392. Remibrutinib in Chronic Spontaneous Urticaria.
作者: Martin Metz.;Ana Giménez-Arnau.;Michihiro Hide.;Mark Lebwohl.;Giselle Mosnaim.;Sarbjit Saini.;Gordon Sussman.;Robert Szalewski.;Sibylle Haemmerle.;Karine Lheritier.;El-Djouher Martzloff.;Noriko Seko.;Pengpeng Wang.;Artem Zharkov.;Marcus Maurer.; .; .; .
来源: N Engl J Med. 2025年392卷10期984-994页
Chronic spontaneous urticaria is an idiopathic syndrome defined by recurring itch, hives, or angioedema (or a combination of these symptoms) for more than 6 weeks. Remibrutinib, an oral, highly selective Bruton's tyrosine kinase inhibitor, showed efficacy and favorable safety in phase 2b trials. Data from phase 3 trials are needed.
393. Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis.
作者: Lenka A Vodstrcil.;Erica L Plummer.;Christopher K Fairley.;Jane S Hocking.;Matthew G Law.;Kathy Petoumenos.;Deborah Bateson.;Gerald L Murray.;Basil Donovan.;Eric P F Chow.;Marcus Y Chen.;John Kaldor.;Catriona S Bradshaw.; .
来源: N Engl J Med. 2025年392卷10期947-957页
Bacterial vaginosis affects one third of reproductive-aged women, and recurrence is common. Evidence of sexual exchange of bacterial vaginosis-associated organisms between partners suggests that male-partner treatment may increase the likelihood of cure.
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