当前位置: 首页 >> 检索结果
2321. Indications, response, and side effects of biologic treatment in Behçet's disease: an 8-year study with follow-up.
作者: Saeedeh Shenavandeh.;Elham Aflaki.;Maryam Rasti Jahromi.;Afshin Borhani Haghighi.;Mohammad Ali Nazarinia.
来源: Reumatologia. 2024年62卷2期101-108页
The treatment of Behçet's disease has improved significantly with the introduction of biologic therapies. However, there is still a need for more information about their use. This study aimed to evaluate the indications, response, and side effects of biologic agents in patients with refractory or severe Behçet's disease in the south of Iran, their follow-up and reasons for changing the biologics.
2322. Bone turnover markers and muscle decay indicator in patients with proximal femur fracture - a case-control study.
作者: Marcin Łapiński.;Krystian Żarnovsky.;Katarzyna Czarzasta.;Bartosz Maciąg.;Grzegorz Maciąg.;Olga Adamska.;Artur Mamcarz.;Artur Stolarczyk.
来源: Reumatologia. 2024年62卷2期121-127页
Fracture of the proximal femur is common in elderly patients, in fact threatening their lives. Age-related sarcopenia may be involved in the imbalance resulting in the injury. Handy and readily accessible biochemical tests would be useful to assess the musculoskeletal system condition in daily practice. The aim of the study was to determine whether there is any relation between muscle decay and fracture of the proximal femur and to assess bone quality in elderly patients.
2323. Impact of acetabular roof's angle on precision of cup center of rotation reproduction and placement in total hip arthroplasty.
作者: Bartosz Maciąg.;Dawid Jegierski.;Bartłomiej Wilk.;Martyna Budzińska.;Grzegorz Maciąg.;Anna Kupczak.;Krystian Żarnovsky.;Marcin Łapiński.;Tomasz Kordyaczny.;Artur Stolarczyk.
来源: Reumatologia. 2024年62卷2期128-133页
Total hip arthroplasty (THA) is nowadays considered as the most effective treatment option for end-stage hip osteoarthritis (OA) and one of the most successful orthopedic procedures. Precise reproduction of the center of rotation (COR) is among the most important aspects of recreating native hip biomechanics after THA as it is strictly related to muscle tension and force distribution within the hip joint. Both vertical and horizontal shift in cup positioning and COR restoration are commonly observed radiological signs corresponding with lesser functional outcome. The aim of this study was to assess whether the superior border of the native acetabulum morphology has an impact on cup positioning and COR restoration in patients undergoing THA as treatment of primary OA of the hip.
2324. Ramosetron as an add-on therapy for refractory fibromyalgia: a randomized, double-blind, placebo-controlled trial.
作者: Dong-Jin Park.;Hyemin Jeong.;Sung-Eun Choi.;Ji-Hyoun Kang.;Jung-Kil Lee.;Shin-Seok Lee.
来源: Rheumatology (Oxford). 2024年63卷9期2372-2378页
This study aimed to assess the efficacy and safety of intravenous ramosetron for pain relief in patients with fibromyalgia (FM) unresponsive to conventional treatments.
2325. Anti-HMGCR myopathy: estimated five-fold higher incidence in Polynesian compared with European populations in Aotearoa/New Zealand.
作者: Ke Li Chow.;Paula Elizabeth Keating.;John Liston O'Donnell.
来源: Rheumatology (Oxford). 2025年64卷3期1362-1368页
In 2014 the incidence of anti-3-hydroxy-3-methylglutaryl-CoA-reductase (HMGCR) myopathy in New Zealand was ∼1.7 case/million persons/year. This study aimed to re-estimate the population incidence and assess ethnic variation in those aged >40 years old.
2326. Ex vivo cell-based assay for assessment of response to TNF inhibitors in patients with rheumatic diseases.
作者: Smadar Gertel.;May Rokach.;Ari Polachek.;David Levartovsky.;Adi Broyde.;Victoria Furer.;Tali Ofir Dovrat.;Jonathan Wollman.;Sara Pel.;Yoram Neufeld.;Ori Elkayam.
