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1481. In symptomatic adults undergoing high-resolution manometry, long-term opioid use was linked to esophageal dysmotility.
Niu C, Zhang J, Bapaye J, et al. Systematic review with meta-analysis: chronic opioid use is associated with esophageal dysmotility in symptomatic patients. Am J Gastroenterol. 18 Aug 2023. [Epub ahead of print]. 37463432.
1482. In acute MI complicated by cardiogenic shock, ECLS did not reduce 30-d all-cause mortality.
Thiele H, Zeymer U, Akin I, et al; ECLS-SHOCK Investigators. Extracorporeal life support in infarct-related cardiogenic shock. N Engl J Med. 2023;389:1286-1297. 37634145.
1483. USPSTF recommends PrEP using effective antiretroviral therapy in adults and adolescents at high risk for HIV.
US Preventive Services Task Force; Barry MJ, Nicholson WK, Silverstein M, et al. Preexposure prophylaxis to prevent acquisition of HIV: US Preventive Services Task Force Recommendation Statement. JAMA. 2023;330:736-745. 37606666.
1484. In RA in remission for >1 y, tapering TNFi to discontinuation did not meet noninferiority criteria compared with stable TNFi for disease flare at 12 mo.
Lillegraven S, Paulshus Sundlisaeter N, Aga AB, et al. Effect of tapered versus stable treatment with tumour necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non-inferiority trial. Ann Rheum Dis. 2023;82:1394-1403. 37607809.
1485. In symptomatic AF with end-stage HF, adding catheter ablation to medical therapy improved clinical outcomes at 18 mo.
Sohns C, Fox H, Marrouche NF, et al; CASTLE HTx Investigators. Catheter ablation in end-stage heart failure with atrial fibrillation. N Engl J Med. 2023;389:1380-1389. 37634135.
1486. Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.
作者: Rajiv Agarwal.;Wanzhu Tu.;Alfredo E Farjat.;Youssef M K Farag.;Robert Toto.;Sanjay Kaul.;Robert Lawatscheck.;Katja Rohwedder.;Luis M Ruilope.;Peter Rossing.;Bertram Pitt.;Gerasimos Filippatos.;Stefan D Anker.;George L Bakris.; .
来源: Ann Intern Med. 2023年176卷12期1606-1616页
In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown.
1487. Communicating the Value of Influenza Vaccines to Patients: Translating Vaccine Effectiveness to Acceptance.
作者: Mark W Tenforde.;Fatimah S Dawood.;Sascha R Ellington.;Lisa A Grohskopf.;Brendan Flannery.;Shikha Garg.;Carrie Reed.
来源: Ann Intern Med. 2023年176卷12期1670-1671页 1488. Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.
作者: Michael T Young.;Karen Jansen.;Kristen E Cosselman.;Timothy R Gould.;James A Stewart.;Timothy Larson.;Coralynn Sack.;Sverre Vedal.;Adam A Szpiro.;Joel D Kaufman.
来源: Ann Intern Med. 2023年176卷12期1586-1594页
Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes.
1489. Thyroidectomy for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms.
作者: Geir Hoff.;Tomm Bernklev.;Lene Johnsen.;Laurens Reitsma.;Dirk Sina.;Andromeda Lauzike.;Charlotte Gibbs.;Eivind Carlsen.;Tone Hoel Lende.;Jon Kristian Narvestad.;Rasmus Kildahl.;Roald Omdal.;Jan Terje Kvaløy.;Håvard Søiland.
来源: Ann Intern Med. 2024年177卷1期101-103页 1490. Two-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Donors With Hepatitis C Viremia to Recipients Without Hepatitis C Viremia: A Small Uncontrolled Trial.
作者: Niraj M Desai.;Sherry G Leung.;Jennifer D Motter.;Dorry L Segev.;Daniel Warren.;Christine M Durand.
来源: Ann Intern Med. 2023年176卷12期1682-1684页 1494. Cardiovascular Health of Middle-Aged U.S. Adults by Income Level, 1999 to March 2020 : A Serial Cross-Sectional Study.
作者: Michael Liu.;Rahul Aggarwal.;Zhaonian Zheng.;Robert W Yeh.;Dhruv S Kazi.;Karen E Joynt Maddox.;Rishi K Wadhera.
来源: Ann Intern Med. 2023年176卷12期1595-1605页
Although cardiovascular mortality has increased among middle-aged U.S. adults since 2011, how the burden of cardiovascular risk factors has changed for this population by income level over the past 2 decades is unknown.
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