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7041. Single Ring Isolation With Inferior Line Sparing for Atrial Fibrillation: A Proof-of-Concept Study.
作者: Anand Thiyagarajah.;Rajiv Mahajan.;Shinsuke Iwai.;Andrew Griffin.;Ricardo S Mishima.;Dominik Linz.;Mehrdad Emami.;Kadhim Kadhim.;Catherine J O'Shea.;Melissa E Middeldorp.;Dennis H Lau.;Prashanthan Sanders.
来源: Circ Arrhythm Electrophysiol. 2021年14卷4期e009552页 7042. New Approach for Atrioventricular Conduction Modulation by Ablation at a Distance From the Atrioventricular Node: Role in Nonpharmacologic Rate Control of Atrial Tachyarrhythmias.
作者: José Luis Ibáñez Criado.;Alicia Ibáñez Criado.;Teresa Barrio-López.;Thomas Brouzet.;Eduardo Castellanos.;Mercedes Ortiz.;Jessica Sánchez-Quiñones.;Amaya Garcia-Fernández.;Pablo Ramos-Ruiz.;Santiago Heras.;Raquel Ajo Ferrer.;Maria Ajo Ferrer.;Maria Rico.;Juan Antonio Quiles.;Francisco Sogorb-Garri.;Juan Gabriel Martínez Martínez.;Jesús Almendral.
来源: Circ Arrhythm Electrophysiol. 2021年14卷4期e009550页 7044. Template Beat: A Novel Marker for Left Bundle Branch Capture During Physiological Pacing.
作者: Shunmuga Sundaram Ponnusamy.;Vithiya Ganesan.;Thabish Syed.;Suryakumar Balasubramanian.;Pugazhendhi Vijayaraman.
来源: Circ Arrhythm Electrophysiol. 2021年14卷4期e009677页 7045. Evolving Cardiac Electrical Therapies for Advanced Heart Failure Patients.
作者: Zain I Sharif.;Vincent Galand.;William J Hucker.;Jagmeet P Singh.
来源: Circ Arrhythm Electrophysiol. 2021年14卷4期e009668页
Symptomatic heart failure (HF) patients despite optimal medical therapy and advances such as invasive hemodynamic monitoring remain challenging to manage. While cardiac resynchronization therapy remains a highly effective therapy for a subset of HF patients with wide QRS, a majority of symptomatic HF patients are poor candidates for such. Recently, cardiac contractility modulation, neuromodulation based on carotid baroreceptor stimulation, and phrenic nerve stimulation have been approved by the US Food and Drug Administration and are emerging as therapeutic options for symptomatic HF patients. This state-of-the-art review examines the role of these evolving electrical therapies in advanced HF.
7046. Electrophysiological Characteristics of Atrial Tachycardia After Mitral Valve Surgery via a Superior Transseptal Approach.
作者: Yasuyuki Egami.;Kohei Ukita.;Akito Kawamura.;Hitoshi Nakamura.;Yutaka Matsuhiro.;Koji Yasumoto.;Masaki Tsuda.;Naotaka Okamoto.;Akihiro Tanaka.;Yasuharu Matsunaga-Lee.;Masamichi Yano.;Ryu Shutta.;Masami Nishino.;Jun Tanouchi.
来源: Circ Arrhythm Electrophysiol. 2021年14卷4期e009437页 7047. Cost-Effectiveness of Hypertension Treatment by Pharmacists in Black Barbershops.
作者: Kelsey B Bryant.;Andrew E Moran.;Dhruv S Kazi.;Yiyi Zhang.;Joanne Penko.;Natalia Ruiz-Negrón.;Pamela Coxson.;Ciantel A Blyler.;Kathleen Lynch.;Laura P Cohen.;Gabriel S Tajeu.;Valy Fontil.;Norma B Moy.;Joseph E Ebinger.;Florian Rader.;Kirsten Bibbins-Domingo.;Brandon K Bellows.
来源: Circulation. 2021年143卷24期2384-2394页
In LABBPS (Los Angeles Barbershop Blood Pressure Study), pharmacist-led hypertension care in Los Angeles County Black-owned barbershops significantly improved blood pressure control in non-Hispanic Black men with uncontrolled hypertension at baseline. In this analysis, 10-year health outcomes and health care costs of 1 year of the LABBPS intervention versus control are projected.
7048. Oxygen Pathway Limitations in Patients With Chronic Thromboembolic Pulmonary Hypertension.
作者: Erin J Howden.;Sergio Ruiz-Carmona.;Mathias Claeys.;Ruben De Bosscher.;Rik Willems.;Bart Meyns.;Tom Verbelen.;Geert Maleux.;Laurent Godinas.;Catharina Belge.;Jan Bogaert.;Piet Claus.;Andre La Gerche.;Marion Delcroix.;Guido Claessen.
