当前位置: 首页 >> 检索结果
2082. Long-term efficacy of MAS825, a bispecific anti-IL1β and IL-18 monoclonal antibody, in two patients with systemic JIA and recurrent episodes of macrophage activation syndrome.
作者: Roberta Caorsi.;Arinna Bertoni.;Caterina Matucci-Cerinic.;Valentina Natoli.;Serena Palmeri.;Silvia Rosina.;Federica Penco.;Clara Malattia.;Alessandro Consolaro.;Stefania Viola.;Riccardo Papa.;Anna Corcione.;Stefano Volpi.;Angelo Ravelli.;Marco Gattorno.
来源: Rheumatology (Oxford). 2025年64卷3期1528-1533页
Systemic JIA (sJIA), a multifaceted autoinflammatory disorder, can be complicated by life-threatening conditions such as macrophage activation syndrome (MAS) and interstitial lung disease. The management of these conditions presents a therapeutic challenge, underscoring the need for innovative treatment approaches.
2084. Large vessel vasculitis is a risk factor for relapse only in giant cell arteritis patients without polymyalgia rheumatica.
作者: Lien Moreel.;Albrecht Betrains.;Lennert Boeckxstaens.;Geert Molenberghs.;Koen Van Laere.;Ellen De Langhe.;Steven Vanderschueren.;Daniel Blockmans.
来源: Rheumatology (Oxford). 2025年64卷4期2068-2076页
To evaluate differences in presentation and outcome of GCA patients with and without large vessel vasculitis (LVV) and according to the extent and severity of LVV.
2085. Rheumatoid arthritis and the risk of ischaemic stroke after diagnosis of atrial fibrillation: a Norwegian nationwide register study.
作者: Anne M Kerola.;Eirik Ikdahl.;Ingrid Engebretsen.;Christoffer Bugge.;Anne Grete Semb.
来源: Rheumatology (Oxford). 2024年63卷11期2997-3005页
RA patients have an increased risk for cardiovascular diseases, including atrial fibrillation (AF), but the impact of RA on ischaemic stroke risk in the context of AF remains unknown. We explored whether the risk of ischaemic stroke after diagnosis of AF is further increased among patients with RA compared with non-RA patients.
2088. Glucocorticoid sparing effect of Janus kinase inhibitors compared to biologic disease modifying anti-rheumatic drugs in rheumatoid arthritis, a single-centre retrospective analysis.
作者: Giovanni Adami.;Riccardo Bixio.;Giulia Virelli.;Isotta Galvagni.;Francesca Mastropaolo.;Andrea Morciano.;Francesca Ruzzon.;Valeria Messina.;Elena Fracassi.;Davide Gatti.;Ombretta Viapiana.;Antonio Carletto.;Maurizio Rossini.
来源: Rheumatology (Oxford). 2025年64卷4期1698-1704页
Glucocorticoid sparing in rheumatoid arthritis (RA) treatment is crucial to minimizing adverse effects associated with long-term use. Janus kinase inhibitors (JAKi) could potentially offer a more potent glucocorticoid-sparing effect than biologic DMARDs (bDMARDs).
2089. Incidence of chronic recurrent multifocal osteomyelitis in children and adolescents in the UK and Republic of Ireland.
作者: Daphne Theresa Chia.;Andoni Paul Toms.;Anish Sanghrajka.;Athimalaipet V Ramanan.;Orla G Killeen.;Cristina Ilea.;Kamran Mahmood.;Sandrine Compeyrot-Lacassagne.;Kathryn Bailey.;Neil Martin.;Kate Armon.;Chenqu Suo.
来源: Rheumatology (Oxford). 2025年64卷4期2162-2170页
Chronic recurrent multifocal osteomyelitis (CRMO), also known as chronic non-bacterial osteomyelitis (CNO), is a rare autoinflammatory condition affecting the bones in children and teenagers. The actual incidence of CRMO remains uncertain. The objective of this study was to identify the incidence of CRMO in children and young people under the age of 16 years in the United Kingdom (UK) and Republic of Ireland (ROI). We also aimed to delineate the demographics, clinical presentation, investigations, initial management and healthcare needs for children and adolescents with CRMO.
2090. Identifying enthesitis in the sacroiliac joints in patients with axial spondyloarthritis by readers of varying experience: impact of the learning progress.
作者: Dong Liu.;Jiaoshi Zhao.;Churong Lin.;Budian Liu.;Jinwei Li.;Yuxuan Zhang.;Ou Jin.;Jieruo Gu.
