4468. Mpox in people with advanced HIV infection: a global case series.
作者: Oriol Mitjà.;Andrea Alemany.;Michael Marks.;Jezer I Lezama Mora.;Juan Carlos Rodríguez-Aldama.;Mayara Secco Torres Silva.;Ever Arturo Corral Herrera.;Brenda Crabtree-Ramirez.;José Luis Blanco.;Nicolo Girometti.;Valentina Mazzotta.;Aniruddha Hazra.;Macarena Silva.;Juan José Montenegro-Idrogo.;Kelly Gebo.;Jade Ghosn.;María Fernanda Peña Vázquez.;Eduardo Matos Prado.;Uche Unigwe.;Judit Villar-García.;Noah Wald-Dickler.;Jason Zucker.;Roger Paredes.;Alexandra Calmy.;Laura Waters.;Cristina Galvan-Casas.;Sharon Walmsley.;Chloe M Orkin.; .
来源: Lancet. 2023年401卷10380期939-949页
People living with HIV have accounted for 38-50% of those affected in the 2022 multicountry mpox outbreak. Most reported cases were in people who had high CD4 cell counts and similar outcomes to those without HIV. Emerging data suggest worse clinical outcomes and higher mortality in people with more advanced HIV. We describe the clinical characteristics and outcomes of mpox in a cohort of people with HIV and low CD4 cell counts (CD4 <350 cells per mm3).
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