alternative treatment option to injectable semaglutide (2.4 mg) and higher-dose oral semaglutide (50 mg) for persons with overweight or obesity.

800. Once-Weekly Mazdutide in Obesity or Overweight. Reply.

作者: Linong Ji.;Lei Qian.
来源: N Engl J Med. 2025年393卷10期

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