7148. Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome (POPular AGE): the randomised, open-label, non-inferiority trial.
作者: Marieke Gimbel.;Khalid Qaderdan.;Laura Willemsen.;Rik Hermanides.;Thomas Bergmeijer.;Evelyn de Vrey.;Ton Heestermans.;Melvyn Tjon Joe Gin.;Reinier Waalewijn.;Sjoerd Hofma.;Frank den Hartog.;Wouter Jukema.;Clemens von Birgelen.;Michiel Voskuil.;Johannes Kelder.;Vera Deneer.;Jurriën Ten Berg.
来源: Lancet. 2020年395卷10233期1374-1381页
Current guidelines recommend potent platelet inhibition with ticagrelor or prasugrel in patients after an acute coronary syndrome. However, data about optimal platelet inhibition in older patients are scarce. We aimed to investigate the safety and efficacy of clopidogrel compared with ticagrelor or prasugrel in older patients with non-ST-elevation acute coronary syndrome (NSTE-ACS).
7149. Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial.
作者: Michelle S Hsiang.;Henry Ntuku.;Kathryn W Roberts.;Mi-Suk Kang Dufour.;Brooke Whittemore.;Munyaradzi Tambo.;Patrick McCreesh.;Oliver F Medzihradsky.;Lisa M Prach.;Griffith Siloka.;Noel Siame.;Cara Smith Gueye.;Leah Schrubbe.;Lindsey Wu.;Valerie Scott.;Sofonias Tessema.;Bryan Greenhouse.;Erica Erlank.;Lizette L Koekemoer.;Hugh J W Sturrock.;Agnes Mwilima.;Stark Katokele.;Petrina Uusiku.;Adam Bennett.;Jennifer L Smith.;Immo Kleinschmidt.;Davis Mumbengegwi.;Roly Gosling.
来源: Lancet. 2020年395卷10233期1361-1373页
In low malaria-endemic settings, screening and treatment of individuals in close proximity to index cases, also known as reactive case detection (RACD), is practised for surveillance and response. However, other approaches could be more effective for reducing transmission. We aimed to evaluate the effectiveness of reactive focal mass drug administration (rfMDA) and reactive focal vector control (RAVC) in the low malaria-endemic setting of Zambezi (Namibia).
7154. Bodily distribution of projectile injuries in Chilean protests.
作者: Pablo Cox.;Rodrigo Riveros.;Camila Leiva.;Yuri Carvajal.;Pablo Fuentes.;Jaime Recasens.;Alvaro Covarrubias.;Francisco Torres.;Daniel Ramírez.;Marcelo Verdugo.;Pablo Muñoz.
来源: Lancet. 2020年395卷10233期1341-1342页 |