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7463. Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial.
作者: Joanne R Chalmers.;Rachel H Haines.;Lucy E Bradshaw.;Alan A Montgomery.;Kim S Thomas.;Sara J Brown.;Matthew J Ridd.;Sandra Lawton.;Eric L Simpson.;Michael J Cork.;Tracey H Sach.;Carsten Flohr.;Eleanor J Mitchell.;Richard Swinden.;Stella Tarr.;Susan Davies-Jones.;Nicola Jay.;Maeve M Kelleher.;Michael R Perkin.;Robert J Boyle.;Hywel C Williams.; .
来源: Lancet. 2020年395卷10228期962-972页
Skin barrier dysfunction precedes eczema development. We tested whether daily use of emollient in the first year could prevent eczema in high-risk children.
7467. Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.
作者: Charles Calisher.;Dennis Carroll.;Rita Colwell.;Ronald B Corley.;Peter Daszak.;Christian Drosten.;Luis Enjuanes.;Jeremy Farrar.;Hume Field.;Josie Golding.;Alexander Gorbalenya.;Bart Haagmans.;James M Hughes.;William B Karesh.;Gerald T Keusch.;Sai Kit Lam.;Juan Lubroth.;John S Mackenzie.;Larry Madoff.;Jonna Mazet.;Peter Palese.;Stanley Perlman.;Leo Poon.;Bernard Roizman.;Linda Saif.;Kanta Subbarao.;Mike Turner.
来源: Lancet. 2020年395卷10226期e42-e43页 7468. Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial.
作者: Håvard Ove Skjerven.;Eva Maria Rehbinder.;Riyas Vettukattil.;Marissa LeBlanc.;Berit Granum.;Guttorm Haugen.;Gunilla Hedlin.;Linn Landrø.;Benjamin J Marsland.;Knut Rudi.;Kathrine Dønvold Sjøborg.;Cilla Söderhäll.;Anne Cathrine Staff.;Kai-Håkon Carlsen.;Anna Asarnoj.;Karen Eline Stensby Bains.;Oda C Lødrup Carlsen.;Kim M Advocaat Endre.;Peder Annæus Granlund.;Johanne Uthus Hermansen.;Hrefna Katrín Gudmundsdóttir.;Katarina Hilde.;Geir Håland.;Ina Kreyberg.;Inge Christoffer Olsen.;Caroline-Aleksi Olsson Mägi.;Live Solveig Nordhagen.;Carina Madelen Saunders.;Ingebjørg Skrindo.;Sandra G Tedner.;Magdalena R Værnesbranden.;Johanna Wiik.;Christine Monceyron Jonassen.;Björn Nordlund.;Karin C Lødrup Carlsen.
来源: Lancet. 2020年395卷10228期951-961页
Skin emollients applied during early infancy could prevent atopic dermatitis, and early complementary food introduction might reduce food allergy in high-risk infants. The study aimed to determine if either regular skin emollients applied from 2 weeks of age, or early complementary feeding introduced between 12 and 16 weeks of age, reduced development of atopic dermatitis by age 12 months in the general infant population.
7469. Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.
作者: Sarah Fidler.;Wolfgang Stöhr.;Matt Pace.;Lucy Dorrell.;Andrew Lever.;Sarah Pett.;Sabine Kinloch-de Loes.;Julie Fox.;Amanda Clarke.;Mark Nelson.;John Thornhill.;Maryam Khan.;Axel Fun.;Mikaila Bandara.;Damian Kelly.;Jakub Kopycinski.;Tomáš Hanke.;Hongbing Yang.;Rachel Bennett.;Margaret Johnson.;Bonnie Howell.;Richard Barnard.;Guoxin Wu.;Steve Kaye.;Mark Wills.;Abdel Babiker.;John Frater.; .
来源: Lancet. 2020年395卷10227期888-898页
Antiretroviral therapy (ART) cannot cure HIV infection because of a persistent reservoir of latently infected cells. Approaches that force HIV transcription from these cells, making them susceptible to killing-termed kick and kill regimens-have been explored as a strategy towards an HIV cure. RIVER is the first randomised trial to determine the effect of ART-only versus ART plus kick and kill on markers of the HIV reservoir.
7471. A future for the world's children? A WHO-UNICEF-Lancet Commission.
作者: Helen Clark.;Awa Marie Coll-Seck.;Anshu Banerjee.;Stefan Peterson.;Sarah L Dalglish.;Shanthi Ameratunga.;Dina Balabanova.;Maharaj Kishan Bhan.;Zulfiqar A Bhutta.;John Borrazzo.;Mariam Claeson.;Tanya Doherty.;Fadi El-Jardali.;Asha S George.;Angela Gichaga.;Lu Gram.;David B Hipgrave.;Aku Kwamie.;Qingyue Meng.;Raúl Mercer.;Sunita Narain.;Jesca Nsungwa-Sabiiti.;Adesola O Olumide.;David Osrin.;Timothy Powell-Jackson.;Kumanan Rasanathan.;Imran Rasul.;Papaarangi Reid.;Jennifer Requejo.;Sarah S Rohde.;Nigel Rollins.;Magali Romedenne.;Harshpal Singh Sachdev.;Rana Saleh.;Yusra R Shawar.;Jeremy Shiffman.;Jonathon Simon.;Peter D Sly.;Karin Stenberg.;Mark Tomlinson.;Rajani R Ved.;Anthony Costello.
来源: Lancet. 2020年395卷10224期605-658页 7478. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout.
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