来源: BMC Rheumatol. 2024年8卷1期36页
This study aimed to investigate the accuracy of identifying enthesitis along with other inflammatory lesions and structural lesions on the MRI of the sacroiliac joints (SIJ) by readers of varying experience and how training sessions and workshops could help improve the accuracy.
2092. Pregnancy outcome predictors in systemic lupus erythematosus: a systematic review and meta-analysis.
作者: Merlijn Wind.;Juan J Fierro.;Kitty W M Bloemenkamp.;Karina de Leeuw.;A Titia Lely.;Maarten Limper.;Marieke Sueters.;Y K Onno Teng.;Isabel J Walter.;Judith Kooiman.
来源: Lancet Rheumatol. 2024年6卷10期e667-e683页
To enhance patient-tailored preconception risk assessment for women with systemic lupus erythematosus (SLE), knowledge on risk factors associated with adverse pregnancy outcomes is required. Therefore, we did a systematic review and meta-analysis to identify and provide unambiguous effect sizes of preconception predictors of pregnancy outcomes in women with SLE.
2094. Comment on: Hydroxychloroquine levels in pregnancy and materno-fetal outcomes in Systemic Lupus Erythematosus patients: Reply.
作者: Gelsomina Alle.;Gaëlle Guettrot-Imbert.;Anna Molto.;Nathalie Costedoat-Chalumeau.; .
来源: Rheumatology (Oxford). 2025年64卷5期3203-3204页 2095. Hepatitis B reactivation in PsA patients: an SLR and meta-analysis for IL-17, IL-23 and JAK inhibitors.
作者: Theodoros Androutsakos.;Konstantinos Dimitriadis.;Maria-Loukia Koutsompina.;Konstantinos D Vassilakis.;Avraam Pouliakis.;George E Fragoulis.
来源: Rheumatology (Oxford). 2025年64卷3期935-942页
HBV reactivation (HBVr) constitutes a side effect of the treatment of autoimmune rheumatic diseases. Even though HBVr risk of conventional synthetic DMARDs (csDMARDs) and anti-tumor necrosis factor (anti-TNF) agents has long been established, the risk of targeted synthetic (ts)DMARDs and anti-interleukin (anti-IL) agents remains largely unknown.
2096. Multimodal imaging of structural damage and inflammation in psoriatic arthritis: a comparison of DMARD-naive and DMARD-failure patients.
作者: Nağme Ö Renkli.;Nienke J Kleinrensink.;Julia Spierings.;Simon Mastbergen.;Harald E Vonkeman.;Shasti C Mooij.;Lydia G Schipper.;Amin Herman.;Iris Ten Katen.;Frank J Nap.;Marjolein E Hol.;Pim A de Jong.;Mylène P Jansen.;Wouter Foppen.; .
来源: Rheumatology (Oxford). 2025年64卷4期1760-1769页
To compare inflammatory and structural differences in active PsA between DMARD-naive and DMARD-failure patients using diverse imaging approaches for future analyses. Additionally, to explore the influence of patient characteristics (clinical and demographic variables) on imaging findings.
2098. Treatment of giant cell arteritis with ultra-short glucocorticoids and tocilizumab: results from the extension of the TOPAZIO study.
作者: Francesco Muratore.;Chiara Marvisi.;Giulia Cassone.;Caterina Ricordi.;Luigi Boiardi.;Pamela Mancuso.;Giulia Besutti.;Lucia Spaggiari.;Massimiliano Casali.;Stefania Croci.;Rexhep Durmo.;Annibale Versari.;Gabriella Di Tommaso.;Mariagrazia Catanoso.;Paolo Giorgi Rossi.;Carlo Salvarani.
来源: Rheumatology (Oxford). 2025年64卷5期3057-3062页
To assess the maintenance of efficacy of one year of tocilizumab (TCZ) monotherapy after its discontinuation in large vessel-GCA (LV-GCA).
2100. Factors associated with long-term opioid use among patients with axial spondyloarthritis or psoriatic arthritis who initiate opioids.
作者: Yun-Ting Huang.;David A Jenkins.;Belay Birlie Yimer.;Meghna Jani.
来源: Rheumatology (Oxford). 2025年64卷4期1844-1852页
Up to one in five patients with axial spondyloarthritis (AxSpA) or psoriatic arthritis (PsA) newly initiated on opioids transition to long-term use within the first year. This study aimed to investigate individual factors associated with long-term opioid use among opioid new users with AxSpA/PsA.
|