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6941. Burden of illness among subgroups of patients with primary Sjögren's syndrome and systemic involvement.
作者: Kerry Gairy.;Claudia Knight.;Papa Anthony.;Ben Hoskin.
来源: Rheumatology (Oxford). 2021年60卷4期1871-1881页
To describe how patients with primary SS (pSS) and systemic organ involvement are classified and clustered in routine practice.
6942. Psoriatic arthritis is associated with adverse body composition predictive of greater coronary heart disease and type 2 diabetes propensity - a cross-sectional study.
作者: Lyn D Ferguson.;Jennifer Linge.;Olof Dahlqvist Leinhard.;Rosemary Woodward.;Pauline Hall Barrientos.;Giles Roditi.;Aleksandra Radjenovic.;Iain B McInnes.;Stefan Siebert.;Naveed Sattar.
来源: Rheumatology (Oxford). 2021年60卷4期1858-1862页
To compare body composition in PsA with metabolic disease free (MDF) controls and type 2 diabetes and assess body-composition predicted propensity for cardiometabolic disease.
6943. Focal small bowel thrombotic microvascular injury in COVID-19 mediated by the lectin complement pathway masquerading as lupus enteritis.
作者: Benjamin Plotz.;Rochelle Castillo.;Jonathan Melamed.;Cynthia Magro.;Pamela Rosenthal.;H Michael Belmont.
来源: Rheumatology (Oxford). 2021年60卷2期e61-e63页 6944. Identification and prediction of novel classes of long-term disease trajectories for patients with juvenile dermatomyositis using growth mixture models.
作者: Claire T Deakin.;Charalampia Papadopoulou.;Liza J McCann.;Neil Martin.;Muthana Al-Obaidi.;Sandrine Compeyrot-Lacassagne.;Clarissa A Pilkington.;Sarah L Tansley.;Neil J McHugh.;Lucy R Wedderburn.;Bianca L De Stavola.; .
来源: Rheumatology (Oxford). 2021年60卷4期1891-1901页
Uncertainty around clinical heterogeneity and outcomes for patients with JDM represents a major burden of disease and a challenge for clinical management. We sought to identify novel classes of patients having similar temporal patterns in disease activity and relate them to baseline clinical features.
6945. US rheumatologists' beliefs and knowledge about biosimilars: a survey.
We sought to evaluate perceptions of biosimilar products among US rheumatologists who prescribe TNF-α inhibitors, given that 10 TNF-α inhibitor biosimilars and two rituximab biosimilars have Food and Drug Administration (FDA) approval.
6948. Laser speckle contrast analysis predicts major vascular complications and mortality of patients with systemic sclerosis.
作者: Antonietta Gigante.;Annalisa Villa.;Edoardo Rosato.
来源: Rheumatology (Oxford). 2021年60卷4期1850-1857页
The aim of study was to evaluate peripheral blood perfusion and the proximal-distal gradient (PDG) of the hands as biomarkers of SSc major vascular complications (digital ulcers, pulmonary arterial hypertension, scleroderma renal crisis) and mortality by laser speckle contrast analysis.
6949. Long-term maintenance rituximab for ANCA-associated vasculitis: relapse and infection prediction models.
作者: Mark E McClure.;Yajing Zhu.;Rona M Smith.;Seerapani Gopaluni.;Joanna Tieu.;Tasneem Pope.;Karl Emil Kristensen.;David R W Jayne.;Jessica Barrett.;Rachel B Jones.
来源: Rheumatology (Oxford). 2021年60卷3期1491-1501页
Following a maintenance course of rituximab (RTX) for ANCA-associated vasculitis (AAV), relapses occur on cessation of therapy, and further dosing is considered. This study aimed to develop relapse and infection risk prediction models to help guide decision making regarding extended RTX maintenance therapy.
6950. Response to placebo in non-renal, non-neuropsychiatric systemic lupus erythematosus: a systematic review and pooled analysis.
作者: Konstantinos Tselios.;Laura Wakani.;Dafna D Gladman.;Jiandong Su.;Murray B Urowitz.
来源: Rheumatology (Oxford). 2021年60卷1期73-80页
Most randomized controlled trials (RCTs) in SLE have failed to reach their respective end points, with the rates of response to placebo (plus standard-of-care treatment) being unexpectedly high. The aim of this systematic review was to quantify the response to placebo in non-renal, non-neuropsychiatric lupus.
6951. Systematic review and meta-analysis of epidemiological studies on the association of occupational exposure to free crystalline silica and systemic lupus erythematosus.
作者: Alberto Morotti.;Irena Sollaku.;Simona Catalani.;Franco Franceschini.;Ilaria Cavazzana.;Micaela Fredi.;Emma Sala.;Giuseppe De Palma.
