3841. Financial Justification for Interventional Pulmonology Programs: Terminology and Programmatic Models.
作者: Amit K Mahajan.;Jennifer Bautista.;Erin Hodson.;Sandeep J Khandhar.;Erik Folch.;Susan Carroll.;Steve Narang.
来源: Chest. 2020年158卷3期1115-1121页
Interventional pulmonology programs provide clinical benefit to patients and are financially sustainable. To appreciate and illustrate the economic value of interventional pulmonology programs to hospital systems, physicians must have an understanding of basic health-care finance. Total revenue, adjusted gross revenue, contribution margin, variable direct costs, and indirect costs are terms that are essential for understanding the finances of bronchoscopy. Command of such vocabulary and its application is crucial for interventional pulmonologists to successfully establish financially sustainable bronchoscopy programs. Two significant features of an economically sustainable bronchoscopy program are high procedural volume and low direct cost per case. Interventional pulmonology programs are valuable to the patients being served and hospitals as a whole. Consideration of the various factors needed to maintain financial sustainability is essential to improve the quality of care for patients because the cost of care remains a critical driver in defining value.
3842. Who May Benefit From Diuretics in OSA?: A Propensity Score-Match Observational Study.
作者: Bruno Revol.;Ingrid Jullian-Desayes.;Sébastien Bailly.;Renaud Tamisier.;Yves Grillet.;Marc Sapène.;Marie Joyeux-Faure.;Jean-Louis Pépin.; .
来源: Chest. 2020年158卷1期359-364页
Diuretics have been reported as effective for reducing OSA severity by preventing fluid retention and reducing rostral fluid shift. The benefit of diuretics might vary depending on the OSA clinical phenotype and comorbidities. To test this hypothesis, we conducted a propensity score-matched cohort analysis of data from the French national sleep apnea registry "Observatoire Sommeil de la Fédération de Pneumologie."
3843. Ambulatory Oxygen in Fibrotic Interstitial Lung Disease: A Pilot, Randomized, Triple-Blinded, Sham-Controlled Trial.
作者: Yet H Khor.;Anne E Holland.;Nicole S L Goh.;Belinda R Miller.;Ross Vlahos.;Steven Bozinovski.;Aroub Lahham.;Ian Glaspole.;Christine F McDonald.
来源: Chest. 2020年158卷1期234-244页
Despite a lack of evidence, ambulatory oxygen therapy is frequently prescribed for patients with interstitial lung disease (ILD) and exertional desaturation. Patients often prefer portable oxygen concentrators to oxygen cylinders. This study aimed to examine the feasibility of conducting a clinical trial of ambulatory oxygen delivered via portable concentrators in patients with ILD.
3844. Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects.
作者: Ruyang Zhang.;Chao Chen.;Xuesi Dong.;Sipeng Shen.;Linjing Lai.;Jieyu He.;Dongfang You.;Lijuan Lin.;Ying Zhu.;Hui Huang.;Jiajin Chen.;Liangmin Wei.;Xin Chen.;Yi Li.;Yichen Guo.;Weiwei Duan.;Liya Liu.;Li Su.;Andrea Shafer.;Thomas Fleischer.;Maria Moksnes Bjaanæs.;Anna Karlsson.;Maria Planck.;Rui Wang.;Johan Staaf.;Åslaug Helland.;Manel Esteller.;Yongyue Wei.;Feng Chen.;David C Christiani.
来源: Chest. 2020年158卷2期808-819页
DNA methylation and gene expression are promising biomarkers of various cancers, including non-small cell lung cancer (NSCLC). Besides the main effects of biomarkers, the progression of complex diseases is also influenced by gene-gene (G×G) interactions.
3845. Simulation Training for Critical Care Airway Management: Assessing Translation to Clinical Practice Using a Small Video-Recording Device.
作者: Ronak T Shah.;Mina R Makaryus.;Rohit Kumar.;Effie Singas.;Paul H Mayo.
来源: Chest. 2020年158卷1期272-278页
Critical care airway management (CCAM) is a key skill for critical care physicians. Simulation-based training (SBT) may be an effective modality in training intensivists in CCAM.
3846. Alternative Splicing of the Cardiac Sodium Channel in Pulmonary Arterial Hypertension.
作者: Debasree Banerjee.;Tom N Grammatopoulos.;Amy Palmisciano.;James R Klinger.;Ipsita Krishnan.;Mary Whittenhall.;Anyu Zhou.;Samuel Dudley.;Corey E Ventetuolo.
来源: Chest. 2020年158卷2期735-738页 3847. Outcomes of Pulmonary Arterial Hypertension Are Improved in a Specialty Care Center.
作者: Hongyang Pi.;Chad M Kosanovich.;Adam Handen.;Michael Tao.;Jacqueline Visina.;Gabrielle Vanspeybroeck.;Marc A Simon.;Michael G Risbano.;Aken Desai.;Michael A Mathier.;Belinda N Rivera-Lebron.;Quyen Nguyen.;Jennifer Kliner.;Mehdi Nouraie.;Stephen Y Chan.
