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4062. Anti-PM-Scl antibodies-positive patients encompass three different groups with distinct prognoses.
作者: Paul Breillat.;Kuberaka Mariampillai.;Paul Legendre.;Pauline Martins.;Bertrand Dunogue.;Jean Luc Charuel.;Makoto Miyara.;Claire Goulvestre.;Romain Paule.;Helene Vanquaethem.;Felix Ackermann.;Olivier Benveniste.;Hilario Nunes.;Luc Mouthon.;Yves Allenbach.;Yurdagul Uzunhan.
来源: Rheumatology (Oxford). 2023年62卷4期1467-1475页
To help identify homogeneous subgroups among patients with anti-PM-scleroderma-antibodies (PM-Scl-Abs) positive auto-immune diseases regardless of diagnostic classifications.
4063. Flare-up of mucocutaneous leishmaniasis following infliximab discontinuation and antiparasitic therapy in a patient with juvenile idiopathic arthritis.
作者: Florent Amatore.;Floriane Lebas.;Aurélie Haffner.;Emmanuel Delaporte.
来源: Rheumatology (Oxford). 2023年62卷4期e138-e139页 4064. Dendritic cells drive profibrotic inflammation and aberrant T cell polarization in systemic sclerosis.
作者: José Alberto Choreño-Parra.;Diana Cervantes-Rosete.;Luis Armando Jiménez-Álvarez.;Gustavo Ramírez-Martínez.;José Eduardo Márquez-García.;Alfredo Cruz-Lagunas.;Ana Yelli Magaña-Sánchez.;Guadalupe Lima.;Humberto López-Maldonado.;Emanuel Gaytán-Guzmán.;Adrian Caballero.;Rosario Fernández-Plata.;Janette Furuzawa-Carballeda.;Criselda Mendoza-Milla.;Maria Del Carmen Navarro-González.;Luis Llorente.;Joaquín Zúñiga.;Tatiana Sofía Rodríguez-Reyna.
来源: Rheumatology (Oxford). 2023年62卷4期1687-1698页
SSc is a devastating autoimmune disease characterized by fibrosis and obliterative vasculopathy affecting the skin and visceral organs. While the processes mediating excessive extracellular matrix deposition and fibroblast proliferation are clear, the exact link between autoimmunity and fibrosis remains elusive. Th17 cells have been proposed as critical drivers of profibrotic inflammation during SSc, but little is known about the immune components supporting their pathogenic role. Our aim was to determine cytokine responses of stimulated monocyte-derived dendritic cells (Mo-DCs) and to determine how they influence T-cell cytokine production in SSc.
4066. Atypical polyarticular juvenile idiopathic arthritis revealing multicentric reticulohistiocytosis with pulmonary involvement.
作者: Anna Gaussem.;Perrine Dusser.;Van Huynh.;Caroline Galeotti.;Adrien Schvartz.;Léa Jaume.;Linda Rossi-Semerano.;Isabelle Koné-Paut.;Charlotte Borocco.
来源: Rheumatology (Oxford). 2023年62卷4期e122-e123页 4067. Predicting lymphoma in Sjögren's syndrome and the pathogenetic role of parotid microenvironment through precise parotid swelling recording.
作者: Salvatore De Vita.;Miriam Isola.;Chiara Baldini.;Andreas V Goules.;Loukas G Chatzis.;Luca Quartuccio.;Alen Zabotti.;Ivan Giovannini.;Valentina Donati.;Francesco Ferro.;Maria Teresa Rizzo.;Valeria Manfrè.;Enrico Pegolo.;Michael Voulgarelis.;Francesco Zaja.;Renato Fanin.;Christos Masaoutis.;Dimitra Rontogianni.;Dimitrios I Fotiadis.;Maurilio Ponzoni.;Athanasios G Tzioufas.
来源: Rheumatology (Oxford). 2023年62卷4期1586-1593页
Parotid swelling (PSW) is a major predictor of non-Hodgkin's lymphoma (NHL) in primary SS (pSS). However, since detailed information on the time of onset and duration of PSW is scarce, this was investigated to verify whether it may lead to further improved prediction. NHL localization was concomitantly studied to evaluate the role of the parotid gland microenvironment in pSS-related lymphomagenesis.
4068. Procalcitonin can increase during activation of adult-onset Still's disease (AOSD) in the absence of an ınfection focus.
作者: Reşit Yıldırım.;Sedanur Oğuzman.;Döndü Üsküdar Cansu.;Mustafa Dinler.;Cengiz Korkmaz.
来源: Rheumatology (Oxford). 2023年62卷4期e109-e110页 4070. A panel of plasma microRNAs improves the assessment of surrogate markers of cardiovascular disease in rheumatoid arthritis patients.
作者: Didac Llop.;Daiana Ibarretxe.;Núria Plana.;Roser Rosales.;Delia Taverner.;Lluís Masana.;Joan Carles Vallvé.;Silvia Paredes.
来源: Rheumatology (Oxford). 2023年62卷4期1677-1686页
Patients with RA present increased risk of cardiovascular (CV) disease compared with the general population. Moreover, CV risk factors that have a causal relationship with atherosclerosis do not seem to fully explain the accelerated process that they exhibit. We evaluated the association of a 10 microRNAs panel with surrogate markers of subclinical arteriosclerosis [carotid intima-media thickness (cIMT), carotid plaque presence (cPP), pulse wave velocity (PWV) and distensibility] in a cohort of RA patients.
