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7745. Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers.
作者: Guillaume Mellon.;Sarah E Turbett.;Colin Worby.;Elizabeth Oliver.;A Taylor Walker.;Maroya Walters.;Paul Kelly.;Daniel T Leung.;Mark Knouse.;Stefan Hagmann.;Ashlee Earl.;Edward T Ryan.;Regina C LaRocque.
来源: N Engl J Med. 2020年382卷14期1372-1374页 7746. Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks.
作者: Natalie E Dean.;Pierre-Stéphane Gsell.;Ron Brookmeyer.;Forrest W Crawford.;Christl A Donnelly.;Susan S Ellenberg.;Thomas R Fleming.;M Elizabeth Halloran.;Peter Horby.;Thomas Jaki.;Philip R Krause.;Ira M Longini.;Sabue Mulangu.;Jean-Jacques Muyembe-Tamfum.;Martha C Nason.;Peter G Smith.;Rui Wang.;Ana M Henao-Restrepo.;Victor De Gruttola.
来源: N Engl J Med. 2020年382卷14期1366-1369页 7753. KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma.
作者: Michael Wang.;Javier Munoz.;Andre Goy.;Frederick L Locke.;Caron A Jacobson.;Brian T Hill.;John M Timmerman.;Houston Holmes.;Samantha Jaglowski.;Ian W Flinn.;Peter A McSweeney.;David B Miklos.;John M Pagel.;Marie-Jose Kersten.;Noel Milpied.;Henry Fung.;Max S Topp.;Roch Houot.;Amer Beitinjaneh.;Weimin Peng.;Lianqing Zheng.;John M Rossi.;Rajul K Jain.;Arati V Rao.;Patrick M Reagan.
来源: N Engl J Med. 2020年382卷14期1331-1342页
Patients with relapsed or refractory mantle-cell lymphoma who have disease progression during or after the receipt of Bruton's tyrosine kinase (BTK) inhibitor therapy have a poor prognosis. KTE-X19, an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, may have benefit in patients with relapsed or refractory mantle-cell lymphoma.
7754. Trends in U.S. Burden of Clostridioides difficile Infection and Outcomes.
作者: Alice Y Guh.;Yi Mu.;Lisa G Winston.;Helen Johnston.;Danyel Olson.;Monica M Farley.;Lucy E Wilson.;Stacy M Holzbauer.;Erin C Phipps.;Ghinwa K Dumyati.;Zintars G Beldavs.;Marion A Kainer.;Maria Karlsson.;Dale N Gerding.;L Clifford McDonald.; .
来源: N Engl J Med. 2020年382卷14期1320-1330页
Efforts to prevent Clostridioides difficile infection continue to expand across the health care spectrum in the United States. Whether these efforts are reducing the national burden of C. difficile infection is unclear.
7755. Multidrug-Resistant Bacterial Infections in U.S. Hospitalized Patients, 2012-2017.
作者: John A Jernigan.;Kelly M Hatfield.;Hannah Wolford.;Richard E Nelson.;Babatunde Olubajo.;Sujan C Reddy.;Natalie McCarthy.;Prabasaj Paul.;L Clifford McDonald.;Alex Kallen.;Anthony Fiore.;Michael Craig.;James Baggs.
来源: N Engl J Med. 2020年382卷14期1309-1319页
Multidrug-resistant (MDR) bacteria that are commonly associated with health care cause a substantial health burden. Updated national estimates for this group of pathogens are needed to inform public health action.
7756. Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding.
作者: James Y W Lau.;Yuanyuan Yu.;Raymond S Y Tang.;Heyson C H Chan.;Hon-Chi Yip.;Shannon M Chan.;Sally W Y Luk.;Sunny H Wong.;Louis H S Lau.;Rashid N Lui.;Ting T Chan.;Joyce W Y Mak.;Francis K L Chan.;Joseph J Y Sung.
来源: N Engl J Med. 2020年382卷14期1299-1308页
It is recommended that patients with acute upper gastrointestinal bleeding undergo endoscopy within 24 hours after gastroenterologic consultation. The role of endoscopy performed within time frames shorter than 24 hours has not been adequately defined.
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