4884. Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis.
作者: Steven R Ytterberg.;Deepak L Bhatt.;Ted R Mikuls.;Gary G Koch.;Roy Fleischmann.;Jose L Rivas.;Rebecca Germino.;Sujatha Menon.;Yanhui Sun.;Cunshan Wang.;Andrea B Shapiro.;Keith S Kanik.;Carol A Connell.; .
来源: N Engl J Med. 2022年386卷4期316-326页
Increases in lipid levels and cancers with tofacitinib prompted a trial of major adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis receiving tofacitinib as compared with a tumor necrosis factor (TNF) inhibitor.
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