来源: Circulation. 2021年143卷21期2061-2073页
Exertional intolerance is a limiting and often crippling symptom in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Traditionally the pathogenesis has been attributed to central factors, including ventilation/perfusion mismatch, increased pulmonary vascular resistance, and right heart dysfunction and uncoupling. Pulmonary endarterectomy and balloon pulmonary angioplasty provide substantial improvement of functional status and hemodynamics. However, despite normalization of pulmonary hemodynamics, exercise capacity often does not return to age-predicted levels. By systematically evaluating the oxygen pathway, we aimed to elucidate the causes of functional limitations in patients with CTEPH before and after pulmonary vascular intervention.
7049. Prevention of Viridans Group Streptococcal Infective Endocarditis: A Scientific Statement From the American Heart Association.
作者: Walter R Wilson.;Michael Gewitz.;Peter B Lockhart.;Ann F Bolger.;Daniel C DeSimone.;Dhruv S Kazi.;David J Couper.;Andrea Beaton.;Catherine Kilmartin.;Jose M Miro.;Craig Sable.;Mary Anne Jackson.;Larry M Baddour.; .
来源: Circulation. 2021年143卷20期e963-e978页
In 2007, the American Heart Association published updated evidence-based guidelines on the recommended use of antibiotic prophylaxis to prevent viridans group streptococcal (VGS) infective endocarditis (IE) in cardiac patients undergoing invasive procedures. The 2007 guidelines significantly scaled back the underlying conditions for which antibiotic prophylaxis was recommended, leaving only 4 categories thought to confer the highest risk of adverse outcome. The purpose of this update is to examine interval evidence of the acceptance and impact of the 2007 recommendations on VGS IE and, if needed, to make revisions based on this evidence.
7050. Biomarker-Based Risk Prediction With the ABC-AF Scores in Patients With Atrial Fibrillation Not Receiving Oral Anticoagulation.
作者: Alexander P Benz.;Ziad Hijazi.;Johan Lindbäck.;Stuart J Connolly.;John W Eikelboom.;Jonas Oldgren.;Agneta Siegbahn.;Lars Wallentin.
来源: Circulation. 2021年143卷19期1863-1873页
The novel ABC (Age, Biomarkers, Clinical History) scores outperform traditional risk scores for stroke, major bleeding, and death in patients with atrial fibrillation (AF) receiving oral anticoagulation. To refine their utility, the ABC-AF scores needed to be validated in patients not receiving oral anticoagulation.
7051. Treatment-Related Changes in Left Atrial Structure in Atrial Fibrillation: Findings From the CABANA Imaging Substudy.
作者: Maryam E Rettmann.;David R Holmes.;Kristi H Monahan.;Jerome F Breen.;Tristram D Bahnson.;Daniel B Mark.;Jeanne E Poole.;Alicia M Ellis.;Adam P Silverstein.;Hussein R Al-Khalidi.;Kerry L Lee.;Richard A Robb.;Douglas L Packer.; .
来源: Circ Arrhythm Electrophysiol. 2021年14卷5期e008540页
[Figure: see text].
7052. Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis.
作者: Matthew W Segar.;Byron C Jaeger.;Kershaw V Patel.;Vijay Nambi.;Chiadi E Ndumele.;Adolfo Correa.;Javed Butler.;Alvin Chandra.;Colby Ayers.;Shreya Rao.;Alana A Lewis.;Laura M Raffield.;Carlos J Rodriguez.;Erin D Michos.;Christie M Ballantyne.;Michael E Hall.;Robert J Mentz.;James A de Lemos.;Ambarish Pandey.
来源: Circulation. 2021年143卷24期2370-2383页
Heart failure (HF) risk and the underlying risk factors vary by race. Traditional models for HF risk prediction treat race as a covariate in risk prediction and do not account for significant parameters such as cardiac biomarkers. Machine learning (ML) may offer advantages over traditional modeling techniques to develop race-specific HF risk prediction models and to elucidate important contributors of HF development across races.
7053. Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments.
作者: Mary F Feitosa.;Allison L Kuipers.;Mary K Wojczynski.;Lihua Wang.;Emma Barinas-Mitchell.;Alexander M Kulminski.;Bharat Thyagarajan.;Joseph H Lee.;Thomas Perls.;Kaare Christensen.;Anne B Newman.;Joseph M Zmuda.;Michael A Province.
来源: Circ Genom Precis Med. 2021年14卷3期e003201页
Polygenic risk scores (PRS) for coronary heart disease (CHD) may contribute to assess the overall risk of CHD. We evaluated how PRS may influence CHD risk when the distribution of age-at-onset, sex, and family health history differ significantly.
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