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1. Investigating the Risk of Arrhythmogenesis Associated With Fentanyl Abuse Using Human and Mouse Cardiomyocytes.
作者: Gema Mondéjar-Parreño.;Shane Rui Zhao.;Xu Cao.;Yu Liu.;Johnson Y Yang.;James W S Jahng.;Jeremy Leitz.;David Wu.;Nazish Sayed.;José Jalife.;Joseph C Wu.
来源: Circulation. 2025年152卷8期563-566页 2. Clinical Practice of Surgical Treatment for Left-Sided Infective Endocarditis: Nationwide Data from the NIDUS Registry.
作者: Peter Laursen Graversen.;Lauge Østergaard.;Katra Hadji-Turdeghal.;Jacob Eifer Møller.;Niels Eske Bruun.;Jonas Agerlund Povlsen.;Claus Moser.;Morten Smerup.;Peter Søgaard.;Hanne Sortsøe Jensen.;Ivy Susanne Modrau.;Andreas Dalsgaard Jensen.;Jeppe Kofoed Petersen.;Eva Havers-Borgersen.;Anna Stahl.;Jannik Helweg-Larsen.;Daniel Faurholt-Jepsen.;Henning Bundgaard.;Kasper Iversen.;Lars Køber.;Emil Loldrup Fosbøl.
来源: Circulation. 2025年
Surgery is an essential treatment for selected patients with infective endocarditis (IE). Despite indications for surgery, not all patients undergo surgery. Most previous IE cohorts have examined a selected group of patients from primary tertiary centers. Thus, the aims of this study were to describe the use of surgery by indication and to assess mortality in a nationwide cohort of patients with left-sided IE.
4. Preintervention Intake of Whole Grains Versus Refined Grains, and the Gut Microbiome, Discriminate the Antihypertensive Effect of Prebiotic Fiber.
作者: Matthew Snelson.;Dakota Rhys-Jones.;Hamdi A Jama.;Darren J Creek.;Charles R Mackay.;Jane Muir.;Francine Z Marques.
来源: Circ Genom Precis Med. 2025年e005019页 5. Prognostic Role of Myocarditis-Like Episodes and Their Treatment in Patients With Pathogenic Desmoplakin Variants.
作者: Alessio Gasperetti.;Steven A Muller.;Giovanni Peretto.;Babken Asatryan.;Alexandros Protonotarios.;Mikael Laredo.;Pierre-Yves Tarlet.;Petros Syrris.;Richard T Carrick.;Brittney Murray.;Crystal Tichnell.;Paul Scheel.;Marta Gigli.;Sing-Chien Yap.;Kalliopi Pilichou.;Cristina Basso.;Kristen Medo.;Max Jason.;Valentina A Rossi.;Ardan M Saguner.;Firat Duru.;Dominic Abrams.;Julia Cadrin-Tourigny.;Mattia Targetti.;Maurizio Pieroni.;Maddalena Graziosi.;Elena Biagini.;Philippe Charron.;Moniek Cox.;Michela Casella.;Claudio Tondo.;James S Ware.;Sanjay K Prasad.;Leonardo Calò.;Eric Smith.;Jodie Ingles.;Harikrishna Tandri.;Flavie Ader.;Stacey Peters.;Dominica Zentner.;Jeremy Russo.;Silvia Ravaro.;Lia Crotti.;Svenn Dittmann.;Eric Shulze-Bahr.;Eric D Carruth.;Vikki A Krysov.;Victoria N Parikh.;Giulio Conte.;Arthur Wilde.;J Peter van Tintelen.;Anneline S J M Te Riele.;Gianfranco Sinagra.;Luisa Mestroni.;Matthew Taylor.;Marco Merlo.;Luigi Adamo.;Hugh Calkins.;Barbara Bauce.;Elena Arbelo.;Perry M Elliott.;Estelle Gandjbakhch.;Neal Lakdawala.;Adam Helms.;Cynthia A James.;Nisha A Gilotra.
