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4162. Endoscopist Characteristics and Polyp Detection in Colonoscopy: Cross-Sectional Analyses of Screening of Swedish Colons.
作者: Masau Sekiguchi.;Marcus Westerberg.;Anders Ekbom.;Rolf Hultcrantz.;Anna Forsberg.
来源: Gastroenterology. 2023年164卷2期293-295.e4页 4164. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts.
作者: Alessandro Paniccia.;Patricio M Polanco.;Brian A Boone.;Abigail I Wald.;Kevin McGrath.;Randall E Brand.;Asif Khalid.;Nisa Kubiliun.;Anne Marie O'Broin-Lennon.;Walter G Park.;Jason Klapman.;Benjamin Tharian.;Sumant Inamdar.;Kenneth Fasanella.;John Nasr.;Jennifer Chennat.;Rohit Das.;John DeWitt.;Jeffrey J Easler.;Benjamin Bick.;Harkirat Singh.;Kimberly J Fairley.;Savreet Sarkaria.;Tarek Sawas.;Wasseem Skef.;Adam Slivka.;Anna Tavakkoli.;Shyam Thakkar.;Victoria Kim.;Hendrikus Dutch Vanderveldt.;Allyson Richardson.;Michael B Wallace.;Bhaumik Brahmbhatt.;Megan Engels.;Charles Gabbert.;Mohannad Dugum.;Samer El-Dika.;Yasser Bhat.;Sanjay Ramrakhiani.;Gennadiy Bakis.;Daniil Rolshud.;Gordon Millspaugh.;Thomas Tielleman.;Carl Schmidt.;John Mansour.;Wallis Marsh.;Melanie Ongchin.;Barbara Centeno.;Sara E Monaco.;N Paul Ohori.;Sigfred Lajara.;Elizabeth D Thompson.;Ralph H Hruban.;Phoenix D Bell.;Katelyn Smith.;Jennifer B Permuth.;Christopher Vandenbussche.;Wayne Ernst.;Maria Grupillo.;Cihan Kaya.;Melissa Hogg.;Jin He.;Christopher L Wolfgang.;Kenneth K Lee.;Herbert Zeh.;Amer Zureikat.;Marina N Nikiforova.;Aatur D Singhi.
来源: Gastroenterology. 2023年164卷1期117-133.e7页
Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful adjunct in the assessment of patients with pancreatic cyst. However, previous studies have been retrospective or single institutional experiences. The aim of this study was to prospectively evaluate NGS on a multi-institutional cohort of patients with pancreatic cyst in real time.
4167. Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.
作者: Dongni Fu.;Brandon M Blobner.;Phil J Greer.;Robert Lafyatis.;Melena D Bellin.;David C Whitcomb.; .; .; .
来源: Gastroenterology. 2023年164卷2期289-292.e4页 4169. Unfermented β-fructan Fibers Fuel Inflammation in Select Inflammatory Bowel Disease Patients.
作者: Heather K Armstrong.;Michael Bording-Jorgensen.;Deanna M Santer.;Zhengxiao Zhang.;Rosica Valcheva.;Aja M Rieger.;Justin Sung-Ho Kim.;Stephanie I Dijk.;Ramsha Mahmood.;Olamide Ogungbola.;Juan Jovel.;France Moreau.;Hayley Gorman.;Robyn Dickner.;Jeremy Jerasi.;Inderdeep K Mander.;Dawson Lafleur.;Christopher Cheng.;Alexandra Petrova.;Terri-Lyn Jeanson.;Andrew Mason.;Consolato M Sergi.;Arie Levine.;Kris Chadee.;David Armstrong.;Sarah Rauscher.;Charles N Bernstein.;Matthew W Carroll.;Hien Q Huynh.;Jens Walter.;Karen L Madsen.;Levinus A Dieleman.;Eytan Wine.
来源: Gastroenterology. 2023年164卷2期228-240页
Inflammatory bowel diseases (IBD) are affected by dietary factors, including nondigestible carbohydrates (fibers), which are fermented by colonic microbes. Fibers are overall beneficial, but not all fibers are alike, and some patients with IBD report intolerance to fiber consumption. Given reproducible evidence of reduced fiber-fermenting microbes in patients with IBD, we hypothesized that fibers remain intact in select patients with reduced fiber-fermenting microbes and can then bind host cell receptors, subsequently promoting gut inflammation.
4173. Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation.
作者: Honggui Li.;Juan Zheng.;Qian Xu.;Yongjian Yang.;Jing Zhou.;Xinlei Guo.;Yongfeng Cai.;James J Cai.;Linglin Xie.;Joseph Awika.;Xianlin Han.;Qingsheng Li.;Lindsey Kennedy.;Heather Francis.;Shannon Glaser.;Yuqing Huo.;Gianfranco Alpini.;Chaodong Wu.
来源: Gastroenterology. 2023年164卷1期134-146页
Nonalcoholic fatty liver disease is highly associated with obesity and progresses to nonalcoholic steatohepatitis when the liver develops overt inflammatory damage. While removing adenosine in the purine salvage pathway, adenosine kinase (ADK) regulates methylation reactions. We aimed to study whether hepatocyte ADK functions as an obesogenic gene/enzyme to promote excessive fat deposition and liver inflammation.
4176. Reappraisal of Coronavirus Disease 2019 Risk for Patients With Inflammatory Bowel Disease: Withdrawal of the British Society of Gastroenterology Inflammatory Bowel Disease Risk Grid. |