4071. Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis.
作者: Georgina Nakafero.;Matthew J Grainge.;Tim Card.;Christian D Mallen.;Jonathan S Nguyen Van-Tam.;Hywel C Williams.;Abhishek Abhishek.
来源: Rheumatology (Oxford). 2023年62卷4期1445-1450页
To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and autoimmune rheumatic disease (AIRD) flare.
4072. DWI scalp dot sign: superficial temporal artery restricted diffusion in giant cell arteritis.
作者: Eleanor Taylor.;Francesca Tona.;Victoria Singh-Curry.;Marius Venter.;Maresa Carulli.;Colin Tench.;Taryn Youngstein.;Luke Dixon.
来源: Rheumatology (Oxford). 2023年62卷4期e119-e121页 4073. Longitudinal global transcriptomic profiling of preclinical systemic sclerosis reveals molecular changes associated with disease progression.
作者: Chiara Bellocchi.;Lorenzo Beretta.;Xuan Wang.;Marka A Lyons.;Maurizio Marchini.;Maurizio Lorini.;Vincenzo Carbonelli.;Nicola Montano.;Shervin Assassi.
来源: Rheumatology (Oxford). 2023年62卷4期1662-1668页
To investigate peripheral blood cell (PBCs) global gene expression profile of SSc at its preclinical stage (PreSSc) and to characterize the molecular changes associated with progression to a definite disease over time.
4074. Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.
作者: Rodrigo Coutinho de Almeida.;Margo Tuerlings.;Yolande Ramos.;Wouter Den Hollander.;Eka Suchiman.;Nico Lakenberg.;Rob G H H Nelissen.;Hailiang Mei.;Ingrid Meulenbelt.
来源: Rheumatology (Oxford). 2023年62卷4期1669-1676页
To present an unbiased approach to identify positional transcript single nucleotide polymorphisms (SNPs) of osteoarthritis (OA) risk loci by allelic expression imbalance (AEI) analyses using RNA sequencing of articular cartilage and subchondral bone from OA patients.
4075. A data-driven approach finds RNA polymerase III antibody and tendon friction rubs as enrichment tools for early diffuse scleroderma trials.
作者: Robyn T Domsic.;Thomas A Medsger.;Shiyao Gao.;Maureen Laffoon.;Suiyuan Huang.;Stephen Wisniewski.;Cathie Spino.;Virginia Steen.;Robert Lafyatis.;Dinesh Khanna.
来源: Rheumatology (Oxford). 2023年62卷4期1543-1551页
Clinical trials in early diffuse SSc have consistently shown a placebo group response with a declining modified Rodnan skin score (mRSS), with negative outcomes. Our objective was to identify strategies using clinical characteristics or laboratory values to improve trial design.
4077. Sustained glucocorticoid tapering in the phase 3 trials of anifrolumab: a post hoc analysis of the TULIP-1 and TULIP-2 trials.
作者: Ian N Bruce.;Ronald F van Vollenhoven.;Eric F Morand.;Richard A Furie.;Susan Manzi.;William B White.;Gabriel Abreu.;Raj Tummala.
来源: Rheumatology (Oxford). 2023年62卷4期1526-1534页
Glucocorticoid sparing is a key priority for SLE management. We evaluated the effects of sustained glucocorticoid tapering in patients with SLE.
4078. Impact of initial therapy with upadacitinib or adalimumab on achievement of 48-week treatment goals in patients with rheumatoid arthritis: post hoc analysis of SELECT-COMPARE.
作者: Eduardo Mysler.;Yoshiya Tanaka.;Arthur Kavanaugh.;Daniel Aletaha.;Peter C Taylor.;In-Ho Song.;Tim Shaw.;Yanna Song.;Ryan DeMasi.;Mira Ali.;Roy Fleischmann.
来源: Rheumatology (Oxford). 2023年62卷5期1804-1813页
Evaluate the importance of treatment sequencing in SELECT-COMPARE, assessing potential differences between starting upadacitinib or adalimumab therapy following inadequate MTX response.
4079. Standardized nailfold capillaroscopy in children with rheumatic diseases: a worldwide study.
作者: Karin Melsens.;Maurizio Cutolo.;Dieneke Schonenberg-Meinema.;Ivan Foeldvari.;Maria C Leone.;Yora Mostmans.;Valérie Badot.;Rolando Cimaz.;Joke Dehoorne.;Ellen Deschepper.;Tracy Frech.;Johanna Hernandez-Zapata.;Francesca Ingegnoli.;Archana Khan.;Dorota Krasowska.;Hartwig Lehmann.;Ashima Makol.;Miguel A Mesa-Navas.;Malgorzata Michalska-Jakubus.;Ulf Müller-Ladner.;Laura Nuño-Nuño.;Rebecca Overbury.;Carmen Pizzorni.;Mislav Radic.;Divya Ramadoss.;Angelo Ravelli.;Silvia Rosina.;Clara Udaondo.;Merlijn J van den Berg.;Ariane L Herrick.;Alberto Sulli.;Vanessa Smith.; .
来源: Rheumatology (Oxford). 2023年62卷4期1605-1615页
To standardly assess and describe nailfold videocapillaroscopy (NVC) assessment in children and adolescents with juvenile rheumatic and musculoskeletal diseases (jRMD) vs healthy controls (HCs).
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