来源: Circulation. 2025年
Inflammatory, myocarditis-like episodes precede and are associated with higher risk of sustained ventricular arrhythmias and heart failure in patients with pathogenic or likely pathogenic desmoplakin (DSP) variants. Whether the recurrence and treatment of myocarditis-like episodes influence the outcomes in this population is unknown. This study aimed to assess the prognostic impact of the recurrence and treatment of myocarditis-like episodes in patients with pathogenic or likely pathogenic DSP variants.
7. Efficacy and Safety of SGLT2 Inhibitors in Heart Failure: Observational Evidence in Geriatric Patients AGING-HF.
作者: Abdelhakim Hacil.;Yara Antakly Hanon.;Audrey Lacour.;Jean-Philippe David.;Tesnim Khalifa.;Matthieu Piccoli.;Aude Clemencin.;Patrick Assayag.;Jean-Sebastien Vidal.;Olivier Hanon.
来源: Circ Heart Fail. 2025年e012794页
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have shown beneficial effects in heart failure (HF) management, but data on their use in geriatric populations with high comorbidity remain limited. This observational study aimed to assess the real-world efficacy and safety of SGLT2i in elderly patients with HF.
8. Sarcopenia Assessment Using Fully Automated Deep Learning Predicts Cardiac Allograft Survival in Heart Transplant Recipients.
作者: Frederick M Lang.;Jianfei Liu.;Kevin J Clerkin.;Elissa A Driggin.;Andrew J Einstein.;Gabriel T Sayer.;Koji Takeda.;Nir Uriel.;Ronald M Summers.;Veli K Topkara.
来源: Circ Heart Fail. 2025年e012805页
Sarcopenia is associated with adverse outcomes in patients with end-stage heart failure. Muscle mass can be quantified via manual segmentation of computed tomography images, but this approach is time-consuming and subject to interobserver variability. We sought to determine whether fully automated assessment of radiographic sarcopenia by deep learning would predict heart transplantation outcomes.
9. Natriuretic Peptide Cut Points for Heart Failure Classification in Individuals With and Without Obesity.
作者: Mandana Chitsazan.;Juhi K Parekh.;Leah B Kosyakovsky.;Sophie M Nemeth.;Emily S Lau.;James L Januzzi.;Thomas J Wang.;Daniel Levy.;Chiadi E Ndumele.;Elizabeth Selvin.;Christie Ballantyne.;Bruce M Psaty.;John S Gottdiener.;Jorge R Kizer.;Christopher R deFilippi.;Norrina B Allen.;Rudolf A de Boer.;Sanjiv J Shah.;Jennifer E Ho.
来源: Circ Heart Fail. 2025年e013112页
The 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America guidelines introduced elevated natriuretic peptide (NP) levels as a criterion for defining stage B heart failure (HF), or pre-HF, to identify individuals at greatest risk for future HF. Given the known NP deficiency in obesity, we aimed to assess whether a single NP cut point would disproportionately up-classify individuals with versus without obesity to stage B HF.
10. Changes in Heart Transplant Listings by Insurance and Race During the COVID Public Health Emergency.
作者: Daniel K Fox.;R J Waken.;Fengxian Wang.;Khavya Avula.;David S Raymer.;Justin Vader.;Joel Schilling.;Karen E Joynt Maddox.
来源: Circ Heart Fail. 2025年e012306页
Socioeconomic inequities in access to heart transplantation, including those based on insurance coverage and race or ethnicity, are well documented. During the COVID pandemic, the federal government declared a Public Health Emergency (PHE), which prevented states from disenrolling people from Medicaid. We sought to determine whether this policy was associated with changes in the insurance or racial composition of the heart transplant waiting list.
11. National Patterns of Remote Patient Monitoring Service Availability at US Hospitals.
作者: Aline F Pedroso.;Zhenqiu Lin.;Joseph S Ross.;Rohan Khera.
来源: Circ Cardiovasc Qual Outcomes. 2025年e012034页
Digital remote patient monitoring (RPM), such as home-based blood pressure, heart rate, or weight monitoring, enables longitudinal care outside traditional health care settings, especially in the vulnerable period after hospitalizations, with broad coverage of the service by payers. We sought to evaluate patterns of RPM service availability at US hospitals and the characteristics of hospitals and the counties they serve that are associated with the availability of these services.
