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共有 977 条符合本次的查询结果, 用时 8.5364391 秒

1. BP-lowering drugs reduced major CV events to a similar extent in patients with or without isolated diastolic hypertension.

作者: Chirag Bavishi.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text].

2. Multisite External Validation of a Clinical Screening Tool for Interpersonal Firearm Violence Risk.

作者: Jason E Goldstick.;Patrick M Carter.;M Kit Delgado.;Lauren Whiteside.;Rebecca M Cunningham.
来源: Ann Intern Med. 2026年
Screening tools for interpersonal firearm violence (FV) are needed to facilitate prevention.

3. In MINOCA, stratified treatment guided by MINOCA cause vs. standard care improved angina status at 1 y.

作者: Giulio Francesco Romiti.;Bernadette Corica.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text].

4. In sepsis, a tailored precision immunotherapy strategy improved organ function at 9 d.

作者: Sias J Scherger.;Andre C Kalil.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Infectious Disease:[Formula: see text] Critical Care:[Formula: see text] Pulmonology:[Formula: see text].

5. In patients with painful diabetic neuropathy, pregabalin does not differ from duloxetine for pain.

作者: Margretta Diemer.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Endocrinology:[Formula: see text].

6. In the ED, the Wells score plus age-adjusted D-dimer score ruled out DVT with a failure rate ≤0.8% at 3 mo.

作者: Conor Bell.;Jeffrey I Weitz.; .
来源: Ann Intern Med. 2026年
Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Hematology:[Formula: see text].

7. In patients with chronic lung disease, 4 existing PE diagnostic strategies were assessed.

作者: Arnav Agarwal.;Natasha Goumeniouk.;Eddy Lang.; .
来源: Ann Intern Med. 2026年
Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Hematology:[Formula: see text].

8. In adults with ADHD, atomoxetine, methylphenidate, and CBT reduce symptom severity and the drugs are less tolerable vs. control at 12 wk.

作者: Gary M Onady.; .
来源: Ann Intern Med. 2026年
Mental Health:[Formula: see text] GIM/FP/GP:[Formula: see text].

9. In newly diagnosed polymyalgia rheumatica, weekly methotrexate improved glucocorticoid-free remission rates at 1 y.

作者: Ami Schattner.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Rheumatology:[Formula: see text].

10. After ischemic stroke in patients receiving aspirin, switching to another antithrombotic regimen does not reduce recurrence.

作者: Hajeera Shaik.;Dinesh Jillella.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text] Hematology:[Formula: see text].

11. In adults with T1D and overweight or obesity, adding GLP-1 RAs to insulin reduces weight, HbA1c levels, and insulin dose.

作者: David J McDonnell.;Sean F Dinneen.; .
来源: Ann Intern Med. 2026年
GIM/FP/GP:[Formula: see text] Endocrinology:[Formula: see text].

12. Functional Status of Adults at Risk of Medicaid Disenrollment Under National Work Requirements.

作者: Darshali A Vyas.;Stephen A Mein.;Archana P Tale.;Rishi K Wadhera.
来源: Ann Intern Med. 2026年
The One Big Beautiful Bill Act (H.R.1) implemented Medicaid work requirements for beneficiaries in states participating in the Affordable Care Act, but congressional policymakers are considering extending work requirements nationally to all Medicaid enrollees. However, little is known about Medicaid-enrolled adults at risk of disenrollment.

13. The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial.

作者: Gilmar Reis.;Eduardo Augusto Dos Santos Moreira Silva.;Daniela Carla Medeiros Silva.;Lehana Thabane.;Thiago Santiago Ferreira.;Luiza Lanna França Reis.;Ana Paula Figueiredo Guimaraes Almeida.;Marcela Menezes Amaral.;Leonardo Cançado Monteiro Savassi.;Vitoria Helena de Souza Campos.;Maria Izabel Campos Simplicio.;Luciene Barra Ribeiro.;Thalyne de Souza Medeiros.;Thais Campos Siqueira.;Taynara Silva Vieira.;Nayara Drumond Rausse.;Tereza Cristina Garofolo.;Eliane Carreiro Fagundes Silva.;Ofir Harari.;Gennaro D'Urso.;Jamie I Forrest.;Jay Park.;Jean B Nachega.;Christopher Lindsell.;Jeffrey S Glenn.;Kristian Thorlund.;Mark Dybul.;Edward J Mills.; .
来源: Ann Intern Med. 2026年
Postacute sequelae of SARS-CoV-2, or long COVID, presents a major therapeutic challenge, with fatigue being a prevalent and debilitating symptom.

14. Prevention of Recurrent Nephrolithiasis in Adults and Children : A Systematic Review.

作者: Gary N Asher.;Davis P Viprakasit.;Shannon E Aymes.;Jay B Lusk.;Sherry Ross.;Claire Baker.;Caroline Rains.;Sarah T Wright.;Leila C Kahwati.
来源: Ann Intern Med. 2026年
Recurrent kidney stones are unpleasant and may lead to kidney damage, sepsis, or invasive procedures.

15. Timing of Pegfilgrastim Administration and Pegfilgrastim-Induced Bone Pain : A Prospective, Randomized, Phase 3 Trial.

