4431. Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.
作者: Yao-Chung Liu.;Junsu Kwon.;Emiliano Fabiani.;Zhijian Xiao.;Yanjing V Liu.;Matilde Y Follo.;Jinqin Liu.;Huijun Huang.;Chong Gao.;Jun Liu.;Giulia Falconi.;Lia Valentini.;Carmelo Gurnari.;Carlo Finelli.;Lucio Cocco.;Jin-Hwang Liu.;Adrianna I Jones.;Junyu Yang.;Henry Yang.;Julie A I Thoms.;Ashwin Unnikrishnan.;John E Pimanda.;Rongqing Pan.;Mahmoud A Bassal.;Maria T Voso.;Daniel G Tenen.;Li Chai.
来源: N Engl J Med. 2022年386卷21期1998-2010页
Although hypomethylating agents are currently used to treat patients with cancer, whether they can also reactivate and up-regulate oncogenes is not well elucidated.
4436. Omicron BA.1/1.1 SARS-CoV-2 Infection among Vaccinated Canadian Adults.
作者: Patrick E Brown.;Sze Hang Fu.;Aiyush Bansal.;Leslie Newcombe.;Karen Colwill.;Geneviève Mailhot.;Melanie Delgado-Brand.;Anne-Claude Gingras.;Arthur S Slutsky.;Maria Pasic.;Jeffrey Companion.;Isaac I Bogoch.;Ed Morawski.;Teresa Lam.;Angus Reid.;Prabhat Jha.; .; .
来源: N Engl J Med. 2022年386卷24期2337-2339页 4439. Neutralization of the SARS-CoV-2 Deltacron and BA.3 Variants.
作者: John P Evans.;Panke Qu.;Cong Zeng.;Yi-Min Zheng.;Claire Carlin.;Joseph S Bednash.;Gerard Lozanski.;Rama K Mallampalli.;Linda J Saif.;Eugene M Oltz.;Peter J Mohler.;Richard J Gumina.;Shan-Lu Liu.
来源: N Engl J Med. 2022年386卷24期2340-2342页 |