来源: Rheumatology (Oxford). 2025年64卷4期2233-2241页
There are five TNF inhibitors (TNFis), whose structure and signalling differ. An individual patient with a rheumatic disease may respond to one TNFi but not to another. In addition, 30-40% of patients with rheumatic diseases may respond inadequately to TNFis. The downstream signalling of the various TNFis may determine their clinical efficacy. Several reports have shown that the different TNFis exhibited differential effects on Th17 cells. We analysed the effects of the various TNFis on IL-17A expression in peripheral blood mononuclear cells (PBMCs) of patients with rheumatic diseases, in order to evaluate the possibility of predicting responses in an ex vivo setting.
2327. Extracorporeal membrane oxygenation for acute lung injury in idiopathic inflammatory myopathies-a potential lifesaving intervention.
作者: Boyang Zheng.;Ellen Eline.;Lillian Xu.;Kun Huang.;Greet Hermans.;Michael Perch.;Gordan Samoukovic.;Ellen De Langhe.;Maryam Dastmalchi.;Lisa Christopher-Stine.;Louise Pyndt Diederichsen.;Valérie Leclair.
来源: Rheumatology (Oxford). 2025年64卷4期2204-2208页
Idiopathic inflammatory myopathies (IIM) can present with acute IIM-related lung injury and respiratory failure, leading to a high mortality risk in intensive care units (ICU). Extracorporeal membrane oxygenation (ECMO) in acute respiratory distress syndrome can be lifesaving. We aimed to report a case series of IIM patients that received ECMO.
2329. Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomization.
作者: Sizheng Steven Zhao.;Sarah L Mackie.;Susanna C Larsson.;Stephen Burgess.;Shuai Yuan.
来源: Rheumatology (Oxford). 2025年64卷5期3012-3018页
PMR is an age-related inflammatory disease of unknown cause. We aimed to identify potentially modifiable risk factors and therapeutic targets for preventing or treating PMR.
2330. Executive summary: British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease.
作者: Elizabeth J Price.;Stuart Benjamin.;Michele Bombardieri.;Simon Bowman.;Sara Carty.;Coziana Ciurtin.;Bridget Crampton.;Annabel Dawson.;Benjamin A Fisher.;Ian Giles.;Peter Glennon.;Monica Gupta.;Katie L Hackett.;Genevieve Larkin.;Wan-Fai Ng.;Athimalaipet V Ramanan.;Saad Rassam.;Saaeha Rauz.;Guy Smith.;Nurhan Sutcliffe.;Anwar Tappuni.;Stephen B Walsh.
来源: Rheumatology (Oxford). 2025年64卷2期396-408页 2331. Epidemiology and diagnosis of gout in sub-saharan Africa: a scoping review.
作者: Ayouba Tinni Ismael.;Kabore Fulgence.;Bayala Yannick Laurent Tchenadoyo.;Yameogo Wendyam Nadège.;Zabsonre/Tiendrebeogo Wendlassida Stéphanie Joelle.;Ouedraogo Aboubakar.;Zongo Yamyelle Enselme.;Traore Awa.;Bonkoungou Marcellin.;Ouedraogo Dieu-Donné.
来源: BMC Rheumatol. 2024年8卷1期21页
The episodic nature of gout and diagnostic uncertainty in the absence of microcrystal evidence make it particularly difficult to estimate the frequency of gout. Our aim was to review the literature on the epidemiological and diagnostic aspects of gout in sub-Saharan Africa.
2333. ANCA-associated large and small vessel vasculitis with aorto-pulmonary-renal syndrome.
作者: Tajamul H Mir.;Parvaiz A Zargar.;Bushra Jabeen.;Muzamil Latief.;Alok Sharma.;Nisar A Wani.;Syed Mubashir Nissar.;Aabid Hussain.;Abid Kuchay.;Abdul Rasheed Ahangar.;Murtaza Rashid Pala.;M Omar Parvaiz.
来源: Lancet Rheumatol. 2024年6卷6期e409-e410页 2334. Identifying key health system components associated with improved outcomes to inform the re-configuration of services for adults with rare autoimmune rheumatic diseases: a mixed-methods study.
作者: Rosemary J Hollick.;Warren R G James.;Avril Nicoll.;Louise Locock.;Corri Black.;Neeraj Dhaun.;Allyson C Egan.;Nicholas Fluck.;Lynn Laidlaw.;Peter C Lanyon.;Mark A Little.;Raashid Ahmed Luqmani.;Laura Moir.;Maureen McBain.;Neil Basu.
