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4341. The assessment of presenteeism and activity impairment in Behçet's syndrome and recurrent aphthous stomatitis: a multicentre study.
作者: Umit Karacayli.;Adebowale Adesanya.;Aysun Aksoy.;Joice M F M Belem.;Natália Borges Cardin.;Fatma Busra Sarı.;Tuğba Emine Beyhan.;Zülal Çelik.;Ceren Karacayli.;Fatma Alibaz-Öner.;Nevsun Inanç.;Tülin Ergun.;Meral Yay.;Wafa Madanat.;Alexandre Wagner Silva de Souza.;Farida Fortune.;Haner Direskeneli.;Gonca Mumcu.
来源: Rheumatology (Oxford). 2022年61卷4期1538-1547页
To evaluate key factors for presenteeism and activity impairment in multinational patients with Behçet's syndrome (BS) and recurrent aphthous stomatitis (RAS).
4342. Effect of statins on the prevention of recurrent thrombosis in thrombotic antiphospholipid syndrome.
To assess the effect of statins on the prevention of recurrent thrombosis in patients with thrombotic APS.
4344. Axonal dysfunction is associated with interferon-γ levels in childhood-onset systemic lupus erythematosus: a multivoxel magnetic resonance spectroscopy study.
作者: Renan Bazuco Frittoli.;Danilo Rodrigues Pereira.;Aline Tamires Lapa.;Mariana Postal.;Nailu Angelica Sinicato.;Paula Teixeira Fernandes.;Fernando Cendes.;Gabriela Castellano.;Leticia Rittner.;Roberto Marini.;Timothy B Niewold.;Simone Appenzeller.
来源: Rheumatology (Oxford). 2022年61卷4期1529-1537页
Axonal/neuronal damage has been shown to be a pathological finding that precedes neuropsychiatric manifestations in SLE. The objective of this study was to determine the presence of axonal dysfunction in childhood-onset SLE patients (cSLE) and to determine clinical, immunological and treatment features associated with its occurrence.
4345. Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia.
作者: Yuta Yamashita.;Yasuhiko Yamano.;Yoshinao Muro.;Mariko Ogawa-Momohara.;Takuya Takeichi.;Yasuhiro Kondoh.;Masashi Akiyama.
来源: Rheumatology (Oxford). 2022年61卷4期1709-1716页
Anti-NOR90 antibodies are usually found in patients with SSc; however, their clinical relevance remains obscure. We developed an ELISA for measuring them to investigate the clinical features of patients with anti-NOR90 antibodies.
4346. Hospital readmission in systemic sclerosis associated pulmonary hypertension: Results from the PHAROS registry.
作者: Kimberly Showalter.;Laura C Pinheiro.;Deanna Jannat-Khah.;Irina Sobol.;Jackie Szymonifka.;Jackie Finik.;Virginia D Steen.;Jessica K Gordon.
来源: Rheumatology (Oxford). 2022年61卷4期1510-1517页
To identify individual-level factors associated with hospital readmission among individuals with SSc-associated pulmonary hypertension (SSc-PH).
4347. First pilot study of extracellular volume MRI measurement in peripheral muscle of systemic sclerosis patients suggests diffuse fibrosis.
作者: Raluca B Dumitru.;Alex F Goodall.;David A Broadbent.;Francesco Del Galdo.;Ai Lyn Tan.;John D Biglands.;Maya H Buch.
来源: Rheumatology (Oxford). 2022年61卷4期1651-1657页
Peripheral muscle involvement in SSc may comprise myositis or a non-inflammatory myopathy. There is little understanding of the nature of SSc myopathy. This pilot study aimed to evaluate the presence of diffuse fibrosis in the peripheral muscle of patients with SSc by determining extracellular volume (ECV) MRI measurement.
4348. Subjective loss of clinical response to TNFi in axSpA relates to recurrence of MRI bone marrow oedema particularly with long-acting agents.
作者: Stephanie R Harrison.;Rebecca Ansell.;Hannah R Mathieson.;Mira Merashli.;Noemi Busquets-Pérez.;Dennis McGonagle.;Helena Marzo-Ortega.
来源: Rheumatology (Oxford). 2022年61卷SI期SI86-SI91页
Subjective loss of response immediately prior to routine TNFi therapy can occur in axial spondyloarthritis (axSpA). We investigated clinical outcomes in patients taking the first three licenced TNFis and correlated this with recurrence of MRI bone marrow oedema (MRI-BMO).
4349. OBSIDIAN - real-world evidence of originator to biosimilar drug switch in juvenile idiopathic arthritis.
作者: Ilaria Maccora.;Niccolò Lombardi.;Giada Crescioli.;Alessandra Bettiol.;Roberto Bonaiuti.;Ilaria Pagnini.;Valerio Maniscalco.;Edoardo Marrani.;Maria Vincenza Mastrolia.;Claudia Ravaldi.;Rita Consolini.;Marco Cattalini.;Alfredo Vannacci.;Gabriele Simonini.
