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3561. Baseline Characteristics and Progression of a Spectrum of Interstitial Lung Abnormalities and Disease in Rheumatoid Arthritis.
作者: Leticia Kawano-Dourado.;Tracy J Doyle.;Karina Bonfiglioli.;Márcio V Y Sawamura.;Renato H Nakagawa.;Fábio E Arimura.;Hye J Lee.;Diana Arrais de Souza Rangel.;Cleonice Bueno.;Carlos R R Carvalho.;Maria Laura Sabbag.;Camila Molina.;Ivan O Rosas.;Ronaldo A Kairalla.
来源: Chest. 2020年158卷4期1546-1554页
Interstitial lung abnormalities (ILA) and interstitial lung disease (ILD) are seen in up to 60% of individuals with rheumatoid arthritis (RA), some of which will progress to have a significant impact on morbidity and mortality rates. Better characterization of progressive interstitial changes and identification of risk factors that are associated with progression may enable earlier intervention and improved outcomes.
3562. Characteristics of Effective Teachers of Invasive Bedside Procedures: A Multi-institutional Qualitative Study.
作者: Diana J Kelm.;Jennifer L Ridgeway.;John T Ratelle.;Adam P Sawatsky.;Andrew J Halvorsen.;Alexander S Niven.;Anna Brady.;Margaret M Hayes.;Jakob I McSparron.;Kannan Ramar.;Thomas J Beckman.
来源: Chest. 2020年158卷5期2047-2057页
Faculty supervision of invasive bedside procedures (IBPs) in the ICU may enhance procedural education and ensure patient safety. However, there is limited research on teaching effectiveness in the ICU, and there are no best teaching practices regarding the supervision of IBPs.
3563. Effects of Anti-T2 Biologic Treatment on Lung Ventilation Evaluated by MRI in Adults With Prednisone-Dependent Asthma.
作者: Sarah Svenningsen.;Rachel L Eddy.;Melanie Kjarsgaard.;Grace Parraga.;Parameswaran Nair.
来源: Chest. 2020年158卷4期1350-1360页
The functional consequence of airway obstruction in asthma can be regionally measured using inhaled gas MRI. Ventilation defects visualized by MRI persist post-bronchodilator in patients with severe asthma with uncontrolled sputum eosinophilia and may be due to eosinophil-driven airway pathology that is responsive to "anti-T2" therapy.
3564. Effectiveness of an Opt-Out Electronic Heath Record-Based Tobacco Treatment Consult Service at an Urban Safety Net Hospital.
作者: Nicole Herbst.;Renda Soylemez Wiener.;Eric D Helm.;Charles O'Donnell.;Carmel Fitzgerald.;Carolina Wong.;Katia Bulekova.;Meg Waite.;Rebecca G Mishuris.;Hasmeena Kathuria.
来源: Chest. 2020年158卷4期1734-1741页
To address the burden of tobacco use in underserved populations, our safety net hospital developed a tobacco treatment intervention consisting of an "opt-out" electronic health record-based best practice alert + order set, which triggers consultation to an inpatient tobacco treatment consult (TTC) service for all hospitalized smokers.
3565. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for PD-L1 Testing in Non-small Cell Lung Cancer.
作者: Fabio Perrotta.;Matthew Nankivell.;Jana B Adizie.;Usman Maqsood.;Mohamed Elshafi.;Syeda Jafri.;Andrew D Lerner.;Ian Woolhouse.;Mohammed Munavvar.;Matthew Evison.;Richard Booton.;David R Baldwin.;Samuel M Janes.;Keith M Kerr.;Andrea Bianco.;Lonny Yarmus.;Neal Navani.
来源: Chest. 2020年158卷3期1230-1239页
Programmed death-ligand 1 (PD-L1) expression on cancer cells is a clinically important biomarker to select patients with non-small cell lung cancer (NSCLC) for treatment with programmed death-1/PD-L1 inhibitors. Clinical trials of immunotherapy in patients with NSCLC have required histologic evidence for PD-L1 testing; in clinical practice, cytologic samples commonly are acquired in patients with advanced disease.
3566. Mortality Risk Prediction in Amyopathic Dermatomyositis Associated With Interstitial Lung Disease: The FLAIR Model.
