4606. A Direct Measure of Tuberculosis Incidence - Effect of Community Screening.
作者: Guy B Marks.;Jennifer Ho.;Phuong Thi Bich Nguyen.;Thu Anh Nguyen.;Khanh Luu Boi.;Khoa Hien Tran.;Son Van Nguyen.;Nhung Viet Nguyen.;Hoa Binh Nguyen.;Linh Nhat Nguyen.;Frances L Garden.;Greg J Fox.
来源: N Engl J Med. 2022年386卷14期1380-1382页 4608. Intersectional Analysis of U.S. Medical Faculty Diversity over Four Decades.
作者: Sophia C Kamran.;Karen M Winkfield.;Joan Y Reede.;Neha Vapiwala.
来源: N Engl J Med. 2022年386卷14期1363-1371页
The 2020 U.S. Census data show a rapidly diversifying U.S. population. We sought to evaluate whether clinical faculty and leadership representation at academic medical schools reflects the diversifying population over time. Using data from the Association of American Medical Colleges for the period of 1977 through 2019, we found notable progress in female representation among clinical faculty, with smaller gains among department chairs and medical school deans. Racial and ethnic groups that are underrepresented in medicine are designated as such because their presence within the medical profession is disproportionate to the U.S. Census data. Even with accounting for this underrepresentation, clinical faculty and leadership positions show even starker disparities. Thoughtful policy implementation could help address this persistent underrepresentation among medical school faculty and leadership positions.
4615. Implanted System for Orthostatic Hypotension in Multiple-System Atrophy.
作者: Jordan W Squair.;Maxime Berney.;Mayte Castro Jimenez.;Nicolas Hankov.;Robin Demesmaeker.;Suje Amir.;Aurelie Paley.;Sergio Hernandez-Charpak.;Gregory Dumont.;Leonie Asboth.;Gilles Allenbach.;Fabio Becce.;Patrick Schoettker.;Gregoire Wuerzner.;Julien F Bally.;Grégoire Courtine.;Jocelyne Bloch.
来源: N Engl J Med. 2022年386卷14期1339-1344页
Orthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods. We implanted a system to restore regulation of blood pressure and enable a patient with multiple-system atrophy to stand and walk after having lost these abilities because of orthostatic hypotension. This system involved epidural electrical stimulation delivered over the thoracic spinal cord with accelerometers that detected changes in body position. (Funded by the Defitech Foundation.).
4616. Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.
作者: Paul B Eckburg.;Lori Muir.;Ian A Critchley.;Susannah Walpole.;Hanna Kwak.;Anne-Marie Phelan.;Gary Moore.;Akash Jain.;Tim Keutzer.;Aaron Dane.;David Melnick.;Angela K Talley.
来源: N Engl J Med. 2022年386卷14期1327-1338页
There is a need for oral antibiotic agents that are effective against multidrug-resistant gram-negative uropathogens. Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales, including extended-spectrum beta-lactamase-producing and fluoroquinolone-resistant strains.
4618. Protection with a Third Dose of mRNA Vaccine against SARS-CoV-2 Variants in Frontline Workers.
作者: Sarang K Yoon.;Kurt T Hegmann.;Matthew S Thiese.;Jefferey L Burgess.;Katherine Ellingson.;Karen Lutrick.;Lauren E W Olsho.;Laura J Edwards.;Brian Sokol.;Alberto J Caban-Martinez.;Natasha Schaefer-Solle.;John M Jones.;Harmony Tyner.;Angela Hunt.;Karley Respet.;Manjusha Gaglani.;Kayan Dunnigan.;Spencer Rose.;Allison Naleway.;Holly Groom.;Jennifer Kuntz.;Ashley L Fowlkes.;Mark G Thompson.;Young M Yoo.; .; .
来源: N Engl J Med. 2022年386卷19期1855-1857页 |