12. Transjugular Approach for Evoque Transcatheter Tricuspid Valve Replacement in Patients With Challenging Anatomy.
作者: Jonathan X Fang.;Pedro A Villablanca.;Tiberio M Frisoli.;Gennaro Giustino.;Leo Kar Lok Lai.;James C Lee.;Pedro Engel Gonzalez.;Bryan Zweig.;Hussayn Alrayes.;Georgi K Fram.;Felix Nguyen.;Ahmad Jabri.;Tyler Andrews.;Omar Abdelhai.;Gautam Rangavajla.;William W O'Neill.;Brian P O'Neill.
来源: Circ Cardiovasc Interv. 2025年e015276页
The Evoque system is the first commercially available transcatheter tricuspid valve replacement (TTVR) system in the United States. However, challenging anatomy in real-world patients could preclude successful transfemoral Evoque TTVR. We aim to investigate the feasibility of the transjugular Evoque TTVR in anatomy unsuitable for a transfemoral approach.
13. Safety and Effectiveness of Intracoronary Imaging-Guided PCI in Contemporary Practice: Insights From BMC2.
作者: Thomas Basala.;Milan Seth.;Ryan D Madder.;Brett Wanamaker.;Brittany Fuller.;Evan Shlofmitz.;Edouard Daher.;Michael Tucciarone.;Chadi Alraies.;Amir Kaki.;Sunil V Rao.;Hitinder S Gurm.;Devraj Sukul.
来源: Circ Cardiovasc Interv. 2025年e014886页
Studies suggest percutaneous coronary intervention (PCI) guided by intracoronary imaging (ICI) results in larger balloon/stent diameters and longer stents. Whether this occurs in real-world PCI is poorly understood.
14. Response by Demir et al to Letter Regarding Article, "Pressure Derived Indices in the Left Main Coronary Artery: Insights From Comprehensive In Vivo Hemodynamic Studies of Diseased and Unobstructed Vessels".15. American Heart Association National Integrated ASCVD Initiative: An Implementation Initiative to Improve Lipid Management Among Patients With ASCVD.
作者: Chiadi E Ndumele.;Ankeet S Bhatt.;Lynne T Braun.;Steven Chen.;Seth S Martin.;Michael T Mullen.;Nishant P Shah.;Stephen L Sigal.;Tracy Yu-Ping Wang.;Rebecca Alicki.;Chandler Beon.;Haoyun Hong.;Sara O'Kane.;Katherine J Overton.;Kathie Thomas.;Howard Haft.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷8期e011627页 16. Cost-Effectiveness of Hypertension Treatment According to 2017 American College of Cardiology and American Heart Association Guidelines.
作者: Joanne M Penko.;Brandon K Bellows.;Susan Hennessy.;Dhruv S Kazi.;Ross Boylan.;Yiyi Zhang.;Pamela G Coxson.;Lee Goldman.;Kirsten Bibbins-Domingo.;Andrew E Moran.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷8期e011872页
Compared with the 2003 Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) guideline, the 2017 American College of Cardiology and American Heart Association guideline (ACC/AHA 2017) expanded hypertension diagnostic criteria to blood pressure (BP) ≥130/80 mm Hg and intensified treatment goals to <130/80 mm Hg. The cost-effectiveness of ACC/AHA 2017 guideline treatment has not been quantified.
19. Letter by Kornelius Regarding Article, "Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial".20. Reformulation of the Necroptosis Pathway in Reperfused Myocardial Infarction.
作者: Dongze Qin.;Radheshyam Modanwal.;Madeeha Ghazi.;J Jose Corbalan.;Xiaotong F Jia.;Joshua L Axelrod.;Roneldine Mesidor.;Hee Jae Jang.;Claudio Humeres.;Anis Hanna.;Fahimeh Varzideh.;Michelle D Tallquist.;Gaetano Santulli.;Qinghang Liu.;Lorrie A Kirshenbaum.;Hongmin Ni.;Timothy J Kamp.;Rebekah L Gundry.;Siddharth Balachandran.;Alexei Degterev.;John W Calvert.;Richard N Kitsis.
来源: Circulation. 2025年152卷7期486-488页 |