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201. Endobiliary radiofrequency ablation in recurrence and unresectable Perihilar cholangiocarcinoma.
作者: Apiwat Jareanrat.;Vasin Thanasukarn.;Tharatip Srisuk.;Vor Luvira.;Theerawee Tipwaratorn.;Anucha Ahooja.;Watcharin Loilome.;Piya Prajumwongs.;Attapol Titapun.
来源: BMC Gastroenterol. 2025年25卷1期501页
Palliative biliary stenting is the principal treatment for unresectable perihilar cholangiocarcinoma (pCCA) patients with jaundice. Endobiliary radiofrequency ablation (EBRFA) is a novel treatment used in combination with biliary stenting for CCA, aiming to prolong stent patency and patient survival. However, the evidence regarding its safety and efficacy in perihilar CCA remains limited. This study aims to investigate the safety of EBRFA and efficacy in terms of increasing stent patency and the patient's survival.
202. Portal vein thrombosis and Esophageal-Gastric variceal bleeding in cirrhosis: shared risk factors and causal relationship.
This study aims to investigate the shared risk factors and the causal relationship between esophageal varices bleeding (EGVB) and portal vein thrombosis (PVT) in cirrhotic patients.
203. Endoscopic characteristics and treatment modalities of gastrointestinal glomus tumors: a multicenter retrospective study.
作者: Yu-Qing Gong.;Hai-Xing Wang.;Lin Han.;Yi-Sen Huang.;Yi Ding.;Jin-Yan Zhang.;Zhong Xu.;Wei-Feng Huang.
来源: BMC Gastroenterol. 2025年25卷1期499页
Glomus tumors are rare mesenchymal neoplasms originating from glomus cells, most commonly occurring in the distal extremities, with rare occurrences in the gastrointestinal tract. This study aims to retrospectively analyze the endoscopic features and treatment modalities of gastrointestinal glomus tumor.
205. Dietary Patterns and Incident Chronic Constipation in Three Prospective Cohorts of Middle- and Older-Aged Adults.
作者: Yiqing Wang.;Braden Kuo.;Madeline Berschback.;Curtis Huttenhower.;Andrew T Chan.;Kyle Staller.
来源: Gastroenterology. 2025年
Current literature on diet-constipation associations is limited by small sample sizes and cross-sectional designs. We aimed to comprehensively examine the associations among 5 dietary patterns, their components, and incident constipation.
212. Comments on "Postoperative Endoscopic Outcomes in the MESOCOLIC Trial Investigating Mesenteric-Based Surgery for Crohn's Disease".
作者: Willem A Bemelman.;Anouck E G Haanappel.;Marjolijn Duijvestein.;Eline M L van der Does de Willebois.;Christianne J Buskens.
来源: Gastroenterology. 2025年 214. Peyer's Patch B Cells Sample Transglutaminase-Gluten Complexes and Drive Celiac Disease Autoimmunity.
作者: M Fleur du Pré.;Liv Kleppa.;Alisa E Dewan.;Maureen T Meling.;Lene S Høydahl.;Harrison A Besser.;Chaitan Khosla.;Ludvig M Sollid.
来源: Gastroenterology. 2025年
The production of autoantibodies against the enzyme transglutaminase 2 (TG2) in celiac disease likely results from TG2-specific B cells receiving help from gluten-specific CD4+ T cells in gut-associated lymphoid tissues (GALT) via the formation of transient enzyme-substrate complexes formed between TG2 and gluten. Where in the body enzymatically active TG2 encounters gluten peptides remains unknown.
215. The influence of subjective well-being on anxiety, depression and quality of life in patients with functional dyspepsia.
Subjective well-being (SWB) encompasses both subjective happiness and objective factors. Anxiety and depression are increasingly recognized as contributing causes of functional dyspepsia (FD), yet the role of SWB in FD patients has been largely overlooked. This study aims to investigate the influence of SWB on anxiety, depression, symptom severity, and quality of life (QoL) in individuals with FD.
216. Non-linear relationship between the hepatic steatosis index and glycemic progression: evidence from a large-scale retrospective cohort study in a Chinese population.
作者: Changchun Cao.;Yongyang Huo.;Yong Han.;Haofei Hu.;Fubing Zha.;Yulong Wang.
来源: BMC Gastroenterol. 2025年25卷1期484页
The hepatic steatosis index (HSI) is a validated tool for assessing hepatic steatosis. While previous investigations have explored the link between HSI and prediabetes and diabetes, the connection between HSI and glycemic progression is still being explored. This research seeks to clarify the association between HSI and glycemic progression risk among a Chinese demographic.
217. Prognostic role of preoperative inflammatory markers in postoperative lung metastasis of colorectal cancer: a retrospective study.
This study aims to investigate the predictive significance of inflammatory markers for postoperative lung metastasis in colorectal cancer (CRC) patients. The focus is on exploring the relationship between traditional inflammatory markers, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and newly introduced indices like C-reactive protein (CRP)-albumin-lymphocyte (CALLY), and their association with CRC progression and lung metastasis.
218. Timing of endoscopy in patients with acute variceal bleeding in cirrhosis: an updated systematic review and meta-analysis.
Endoscopy is a critical tool in the management of acute variceal bleeding (AVB). However, the optimal timing for its implementation remains controversial, with varying recommendations across different clinical guidelines. This study aims to evaluating the impact of endoscopy timing on patient outcomes.
219. The experiences of fertility concerns in women with inflammatory bowel disease of childbearing age: a descriptive qualitative study.
作者: Lewei Tu.;Qiaoyu Wu.;Mengxiao Jiang.;Meihao Wei.;Ying Wang.;Ying Xiao.
来源: BMC Gastroenterol. 2025年25卷1期481页
Since the onset of inflammatory bowel disease (IBD) symptoms among females is usually in the reproductive years, issues regarding pregnancy and childbearing are prevalent. Relatively few studies have focused on the fertility concerns of women with IBD.
220. Inflammatory and nutritional markers predict response and prognosis of patients with locally advanced gastric cancer receiving neoadjuvant immunochemotherapy.
作者: Yiwen Sun.;Mengjie Liang.;Xingzhou Wang.;Wenting Dong.;ZhenShui Wu.;Feng Sun.;Xiaofeng Lu.;Feng Wang.;Song Liu.;Meng Wang.;Shichao Ai.;Xiaofei Shen.;Wenxian Guan.
来源: BMC Gastroenterol. 2025年25卷1期478页
Metabolism plays an important role in the occurrence and development of gastric cancer, including in neoadjuvant immunochemotherapy. However, whether nutrition-related indicators can predict the efficacy of neoadjuvant immunochemotherapy and the prognosis of gastric cancer patients has not been addressed. This study systematically screens various nutritional indicators to explore their efficacy in predicting responses to neoadjuvant immunochemotherapy and patients' prognosis in locally advanced gastric cancer (LAGC).
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