"N Engl J Med"[journal] 检索结果

4481. Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A.

作者: Margareth C Ozelo.;Johnny Mahlangu.;K John Pasi.;Adam Giermasz.;Andrew D Leavitt.;Michael Laffan.;Emily Symington.;Doris V Quon.;Jiaan-Der Wang.;Kathelijne Peerlinck.;Steven W Pipe.;Bella Madan.;Nigel S Key.;Glenn F Pierce.;Brian O'Mahony.;Radoslaw Kaczmarek.;Joshua Henshaw.;Adebayo Lawal.;Kala Jayaram.;Mei Huang.;Xinqun Yang.;Wing Y Wong.;Benjamin Kim.; .
来源: N Engl J Med. 2022年386卷11期1013-1025页

Valoctocogene roxaparvovec (AAV5-hFVIII-SQ) is an adeno-associated virus 5 (AAV5)-based gene-therapy vector containing a coagulation factor VIII complementary DNA driven by a liver-selective promoter. The efficacy and safety of the therapy were previously evaluated in men with severe hemophilia A in a phase 1-2 dose-escalation study.

4482. What's in a Number? Breaking Down the Residency Match Rate.

作者: Nicole M Mott.;J Bryan Carmody.;David A Marzano.;Maya M Hammoud.
来源: N Engl J Med. 2022年386卷17期1583-1586页

4483. Neutralization of the SARS-CoV-2 Omicron BA.1 and BA.2 Variants.

作者: Jingyou Yu.;Ai-Ris Y Collier.;Marjorie Rowe.;Fatima Mardas.;John D Ventura.;Huahua Wan.;Jessica Miller.;Olivia Powers.;Benjamin Chung.;Mazuba Siamatu.;Nicole P Hachmann.;Nehalee Surve.;Felix Nampanya.;Abishek Chandrashekar.;Dan H Barouch.
来源: N Engl J Med. 2022年386卷16期1579-1580页

4484. Molnupiravir for Covid-19 in Nonhospitalized Patients. Reply.

作者: Carisa De Anda.;Matthew G Johnson.;Alison Pedley.
来源: N Engl J Med. 2022年386卷13期e32页

4485. Molnupiravir for Covid-19 in Nonhospitalized Patients.

作者: Dominique Roberfroid.;Vicky Jespers.;Frank Hulstaert.
来源: N Engl J Med. 2022年386卷13期e32页

4486. Molnupiravir for Covid-19 in Nonhospitalized Patients.

作者: Susan Levenstein.
来源: N Engl J Med. 2022年386卷13期e32页

4487. Molnupiravir for Covid-19 in Nonhospitalized Patients.

作者: Pablo Selvi-Sabater.;Juan Abellon-Ruiz.
来源: N Engl J Med. 2022年386卷13期e32页

4488. Molnupiravir for Covid-19 in Nonhospitalized Patients.

作者: Kristian Thorlund.;Kyle Sheldrick.;Edward Mills.
来源: N Engl J Med. 2022年386卷13期e32页

4489. Where Americans Die - Is There Really "No Place Like Home"?

作者: Melissa W Wachterman.;Elizabeth A Luth.;Robert S Semco.;Joel S Weissman.
来源: N Engl J Med. 2022年386卷11期1008-1010页

4490. The Patient Resident.

作者: Natasha Z Rabinowitz Steele.
来源: N Engl J Med. 2022年386卷11期1010-1011页

4491. Pneumatosis Intestinalis in Necrotizing Enterocolitis.

作者: Lorraine Tong.;Yu-Tang Chang.
来源: N Engl J Med. 2022年386卷11期1070页

4492. A Malaria Vaccine for Africa - An Important Step in a Century-Long Quest.

作者: Pedro L Alonso.;Katherine L O'Brien.
来源: N Engl J Med. 2022年386卷11期1005-1007页

4493. Unclouded Judgment - Global Health and the Moral Clarity of Paul Farmer.

作者: Lisa Rosenbaum.
来源: N Engl J Med. 2022年386卷15期1470-1474页

4494. Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2.

作者: Emi Takashita.;Noriko Kinoshita.;Seiya Yamayoshi.;Yuko Sakai-Tagawa.;Seiichiro Fujisaki.;Mutsumi Ito.;Kiyoko Iwatsuki-Horimoto.;Peter Halfmann.;Shinji Watanabe.;Kenji Maeda.;Masaki Imai.;Hiroaki Mitsuya.;Norio Ohmagari.;Makoto Takeda.;Hideki Hasegawa.;Yoshihiro Kawaoka.
来源: N Engl J Med. 2022年386卷15期1475-1477页

4495. Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar.

作者: Laith J Abu-Raddad.;Hiam Chemaitelly.;Houssein H Ayoub.;Sawsan AlMukdad.;Hadi M Yassine.;Hebah A Al-Khatib.;Maria K Smatti.;Patrick Tang.;Mohammad R Hasan.;Peter Coyle.;Zaina Al-Kanaani.;Einas Al-Kuwari.;Andrew Jeremijenko.;Anvar H Kaleeckal.;Ali N Latif.;Riyazuddin M Shaik.;Hanan F Abdul-Rahim.;Gheyath K Nasrallah.;Mohamed Ghaith Al-Kuwari.;Adeel A Butt.;Hamad Eid Al-Romaihi.;Mohamed H Al-Thani.;Abdullatif Al-Khal.;Roberto Bertollini.
来源: N Engl J Med. 2022年386卷19期1804-1816页

Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and the emergence of the omicron (or B.1.1.529) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to expedited efforts to scale up booster vaccination. Protection conferred by booster doses of the BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) vaccines in Qatar, as compared with protection conferred by the two-dose primary series, is unclear.

4496. Hyperimmune Globulin for Congenital Cytomegalovirus Infection. Reply.

作者: Brenna L Hughes.;Dwight J Rouse.;Rebecca G Clifton.
来源: N Engl J Med. 2022年386卷10期1003页

4497. Hyperimmune Globulin for Congenital Cytomegalovirus Infection.

作者: Giovanni Nigro.
来源: N Engl J Med. 2022年386卷10期1002-1003页

4498. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection. Reply.

作者: Louis Bernard.;Agnès Caille.
来源: N Engl J Med. 2022年386卷10期1002页

4499. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection.

作者: Berardo Di Matteo.;Maurilio Marcacci.
来源: N Engl J Med. 2022年386卷10期1001-1002页

4500. Audio Interview: Making Covid-19 Vaccines Available around the World.

作者: Eric J Rubin.;Lindsey R Baden.;David Hunter.;Stephen Morrissey.
来源: N Engl J Med. 2022年386卷10期e31页

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