来源: Rheumatology (Oxford). 2021年60卷1期81-91页
Some evidence suggests that exposure to free crystalline silica may contribute to the risk of developing SLE. A systematic search was carried out for all published epidemiological studies concerning this association. A meta-analysis was conducted on relevant studies.
6952. European League Against Rheumatism (EULAR) recommendations and EULAR/American College of Rheumatology criteria-documenting progress in lupus.
作者: Martin Aringer.;Maria G Tektonidou.;Dimitrios Boumpas.;Frédéric Houssiau.
来源: Rheumatology (Oxford). 2021年60卷6期2976-2978页 6954. Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America.
作者: Gulnara Mamyrova.;Takayuki Kishi.;Min Shi.;Ira N Targoff.;Adam M Huber.;Rodolfo V Curiel.;Frederick W Miller.;Lisa G Rider.; .
来源: Rheumatology (Oxford). 2021年60卷4期1839-1849页
Myositis-specific autoantibodies have defined distinct phenotypes of patients with juvenile myositis (JIIM). We assessed the frequency and clinical significance of anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody-associated JIIM in a North American registry.
6955. How COVID-19 is changing rheumatology clinical practice.
作者: Eloisa Bonfá.;Laure Gossec.;David A Isenberg.;Zhanguo Li.;Soumya Raychaudhuri.
来源: Nat Rev Rheumatol. 2021年17卷1期11-15页
The emergence of COVID-19 in early 2020 led to unprecedented changes to rheumatology clinical practice worldwide, including the closure of research laboratories, the restructuring of hospitals and the rapid transition to virtual care. As governments sought to slow and contain the spread of the disease, rheumatologists were presented with the difficult task of managing risks, to their patients as well as to themselves, while learning and implementing new systems for remote health care. Consequently, the COVID-19 pandemic led to a transformation in health infrastructures and telemedicine that could become powerful tools for rheumatologists, despite having some limitations. In this Viewpoint, five experts from different regions discuss their experiences of the pandemic, including the most challenging aspects of this unexpected transition, the advantages and limitations of virtual visits, and potential opportunities going forward.
6957. Dendritic cell integrin expression patterns regulate inflammation in the rheumatoid arthritis joint.
作者: Leonie Schittenhelm.;Jamie Robertson.;Arthur G Pratt.;Catharien M Hilkens.;Vicky L Morrison.
来源: Rheumatology (Oxford). 2021年60卷3期1533-1542页
Immune dysregulation contributes to the development of RA. Altered surface expression patterns of integrin adhesion receptors by immune cells is one mechanism by which this may occur. We investigated the role of β2 integrin subunits CD11a and CD11b in dendritic cell (DC) subsets of RA patients.
6958. Cost-effectiveness of on-site musculoskeletal ultrasound in an outpatient rheumatology clinic.
作者: Carlos Acebes.;Laura Rubio.;Almudena Román.;Antonio Herrero.;Javier Arcos.
来源: Rheumatology (Oxford). 2021年60卷4期1832-1838页
To evaluate the impact of the routine use of musculoskeletal ultrasound (MSUS) in rheumatology clinics by comparing one clinic with on-site MSUS (REU 1) and four clinics without this resource, which need to refer patients for the MSUS exams (REU 2-5).
6959. Temporal artery compression sonography for the diagnosis of giant cell arteritis in elderly patients with acute ocular arterial occlusions.
作者: Michael Czihal.;Anton Köhler.;Christian Lottspeich.;Ilaria Prearo.;Ulrich Hoffmann.;Hendrik Schulze-Koops.;Siegfried G Priglinger.;Marc J Mackert.;Claudia Dechant.
来源: Rheumatology (Oxford). 2021年60卷5期2190-2196页
To validate cut-off values of quantitative high-resolution temporal artery compression sonography (TCS) for the diagnosis of cranial GCA (cGCA) in patients with acute arterial ocular occlusions and in an independent control group.
6960. The dysregulation of monocyte subpopulations in individuals at risk of developing rheumatoid arthritis.
作者: Klára Prajzlerová.;Olga Kryštůfková.;Martin Komarc.;Heřman Mann.;Hana Hulejová.;Nora Petrovská.;Monika Gregová.;Petra Hánová.;Karel Pavelka.;Jiří Vencovský.;Ladislav Šenolt.;Mária Filková.
来源: Rheumatology (Oxford). 2021年60卷4期1823-1831页
Individuals carrying antibodies against citrullinated proteins (ACPA) are at high risk of developing RA. EULAR provided a clinical definition of individuals with arthralgia suspicious for progression to RA (clinically suspect arthralgia, CSA). The alteration of monocyte subpopulations in patients with established RA has been previously described. We analysed peripheral blood monocyte subpopulations in individuals with arthralgia at risk of RA.
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