来源: Lancet Rheumatol. 2024年6卷6期e361-e373页
Adults with rare autoimmune rheumatic diseases face unique challenges and struggles to navigate health-care systems designed to manage common conditions. Evidence to inform an optimal service framework for their care is scarce. Using systemic vasculitis as an exemplar, we aimed to identify and explain the key service components underpinning effective care for rare diseases.
2336. B cell depletion after treatment with rituximab predicts relapse of IgG4-related disease.
作者: Marco Lanzillotta.;Giuseppe Alvise Ramirez.;Raffaella Milani.;Lorenzo Dagna.;Emanuel Della-Torre.
来源: Rheumatology (Oxford). 2025年64卷4期2290-2294页
B cell depletion therapy with rituximab is effective in most patients with IgG4-related disease (IgG4-RD) but requires repeated cycles to prevent disease flares. We here aimed to assess B cells after rituximab to predict relapse of IgG4-RD and guide retreatment.
2337. Prospective assessment of glucocorticoid toxicity in rheumatology practice: a focus on the glucocorticoid toxicity index.
作者: Melda Bahap-Kara.;Emine Sariyildiz.;Hatice Yagmur Zengin.;Omer Karadag.;Aygin Bayraktar-Ekincioglu.
来源: Rheumatology (Oxford). 2025年64卷3期1010-1018页
The glucocorticoid toxicity index (GTI) is developed to measure glucocorticoid (GC)-related morbidity over time. This study aimed to assess GC-toxicity in patients at a rheumatology outpatient clinic by using the GTI and to identify the factors that interfere with the GTI.
2338. Treatment of psoriasis with different classes of biologics reduces the likelihood of peripheral and axial psoriatic arthritis development.
作者: Alberto Floris.;Cristina Mugheddu.;Leonardo Sichi.;Jasmine Anedda.;Alessia Frau.;Jessica Sorgia.;Laura Li Volsi.;Maria Teresa Paladino.;Mattia Congia.;Elisabetta Chessa.;Maria Maddalena Angioni.;Micaela Naitza.;Caterina Ferreli.;Matteo Piga.;Laura Atzori.;Alberto Cauli.
来源: Rheumatology (Oxford). 2025年64卷3期1131-1137页
To assess the potential role of biologic treatment for psoriasis (PsO) in reducing the likelihood of psoriatic arthritis (PsA) development, through a detailed analysis that considered the different historical phases in PsA management, the different biologic classes and the different patterns of articular involvement.
2339. Combination of scavenger receptor-A with anti-cyclic citrullinated peptide antibody for the diagnosis of rheumatoid arthritis.
作者: Chaonan Wei.;Ping Wang.;Jian Zhang.;Xiang Jiang.;Yang Xie.;Yingni Li.;Wei Zhang.;Yan Du.;Xi Zheng.;Xiangyu Fang.;Shuyan Liu.;Lulu Cao.;Ranran Yao.;Xu Jin.;Danxue Zhu.;Huaxiang Wu.;Yongfu Wang.;Zhanguo Li.;Fanlei Hu.
来源: Rheumatology (Oxford). 2025年64卷3期1513-1522页
The routine biomarkers for RA, including anti-CCP, RF, IgM, ESR and CRP, have limited sensitivity and specificity. Scavenger receptor-A (SR-A) is a novel RA biomarker identified recently by our group, especially for seronegative RA. Here, we performed a large-scale, multicentre study to further assess the diagnostic value of SR-A in combination with other biomarkers for RA.
2340. Polyarticular juvenile idiopathic arthritis has a distinct co-inhibitor receptor profile.
作者: Erdal Sag.;Zeynep Balik.;Selcan Demir.;Ummusen Akca Kaya.;Seher Sener.;Muserref Kasap Cuceoglu.;Erdal Atalay.;Sena Bocutcu.;Tayfun Vural.;Nur Kubra Tasdemir.;Busra Aydin.;Yelda Bilginer.;Bent Deleuran.;Seza Ozen.
来源: Rheumatology (Oxford). 2025年64卷3期1424-1430页
JIA is the most common rheumatic disease of childhood; the pathogenesis is associated with T-cell activation. T-cell activation can be counterbalanced by signals generated by inhibitory receptors (IRs) such as CTLA-4, PD-1, LAG-3 and TIM-3. Here, we identify the role of IRs in the pathogenesis of different JIA subtypes.
|