来源: Rheumatology (Oxford). 2022年61卷4期1518-1528页
Limited data about use of biosimilars (BIOs) are available in children with JIA. This study therefore aimed to evaluate long-term efficacy and safety of switching from etanercept (ETA) and adalimumab (ADA) originators to their biosimilars (BIOs), in children with JIA, in a real-world setting.
4350. Factors associated with remission at 5-year follow-up in recent-onset axial spondyloarthritis: results from the DESIR cohort.
作者: Laura Pina Vegas.;Emilie Sbidian.;Daniel Wendling.;Philippe Goupille.;Salah Ferkal.;Philippe Le Corvoisier.;Bijan Ghaleh.;Alain Luciani.;Pascal Claudepierre.
来源: Rheumatology (Oxford). 2022年61卷4期1487-1495页
The factors contributing to long-term remission in axial SpA (axSpA) are unclear. We aimed to characterize individuals with axSpA at the 5-year follow-up to identify baseline factors associated with remission.
4351. Socio-demographic determinants in the evolution of pain in inflammatory rheumatic diseases: results from ESPOIR and DESIR cohorts.
作者: Sushmithadev Kumaradev.;Christian Roux.;Jérémie Sellam.;Serge Perrot.;Thao Pham.;Aline Dugravot.;Anna Molto.
来源: Rheumatology (Oxford). 2022年61卷4期1496-1509页
To determine whether socio-demographic factors are associated with heterogeneity in pain evolution in inflammatory rheumatic diseases (IRDs) after accounting for disease-specific characteristics in a system with universal health care.
4355. Real-time vs static scoring in musculoskeletal ultrasonography in patients with inflammatory hand osteoarthritis.
作者: Lotte A van de Stadt.;Féline P B Kroon.;Frits R Rosendaal.;Desirée van der Heijde.;Monique Reijnierse.;Naghmeh Riyazi.;Ragnhild de Slegte.;Jendé van Zeben.;Cornelia F Allaart.;Margreet Kloppenburg.;Marion C Kortekaas.
来源: Rheumatology (Oxford). 2022年61卷SI期SI65-SI72页
Agreement between real-time and static ultrasonography has not been studied in musculoskeletal diseases. We studied this agreement in inflammatory hand OA.
4357. Limb girdle muscular dystrophy R12 (LGMD 2L, anoctaminopathy) mimicking idiopathic inflammatory myopathy: key points to prevent misdiagnosis.
作者: Italo Marago.;Mark Roberts.;Federico Roncaroli.;Daniel DuPlessis.;Caroline Sewry.;Santhosh Nagaraju.;Faheema Limbada.;Chiara Marini-Bettolo.;Judith Hudson.;Siwalik Banerjee.;Laura Newton.;Marwan Bukhari.;Hector Chinoy.;James B Lilleker.
来源: Rheumatology (Oxford). 2022年61卷4期1645-1650页
Diagnosing the idiopathic inflammatory myopathies (IIMs) can be challenging as several conditions, including genetic myopathies such as limb girdle muscular dystrophy type R12 (LGMD 2 l, anoctaminopathy) mimic the presentation. Here we describe learning points identified from review of four patients with LGMD 2 l who were initially incorrectly diagnosed with IIM. Our aim is to provide clinicians working in adult rheumatology services with a toolkit to help identify non-inflammatory presentations of myopathy.
4358. Evidence and consensus-based recommendations for non-pharmacological treatment of fatigue, hand function loss, Raynaud's phenomenon and digital ulcers in patients with systemic sclerosis.
作者: Juliane K Stöcker.;Anne A Schouffoer.;Julia Spierings.;Marisca R Schriemer.;Judith Potjewijd.;Lian de Pundert.;Frank H J van den Hoogen.;Maria W G Nijhuis-van der Sanden.;J Bart Staal.;Ton Satink.;Madelon C Vonk.;Cornelia H M van den Ende.; .
来源: Rheumatology (Oxford). 2022年61卷4期1476-1486页
SSc is a complex CTD affecting mental and physical health. Fatigue, hand function loss, and RP are the most prevalent disease-specific symptoms of systemic sclerosis. This study aimed to develop consensus and evidence-based recommendations for non-pharmacological treatment of these symptoms.
4360. Expansion of CD4+CD8+ double-positive T cells in rheumatoid arthritis patients is associated with erosive disease.
作者: Phuong Nguyen.;Marc Melzer.;Felix Beck.;Marco Krasselt.;Olga Seifert.;Matthias Pierer.;Kathrin Rothe.;Ulf Wagner.
来源: Rheumatology (Oxford). 2022年61卷3期1282-1287页
CD4+CD8+ double-positive (DP) T cells are expanded in the peripheral blood of a subset of patients with RA. This study examines the clinical significance of DP T cells in RA.
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