241. The nomograph predicting the recurrence of Solid Pseudopapillary Neoplasm of the Pancreas: a study of the SEER database and a Chinese cohort.
作者: Qidong Pei.;Junzong Chen.;Gang Deng.;Dong Li.;Yajun Tang.;Jiaming Lai.;Di Tang.
来源: BMC Gastroenterol. 2025年25卷1期482页
Solid pseudopapillary neoplasm of the pancreas (SPN) represents a rare form of low-grade malignant pancreatic cystic neoplasm. This study seeks to construct a predictive nomograph model for SPN recurrence.
242. Research and experiments of a new premedication for improving mucosal visibility during esophagogastroduodenoscopy.
作者: Li-Na Qu.;Tao Jiang.;Yao-Ping Zhang.;Jin-Yong Hao.;Xiao-Jun Huang.
来源: BMC Gastroenterol. 2025年25卷1期450页
Mucus and bubbles are important factors that can reduce endoscope visibility. This may result in missed diagnoses of minor or early lesions. Therefore, dimethicone, such as drugs used before esophagogastroduodenoscopy (EGD), is called premedication. There is no uniform premedication worldwide. Moreover, the clinical effects of existing preoperative medications cannot meet the needs of endoscopists.
243. TyG-BMI as a superior predictor of MAFLD and pre-MAFLD in Chinese adults: a cross-sectional study.
作者: Xinru Huang.;Yanyun Hu.;Lining Dong.;Liying Zhu.;Jie Li.;Ji Hu.;Wei Shao.;Yongde Peng.;Fang Liu.
来源: BMC Gastroenterol. 2025年25卷1期495页
Metabolic-associated fatty liver disease (MAFLD), a highly prevalent global liver disorder, requires early diagnosis and treatment to delay progression, yet lacks simple diagnostic tools. We aimed to evaluate the validity of the triglyceride-glucose index (TyG) and its related indexes in predicting MAFLD and pre-MAFLD among Chinese individuals.
244. Association between blood lead levels and constipation in adults: insights from NHANES data (2005-2010).
作者: Yue-Juan Li.;Hui Dong.;Wen-Xing Chen.;Deng-Chao Wang.;Miao Yu.
来源: BMC Gastroenterol. 2025年25卷1期455页
Constipation is a common health issue affecting quality of life. While environmental factors like lead exposure may influence gastrointestinal function, the link between blood lead levels and constipation is underexplored. This study, based on NHANES data, investigates the association between blood lead levels and constipation prevalence in adults.
245. Evaluation of the risk level for celiac disease among adults in semi-rural and urban areas (Moungo and Wouri) in Cameroon: a questionnaire based study.
作者: William Djeukeu Asongni.;Julien Armel Assiéné Agamou.;Vanessa Boudjeka Guemkam.;Adelaide Demasse Mawamba.;Fabrice Fabien Dongho Dongmo.;Evariste Fongnzossie Fedoung.;Fernande Christine Nyangono Biyegue.;Inocent Gouado.
来源: BMC Gastroenterol. 2025年25卷1期459页
Data on the prevalence of celiac disease are scarce in Cameroon; however, it has been demonstrated that the effectiveness of self-reported questionnaires as a tool for identifying individuals at risk of celiac disease has been established. This study was therefore designed to assess the risk of celiac disease among adults in semi-rural and urban areas (Moungo and Wouri) using self-reported questionnaires.
246. Ultrasound-derived fat fraction: a novel approach for assessing Wilson's disease-related hepatic steatosis.
Ultrasound-derived fat fraction (UDFF) is a novel, non-invasive, rapid, and cost-effective technology that assesses liver fat content in various hepatic diseases. Its use in evaluating hepatic steatosis in Wilson’s disease (WD) remains largely unexplored. This study aimed to verify the clinical utility and measurement consistency of UDFF in assessing hepatic steatosis in WD, investigate the relationship between BMI and the severity of hepatic steatosis in WD patients, and determine if UDFF is an effective indicator for this condition.
247. U-shaped association of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with NAFLD: results from the NHANES database prospective cohort study.
作者: Yitian Dong.;Jiayuan Ye.;Hui Li.;Weiliang Kong.;Guoqing Qian.;Yilian Xie.