来源: Chest. 2020年158卷1期330-340页
Pulmonary arterial hypertension (PAH) is characterized by elevated pulmonary arterial pressures and is managed by vasodilator therapies. Current guidelines encourage PAH management in specialty care centers (SCCs), but evidence is sparse regarding improvement in clinical outcomes and correlation to vasodilator use with referral.
3848. Use of Combined Do-Not-Resuscitate/Do-Not Intubate Orders Without Documentation of Intubation Preferences: A Retrospective Observational Study at an Academic Level 1 Trauma Center Code Status and Intubation Preferences.
Combining orders for do-not-resuscitate (DNR) for cardiac arrest with do-not-intubate (DNI) orders into a DNR/DNI code status is not evidence-based practice and may violate patient autonomy and informed consent when providers discuss intubation only in the context of CPR.
3849. Chronic Cough Due to Stable Chronic Bronchitis: CHEST Expert Panel Report.
作者: Mark A Malesker.;Priscilla Callahan-Lyon.;J Mark Madison.;Belinda Ireland.;Richard S Irwin.; .
来源: Chest. 2020年158卷2期705-718页
Chronic cough due to chronic bronchitis (CB) causes significant impairment in quality of life, and effective treatment strategies are needed. We conducted a systematic review on the management of chronic cough due to CB to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic.
3850. The Association Between Air Pollution and Hospitalization of Patients With Idiopathic Pulmonary Fibrosis in Chile: A Daily Time Series Analysis.
Idiopathic pulmonary fibrosis (IPF) causes progressive dyspnea, hypoxemia, and death within a few years. Little is known about the effect of air pollution on disease exacerbations.
3851. Acute Cough Due to Acute Bronchitis in Immunocompetent Adult Outpatients: CHEST Expert Panel Report.
作者: Maeve P Smith.;Mark Lown.;Sonal Singh.;Belinda Ireland.;Adam T Hill.;Jeffrey A Linder.;Richard S Irwin.; .
来源: Chest. 2020年157卷5期1256-1265页
Evidence for the diagnosis and management of cough due to acute bronchitis in immunocompetent adult outpatients was reviewed as an update to the 2006 "Chronic Cough Due to Acute Bronchitis: American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines."
3852. Diagnosis of EVALI: General Approach and the Role of Bronchoscopy.
作者: Scott K Aberegg.;Sean D Maddock.;Denitza P Blagev.;Sean J Callahan.
来源: Chest. 2020年158卷2期820-827页
A 23-year-old man arrives at the ED with a 3-week history of dyspnea, dry cough, fevers, and night sweats. Two weeks previously, he was evaluated in an outpatient clinic and given a course of azithromycin for presumed infectious pneumonia. His symptoms did not improve, and he was seen 1 week later in an urgent care center and given a prescription for doxycycline, which he has been taking without improvement. He states that he feels miserable, has severe nausea and vomiting, and has not eaten in several days. His only medical history is childhood asthma. He reports no surgeries and takes no medications. He has no risk factors for HIV, does not smoke combustible cigarettes or use IV drugs, and has not recently traveled. Examination shows a room air saturation of 89%, a temperature of 38.3°C, and a respiratory rate of 22 breaths/min. Results of his examination are normal, and there are no rales or wheezing heard in the lungs. Chest radiograph shows bilateral, consolidative opacities. WBC count is 14,000, with left shift. Results of biochemistries are normal. Erythrocyte sedimentation rate is 104, and procalcitonin is 0.08. Urine toxicology screen is positive for tetrahydrocannabinol (THC). Asked specifically about vaping and e-cigarette use, he reports that he recently began using THC "carts" that his friend gets from an unknown supplier. What is the diagnosis and what additional steps are necessary to confirm it? Is bronchoscopy indicated?
3853. A Randomized, Double-Blind, Placebo-Controlled Study of Pulsed, Inhaled Nitric Oxide in Subjects at Risk of Pulmonary Hypertension Associated With Pulmonary Fibrosis.
作者: Steven D Nathan.;Kevin R Flaherty.;Marilyn K Glassberg.;Ganesh Raghu.;Jeffrey Swigris.;Roger Alvarez.;Neil Ettinger.;Jim Loyd.;Peter Fernandes.;Hunter Gillies.;Bo Kim.;Parag Shah.;Lisa Lancaster.
来源: Chest. 2020年158卷2期637-645页
The interstitial lung diseases include a variety of disorders, many of which are characterized by fibrotic changes (fILD). Of the fILDs, Idiopathic pulmonary fibrosis is the most common. Pulmonary hypertension (PH) frequently complicates fILD and is associated with impaired functional capability, lower physical activity, and significantly reduced life expectancy. There is no proven treatment for patients with fILD-PH. We report results from the first cohort of a phase 2b/3 trial with pulsed inhaled nitric oxide (iNO) in patients with fILD-PH.