作者: Peiyong Li.;Yitian Chen.;Yingyi Lin.;Xiaoqi Zhang.;Minyi Cheng.;Teng Zhu.;Hong-Fei Gao.;Liulu Zhang.;Jieqing Li.;Na Huang.;Yilin Chen.;Minting Liang.;Yuanqi Zhang.;Shengchao Huang.;Junqiu Zheng.;Cangui Wu.;Ciqiu Yang.;Kun Wang.
来源: Ann Intern Med. 2026年
Pegfilgrastim-induced bone pain (PIBP) is common and lacks effective treatment.

16. Firearm Acquisition and New Exposure to Household Firearms After the Initial Pandemic Purchasing Surge: Results From the 2024 National Firearms Survey.

作者: Matthew Miller.;Samuel Fischer.;Deborah Azrael.
来源: Ann Intern Med. 2026年
Firearm acquisitions in the United States surged after the onset of the pandemic. The increase, sustained through at least early 2021, resulted from a modest increase in the proportion of long-standing gun owners who purchased firearms (most were White and men) and an unprecedented increase in the proportion of adults who became new gun owners (half were women; half were Hispanic and/or people of color). Little is known about firearm acquisitions beyond 2021.

17. New GRADE Evidence-to-Decision Framework for Pairwise and Multiple Comparisons (GRADE Guidance 45).

作者: Jessica Beltran.;Itziar Etxeandia-Ikobaltzeta.;Thomas Piggott.;Elie A Akl.;Reem A Mustafa.;Glen Hazlewood.;Carlos Canelo-Aybar.;Nancy Santesso.;Romina Brignardello-Petersen.;Alexander G Mathioudakis.;Alonso Carrasco-Labra.;Francesco Nonino.;Hans de Beer.;Martin Mayer.;Tatyana Shamliyan.;Wojtek Wiercioch.;Bart Dietl.;Gordon Guyatt.;Holger J Schünemann.;Pablo Alonso-Coello.
来源: Ann Intern Med. 2026年
Evidence-based decision making in health often requires comparison of multiple options for a given condition. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) evidence-to-decision (EtD) framework provides a structured approach for moving from evidence to decisions but was originally designed for pairwise comparisons. Hence, there is a need to accommodate decision making based on multiple comparisons, especially with the increasing use of systematic reviews and network meta-analyses in guideline development. Furthermore, since the original EtD framework was developed, further relevant GRADE guidance has been developed. The aim of this work was to develop a new EtD framework to accommodate multiple comparisons and reflect current GRADE guidance. The new EtD framework was revised and developed through iterative discussion, feedback, and refinement by the GRADE EtD Project Group and the GRADE Working Group. Experiences and examples from guideline developers, methodological experts, and other stakeholders informed improvements in its structure and usability for multiple comparisons and were subsequently approved by the GRADE Working Group. This article describes the new EtD framework, which now includes 2 corresponding parts for reviews of pairwise and multiple comparisons. The authors describe application to a review with multiple comparisons for the different parts of the EtD framework: the question definition, which now includes the presentation of values of health outcomes and decision thresholds; the assessment section, where the new "net effect" criterion has been included; and the conclusion section, which includes an adaptation for multiple comparisons. The article provides examples and suggestions for presentation of findings. The framework does have limitations, in that its usability has not been tested across a broad spectrum of guideline development contexts.

18. Determining the Conclusiveness of Systematic Review Evidence : A Scoping Review of Methodological Approaches.

作者: Jong-Wook Ban.;Troels Madsen.;Karen A Robinson.;Hans Lund.
来源: Ann Intern Med. 2026年
Systematic reviews can inform research, funding, and guideline decisions. However, it can be challenging to know whether a systematic review has answered a research question conclusively, and it is unclear which methods exist for such assessments.

19. Improving the Health of and Access to Health Care for People With Disabilities: A Position Paper From the American College of Physicians.

作者: Katelan Cline.;Micah W Beachy.;Priscilla W Carr.; .
来源: Ann Intern Med. 2026年
In the United States, people with disabilities experience disparities in health and health care. Disparities stem from inadequate insurance coverage, physically and culturally inaccessible health care facilities, pervasive harmful misconceptions about disability, and incomprehensive epidemiologic data regarding disability. In this position paper, the American College of Physicians offers recommendations to alleviate health disparities among people with disabilities through policy changes in areas such as health insurance coverage, accessibility of health care facilities, health professional education, research participation, and data collection.

20. Atopic Dermatitis.

作者: Aaron Drucker.
来源: Ann Intern Med. 2026年179卷3期ITC33-ITC48页
Atopic dermatitis affects approximately 10% of the U.S. population and is more common in children than adults. Up to 99% of physician visits for atopic dermatitis are in primary care. Most cases can be managed successfully with topical treatments, including moisturizers and prescription anti-inflammatory treatments, such as corticosteroids, calcineurin inhibitors, phosphodiesterase-4 inhibitors, Janus kinase (JAK) inhibitors, and aryl hydrocarbon receptor agonists. For more refractory or severe atopic dermatitis, ultraviolet phototherapy and systemic treatments, usually prescribed by specialists, can be used. Systemic treatments include older off-label immunomodulators, such as methotrexate. Since 2017, multiple on-label injectable biologics and oral JAK inhibitors have been approved.
共有 977 条符合本次的查询结果, 用时 8.5364391 秒