来源: BMC Gastroenterol. 2025年25卷1期477页
Stress hyperglycemia ratio (SHR), an index reflecting relative hyperglycemia under stress conditions, has been linked to adverse outcomes in various clinical settings. However, its prognostic significance in individuals with nonalcoholic fatty liver disease (NAFLD) remains poorly understood. This study aimed to examine the association between SHR and mortality risk in adults with NAFLD.
248. Clinical application of pre-rehabilitation concept on comfort colonoscopy in Chinese elderly patients: a randomised controlled trial.
作者: Lun Zhang.;Xiaoling Lv.;Qin Zhu.;Jianying Zhou.;Hanlei Huang.;Yiqian Huang.;Caijuan Si.
来源: BMC Gastroenterol. 2025年25卷1期457页
The concept of pre-rehabilitation has been clinically implemented across various surgical fields; however, studies investigating its application in colonoscopy remain limited. This study aimed to evaluate the effectiveness, safety, and patient satisfaction of the pre-rehabilitation concept in bowel preparation for comfort colonoscopy among elderly Chinese patients.
249. Effect of Allostatic Load on hepatic steatosis and fatty liver-associated liver fibrosis.
The Allostatic Load Index (ALI), as a comprehensive biomarker for assessing the body’s chronic stress response, has been widely used in quantitative studies of the physiological mechanisms of stress. In this study, we systematically investigated the relationship between ALI and hepatic steatosis and fibrosis through cross-sectional analysis.
250. Timing and other factors influencing shortterm outcomes of endoscopic transpapillary gallbladder drainage for acute cholecystitis: a retrospective study.
作者: Fumitaka Niiya.;Naoki Tamai.;Masataka Yamawaki.;Jun Noda.;Tetsushi Azami.;Yuichi Takano.;Fumiya Nishimoto.;Masatsugu Nagahama.
来源: BMC Gastroenterol. 2025年25卷1期469页
Endoscopic transpapillary gallbladder drainage (ETGBD) is used to manage acute cholecystitis (AC) in patients in whom surgery is contraindicated. However, ETGBD is considered challenging, has comparatively lower success rates, and is associated with severe adverse events (AEs). Only a few studies have examined the procedural and anatomical factors that affect the success of technical ETGBD. This study identified predictive factors for ETGBD in AC to improve success rates and minimize AEs.
251. The prognostic significance of desmoplastic reaction, tumor budding and tumor-infiltrating lymphocytes in esophageal squamous cell carcinomas.
作者: Ozlem Ceren Gunizi.;Busra Altunay.;Selin Didar Turgut.;Gulsum Ozlem Elpek.
来源: BMC Gastroenterol. 2025年25卷1期476页
Recent research has demonstrated the importance of the tumor microenvironment (TME) in the behavior of solid tumors. Numerous discoveries suggest that tumor progression in a variety of malignancies, including those of the gastrointestinal tract, may be predicted by pathological evaluation of the desmoplastic reaction (DR), tumor budding (TB) and tumor-infiltrating lymphocytes (TIL). While some studies have demonstrated the prognostic impact of TIL in patients with squamous cell carcinoma of the esophagus (ESCC), the data have not reached agreement. Furthermore, few studies have investigated the relationship of DR and TB with disease progression. The relationships between DR, TB and TIL in these tumors remain to be investigated. Therefore, this study was undertaken to explore the relationships between DR, TB and TIL and histopathological parameters related to tumor behavior and assess their prognostic role in predicting survival in patients with ESCC.
252. Global burden, trends, and risk factors of early-onset and late-onset colorectal cancer from 1990 to 2021, with projections to 2040: a population-based study.
作者: Hongfeng Pan.;Yongqin Tang.;Heyuan Zhu.;Yanwu Sun.;Pan Chi.;Ying Huang.
来源: BMC Gastroenterol. 2025年25卷1期486页
Early-onset colorectal cancer (EOCRC) and late-onset colorectal cancer (LOCRC) are significant public health concerns. There has been limited research comparing EOCRC and LOCRC, particularly regarding their global burden.
253. Comparative clinical outcomes of transcystic vs. transductal laparoscopic common bile duct exploration: a retrospective study.
作者: Xing-Guang Yang.;Ming Hu.;Wei-Feng Sun.;Tian-Liang Zhang.;Ji-Wu Yang.;Hui-Qiong Zhao.