作者: Xinyue Lian.;Jing Zou.;Qiang Guo.;Sheng Chen.;Liangjing Lu.;Ran Wang.;Mengmeng Zhou.;Qiong Fu.;Yan Ye.;Chunde Bao.
来源: Chest. 2020年158卷4期1535-1545页
The prognosis of amyopathic dermatomyositis (ADM)-associated interstitial lung disease (ILD) is poor. A mortality risk score model is needed to predict survival in patients with ADM-ILD and to guide clinical treatment.
3567. Better With Ultrasound: Thoracic Ultrasound.
Ultrasound examination of the thorax is superior to chest radiograph or physical examination for diagnosing common conditions such as pneumonia, pulmonary edema, pleural effusion, and pneumothorax. The basic skill set is straightforward to learn, quick to perform, repeatable, and does not involve patient transport, harmful ionizing radiation, or waiting time. This paper outlines the basic building blocks that makeup a thoracic ultrasound examination, regardless of which specific scanning protocol is performed. Narrative videos and illustrative figures demonstrating these techniques are included.
3568. Key Highlights of the Canadian Thoracic Society's Position Statement on the Optimization of COPD Management During the Coronavirus Disease 2019 Pandemic.
作者: Mohit Bhutani.;Paul Hernandez.;Jean Bourbeau.;Gail Dechman.;Erika Penz.;Raymond Aceron.;Marla Beauchamp.;Joshua Wald.;Michael Stickland.;Sharla-Rae Olsen.;Donna Goodridge.
来源: Chest. 2020年158卷3期869-872页 3569. Prevalence of Anti-Neutrophil Cytoplasmic Antibodies and Associated Vasculitis in COPD Associated With Alpha-1 Antitrypsin Deficiency: An Ancillary Study to a Prospective Study on 180 French Patients.
作者: Samuel Deshayes.;Nicolas Martin Silva.;Kathy Khoy.;Delphine Mariotte.;Brigitte Le Mauff.;Jean-François Mornex.;Christophe Pison.;Antoine Cuvelier.;Malika Balduyck.;Marie-Christine Pujazon.;Michel Fournier.;Brahim Ait Ilalne.;Gabriel Thabut.;Hervé Mal.;Achille Aouba.
来源: Chest. 2020年158卷5期1919-1922页 3573. Building the Pyramids: A Perspective on Creating and Upscaling a Critical Care Workforce at a Public Hospital During the Coronavirus Disease 2019 Pandemic in New York City.
作者: Alok Bhatt.;Sunil Nair.;Radu Postelnicu.;Ashwin Basavaraj.;Amit Uppal.;Vikramjit Mukherjee.
来源: Chest. 2020年158卷3期884-886页 3577. Rurality, Stage-Stratified Use of Treatment Modalities, and Survival of Non-small Cell Lung Cancer.
作者: Meredith A Ray.;Nicholas R Faris.;Anna Derrick.;Matthew P Smeltzer.;Raymond U Osarogiagbon.
来源: Chest. 2020年158卷2期787-796页
To eliminate them, non-small cell lung cancer (NSCLC) care and outcome disparities need to be better understood.
3579. Typology of Published Randomized Controlled Trials Investigating Initial Ventilation Strategy in Critically Ill Patients With Acute Respiratory Failure: A Methodologic Review.
作者: Guillaume Dumas.;Sylvie Chevret.;Marine Le Corre.;Virginie Lemiale.;Samir Jaber.;Elie Azoulay.
来源: Chest. 2020年158卷3期986-998页
Randomized controlled trials (RCTs) in patients with hypoxemic acute respiratory failure (ARF) often failed to show survival benefits and resulted in varying clinical end points.
3580. Comparison of Diagnostic Sleep Studies in Hospitalized Neurorehabilitation Patients With Moderate to Severe Traumatic Brain Injury.
作者: Risa Nakase-Richardson.;Daniel J Schwartz.;Jessica M Ketchum.;Leah Drasher-Phillips.;Marie N Dahdah.;Kimberley R Monden.;Kathleen Bell.;Jeanne Hoffman.;John Whyte.;Jennifer Bogner.;Karel Calero.;Ulysses Magalang.
来源: Chest. 2020年158卷4期1689-1700页
OSA is prevalent during a time of critical neural repair after traumatic brain injury (TBI). The diagnostic utility of existing sleep studies is needed to inform clinical management during acute recovery from TBI.
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