当前位置: 首页 >> 检索结果
4383. Psychosocial Functioning in Transgender Youth after 2 Years of Hormones.
作者: Diane Chen.;Johnny Berona.;Yee-Ming Chan.;Diane Ehrensaft.;Robert Garofalo.;Marco A Hidalgo.;Stephen M Rosenthal.;Amy C Tishelman.;Johanna Olson-Kennedy.
来源: N Engl J Med. 2023年388卷3期240-250页
Limited prospective outcome data exist regarding transgender and nonbinary youth receiving gender-affirming hormones (GAH; testosterone or estradiol).
4384. Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.
作者: Lipika Goyal.;Funda Meric-Bernstam.;Antoine Hollebecque.;Juan W Valle.;Chigusa Morizane.;Thomas B Karasic.;Thomas A Abrams.;Junji Furuse.;Robin K Kelley.;Philippe A Cassier.;Heinz-Josef Klümpen.;Heung-Moon Chang.;Li-Tzong Chen.;Josep Tabernero.;Do-Youn Oh.;Amit Mahipal.;Markus Moehler.;Edith P Mitchell.;Yoshito Komatsu.;Kunihiro Masuda.;Daniel Ahn.;Robert S Epstein.;Abdel-Baset Halim.;Yao Fu.;Tehseen Salimi.;Volker Wacheck.;Yaohua He.;Mei Liu.;Karim A Benhadji.;John A Bridgewater.; .
来源: N Engl J Med. 2023年388卷3期228-239页
Alterations in fibroblast growth factor receptor 2 (FGFR2) have emerged as promising drug targets for intrahepatic cholangiocarcinoma, a rare cancer with a poor prognosis. Futibatinib, a next-generation, covalently binding FGFR1-4 inhibitor, has been shown to have both antitumor activity in patients with FGFR-altered tumors and strong preclinical activity against acquired resistance mutations associated with ATP-competitive FGFR inhibitors.
4385. Bivalent Omicron BA.1-Adapted BNT162b2 Booster in Adults Older than 55 Years.
作者: Patricia Winokur.;Juleen Gayed.;David Fitz-Patrick.;Stephen J Thomas.;Oyeniyi Diya.;Stephen Lockhart.;Xia Xu.;Ying Zhang.;Vishva Bangad.;Howard I Schwartz.;Douglas Denham.;Jose F Cardona.;Lisa Usdan.;John Ginis.;Federico J Mensa.;Jing Zou.;Xuping Xie.;Pei-Yong Shi.;Claire Lu.;Sandra Buitrago.;Ingrid L Scully.;David Cooper.;Kenneth Koury.;Kathrin U Jansen.;Özlem Türeci.;Uğur Şahin.;Kena A Swanson.;William C Gruber.;Nicholas Kitchin.; .
来源: N Engl J Med. 2023年388卷3期214-227页
The emergence of immune-escape variants of severe acute respiratory syndrome coronavirus 2 warrants the use of sequence-adapted vaccines to provide protection against coronavirus disease 2019.
4386. Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture.
作者: .;Robert V O'Toole.;Deborah M Stein.;Nathan N O'Hara.;Katherine P Frey.;Tara J Taylor.;Daniel O Scharfstein.;Anthony R Carlini.;Kuladeep Sudini.;Yasmin Degani.;Gerard P Slobogean.;Elliott R Haut.;William Obremskey.;Reza Firoozabadi.;Michael J Bosse.;Samuel Z Goldhaber.;Debra Marvel.;Renan C Castillo.
来源: N Engl J Med. 2023年388卷3期203-213页
Clinical guidelines recommend low-molecular-weight heparin for thromboprophylaxis in patients with fractures, but trials of its effectiveness as compared with aspirin are lacking.
4387. Protection against Reinfection with the Omicron BA.2.75 Subvariant.
作者: Hiam Chemaitelly.;Patrick Tang.;Peter Coyle.;Hadi M Yassine.;Hebah A Al-Khatib.;Maria K Smatti.;Mohammad R Hasan.;Houssein H Ayoub.;Heba N Altarawneh.;Zaina Al-Kanaani.;Einas Al-Kuwari.;Andrew Jeremijenko.;Anvar H Kaleeckal.;Ali N Latif.;Riyazuddin M Shaik.;Hanan F Abdul-Rahim.;Gheyath K Nasrallah.;Mohamed G Al-Kuwari.;Adeel A Butt.;Hamad E Al-Romaihi.;Mohamed H Al-Thani.;Abdullatif Al-Khal.;Roberto Bertollini.;Laith J Abu-Raddad.; .
来源: N Engl J Med. 2023年388卷7期665-667页 4388. Use of Wastewater for Mpox Outbreak Surveillance in California.
作者: Marlene K Wolfe.;Alexander T Yu.;Dorothea Duong.;Madhura S Rane.;Bridgette Hughes.;Vikram Chan-Herur.;Marisa Donnelly.;Shua Chai.;Bradley J White.;Duc J Vugia.;Alexandria B Boehm.
来源: N Engl J Med. 2023年388卷6期570-572页 4389. Substantial Neutralization Escape by SARS-CoV-2 Omicron Variants BQ.1.1 and XBB.1.
作者: Jessica Miller.;Nicole P Hachmann.;Ai-Ris Y Collier.;Ninaad Lasrado.;Camille R Mazurek.;Robert C Patio.;Olivia Powers.;Nehalee Surve.;James Theiler.;Bette Korber.;Dan H Barouch.
来源: N Engl J Med. 2023年388卷7期662-664页 |