来源: BMC Gastroenterol. 2025年25卷1期496页
This study aims to compare the therapeutic outcomes of transcystic laparoscopic common bile duct exploration (TC-LCBDE) and transductive laparoscopic common bile duct exploration (TD-LCBDE) for the treatment of common bile duct stones accompanied by gallstones.
254. Lipid metabolism disturbance and immune dysfunction in HBV-related acute-on-chronic liver failure: a retrospective cohort study.
This study aimed to elucidate the correlations among dyslipidemia, immune function, and clinical outcomes in patients with acute-on-chronic liver failure (ACLF), with particular emphasis on the clinical significance of lipid metabolism and cellular immune parameters in hepatitis B virus-associated ACLF (HBV-ACLF).
255. Diagnostic performances of adding transition and hepatobiliary phase to washout in gadoxetic acid-enhanced MRI for subcentimeter hepatocellular carcinoma.
作者: Li Yang.;Shengxiang Rao.;Kaipu Jin.;Lifang Wu.;Mengsu Zeng.;Ying Ding.
来源: BMC Gastroenterol. 2025年25卷1期483页
To compare the diagnostic performances of washout (WO) criteria confined to portal venous phase (PVP), extended to transition phase (TP) or hepatobiliary phase (HBP) for subcentimeter hepatocellular carcinoma (HCC) using gadoxetic acid-enhanced MRI.
256. Comparison of efficacy and safety between surgical and conservative treatments for hemorrhoids: a meta-analysis.
作者: Longfang Quan.;Xuelian Bai.;Fang Cheng.;Jin Chen.;Hangkun Ma.;Pengfei Wang.;Ling Yao.;Shaosheng Bei.;Xiaoqiang Jia.
来源: BMC Gastroenterol. 2025年25卷1期492页
Hemorrhoids, a common anorectal condition, can be managed through surgical or conservative treatments. The aim of this meta-analysis is to compare the efficacy and safety of surgical and conservative treatments for hemorrhoids.
257. Development and validation of a nomogram for predicting endoscopic healing in crohn's disease patients receiving infliximab treatment.
作者: Lixuan Li.;Ting Feng.;Xuanzhi Huang.;Xiaoman Zu.;Minhu Chen.;Yun Qiu.
来源: BMC Gastroenterol. 2025年25卷1期487页
The objective of this study was to identify prognostic clinicopathological factors in patients with Crohn's disease (CD) receiving infliximab (IFX) treatment and to develop a new nomogram for predicting outcomes in this population.
258. Impact of terminal ileal microbiota dysbiosis and tryptophan metabolism alterations on mental disorders in patients with Crohn's disease.
作者: Yin Lin.;Fang-Tao Wang.;Kai Xia.;Ren-Yuan Gao.;Yi-Ran Jiao.;Min Fang.;Chun-Qiu Chen.
来源: BMC Gastroenterol. 2025年25卷1期473页
Crohn's disease (CD) is a chronic non-specific inflammatory bowel disease with an increasing incidence worldwide. Patients with CD are facing elevated risk for mental disorders (MD) than healthy people, and chronic psychological stress is considered to trigger deterioration and relapse of CD. The microbiome-gut-brain axis (MGBA) is recognized as a crucial factor in unraveling this connection. Whereas, so far, few studies have revealed the relationship of the microbiota communities and tryptophan catabolites of the terminal ileum mucosa on gut-brain communication.
259. Diagnosis and treatment of hemothorax following local ablation in patients with primary liver cancer.
作者: Ningning Lu.;Chunwang Yuan.;Jianjun Li.;Bin Sun.;Qinsheng Shi.;Wenfeng Gao.;Liang Ma.;Yonghong Zhang.
来源: BMC Gastroenterol. 2025年25卷1期489页
To investigate the diagnosis and treatment methods for hemothorax resulting from local ablation in patients with primary liver cancer.
260. Association between dietary flavonoids intake and metabolic dysfunction-associated steatotic liver disease especially in non-smokers: a cross-sectional study in US adults.
作者: Linxiao Gao.;Haoyu Fang.;Yanhe Liu.;Wen Luo.;Jianping Gong.;Rong Ma.
来源: BMC Gastroenterol. 2025年25卷1期479页
The association between dietary flavonoids and fatty liver disease is still controversial. This study investigated the link between dietary flavonoids intake and metabolic-associated fatty liver disease (MAFLD) and metabolic dysfunction-associated steatotic liver disease (MASLD).
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