3854. "High-Risk" Clinical and Inflammatory Clusters in COPD of Chinese Descent.
作者: Pei Yee Tiew.;Fanny Wai San Ko.;Jayanth Kumar Narayana.;Mau Ern Poh.;Huiying Xu.;Han Yee Neo.;Li-Cher Loh.;Choo Khoon Ong.;Micheál Mac Aogáin.;Jessica Han Ying Tan.;Nabilah Husna Kamaruddin.;Gerald Jiong Hui Sim.;Therese S Lapperre.;Mariko Siyue Koh.;David Shu Cheong Hui.;John Arputhan Abisheganaden.;Augustine Tee.;Krasimira Tsaneva-Atanasova.;Sanjay H Chotirmall.
来源: Chest. 2020年158卷1期145-156页
COPD is a heterogeneous disease demonstrating inter-individual variation. A high COPD prevalence in Chinese populations is described, but little is known about disease clusters and prognostic outcomes in the Chinese population across Southeast Asia. We aim to determine if clusters of Chinese patients with COPD exist and their association with systemic inflammation and clinical outcomes.
3855. Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS: Insights From the LUNG SAFE Study.
作者: Abhijit Duggal.;Emanuele Rezoagli.;Tài Pham.;Bairbre A McNicholas.;Eddy Fan.;Giacomo Bellani.;Gordon Rubenfeld.;Antonio M Pesenti.;John G Laffey.; .
来源: Chest. 2020年157卷6期1497-1505页
Adjunctive strategies are an important part of the management of ARDS. However, their application in clinical practice remains inconsistent.
3857. Better With Ultrasound: Detection of DVT.
作者: Ariel L Shiloh.;Christa McPhee.;Lewis Eisen.;Seth Koenig.;Scott J Millington.
来源: Chest. 2020年158卷3期1122-1127页
Ultrasound studies to detect DVT are traditionally performed and interpreted by sonographers and radiologists, respectively, but the growth of point-of-care ultrasound is putting this powerful tool in the hands of front-line physicians. Literature from ambulatory patients in the ED suggests this tool performs well in the hands of nonconventional users, and it is now being commonly deployed to aid in the management of critically ill patients. This article presents an approach for incorporating these tools into bedside practice, including illustrative figures and narrated video presentations to demonstrate the techniques described.
3858. Differences in Clinical Characteristics and Outcomes Between Men and Women With Idiopathic Pulmonary Fibrosis: A Multicenter Retrospective Cohort Study.
作者: Tanzira Zaman.;Teng Moua.;Eric Vittinghoff.;Jay H Ryu.;Harold R Collard.;Joyce S Lee.
来源: Chest. 2020年158卷1期245-251页
Idiopathic pulmonary fibrosis (IPF) is a disease with a male predominance. Prior data suggest that male sex is associated with disease progression and survival. The basis for this sex difference is unknown.
3859. Incorporating Medical Student Documentation Into the Billable Encounter: A Pragmatic Approach to Implementation of the 2018 Centers for Medicare & Medicaid Services Rule Revision.
In early 2018, the Centers for Medicare & Medicaid Services released the Medical Review of Evaluation and Management (E/M) Documentation, which allows supervising teaching physicians to rely on a medical student's documentation to support billing for E/M services. This change has potential to enhance education, clinical documentation quality, and the satisfaction of students, postgraduate trainees, and teaching physicians. However, its practical adoption presents many challenges that must be navigated successfully to realize these important goals in compliance with federal and local requirements, while avoiding unintended downstream problems. Implementation requires careful planning, policy creation, education, and monitoring, all with collaboration between institutional leaders, compliance and information technology professionals, educators, and learners. In this paper, we review the 2018 Centers for Medicare & Medicaid Services rule change, address common questions and potential impacts, outline practical workflows to meet the supervision requirement, and discuss steps for successful implementation.
3860. Patient-Centered, Guideline-Concordant Discussion and Management of Pulmonary Nodules.
Providing guideline-concordant management of pulmonary nodules can present challenges when a patient's anxiety about cancer or fear of invasive procedures colors judgment. The way in which providers discuss and make decisions about how to evaluate a pulmonary nodule can affect patient satisfaction, distress, and adherence to evaluation. This article discusses the complexity of tailoring patient-provider communication, decision-making, and implementation of guidelines for pulmonary nodule evaluation to the individual patient, emphasizing the importance of how information is conveyed and the value of listening to and addressing patients' concerns. We summarize the relevant guideline recommendations and literature, and provide two case scenarios to illustrate a patient-centered approach to discussing and managing pulmonary nodules from our perspectives as a pulmonologist and thoracic surgeon.
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