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3861. Methylated Septin9 has moderate diagnostic value in colorectal cancer detection in Chinese population: a multicenter study.
作者: Dong-Cheng Lu.;Qi-Fang Zhang.;Li Li.;Xian-Ke Luo.;Bin Liang.;Yi-Han Lu.;Bang-Li Hu.;Hai-Xing Jiang.
来源: BMC Gastroenterol. 2022年22卷1期232页
The detection rate of methylated Septin9 (mSEPT9) in colorectal cancer (CRC) is varied greatly across the studies. This study aimed to evaluate the diagnostic ability of mSEPT9 in CRC, and compare the diagnostic efficacy with fecal immunochemical test (FIT).
3862. Characteristics of acute kidney injury and its impact on outcome in patients with acute-on-chronic liver failure.
作者: Yue Huang.;Junjun Cai.;Fushuang Ha.;Beichen Guo.;Shaojie Xin.;Zhongping Duan.;Tao Han.
来源: BMC Gastroenterol. 2022年22卷1期231页
Acute kidney injury (AKI) is a common and life-threatening complication of liver failure. The purpose of this study is to construct a nomogram and online calculator to predict the development of hospital-acquired acute kidney injury (HA-AKI) in patients with acute-on-chronic liver failure (ACLF), which may contribute to the prognosis of ACLF.
3863. Analysis of antiviral efficacy after switching from brand to generic entecavir in patients with treatment-naïve chronic hepatitis B.
Entecavir (ETV) can suppress chronic hepatitis B (CHB) virus replication as a standard of treatment drugs. For the treatment of CHB, affordable generic drugs may be more widely used in developing and undeveloped countries. However, there is little real-world data regarding the clinical efficacy of switching from entecavir-brand-name drugs (ETV-Brand) to entecavir generic drugs (ETV-Generic) with 0.5 mg once daily. The aim of the study was to evaluate the antiviral activity and safety of ETV-Generic in comparison to ETV-Brand in CHB-patients.
3864. Combination of serological biomarkers and clinical features to predict mucosal healing in Crohn's disease: a multicenter cohort study.
作者: Nana Tang.;Han Chen.;Ruidong Chen.;Wen Tang.;Hongjie Zhang.
来源: BMC Gastroenterol. 2022年22卷1期229页
Mucosal healing (MH) has become the treatment goal of patients with Crohn's disease (CD). This study aims to develop a noninvasive and reliable clinical tool for individual evaluation of mucosal healing in patients with Crohn's disease.
3865. Correction to: Typhoid fever presenting with gastric ulcer bleeding.
作者: Hong Jae Jeon.;Jong Seo Lee.;Byung Seok Lee.;Seok Hyun Kim.;Eaum Seok Lee.;Jae Kyu Sung.;Hee Seok Moon.;Sun Hyung Kang.;Hyun Seok Lee.;Seongwoo Choi.;Heon Sa-Kong.;Shinhye Cheon.;Hyuk Soo Eun.
来源: BMC Gastroenterol. 2022年22卷1期230页 3866. Opioid Exposure Differentially Impacts Esophageal Body Contraction Over the Lower Esophageal Sphincter.
作者: Dhyanesh A Patel.;James Goss.;Muhammad Hayat.;Claudio Tombazzi.;Rishi D Naik.;James C Slaughter.;Muhammad Aslam.;Shabnam Sarker.;Tina Higginbotham.;Michael F Vaezi.
来源: Gastroenterology. 2022年163卷2期403-410页
Studies with limited sample sizes have investigated association of chronic opioid use with motility disorders of esophagogastric junction and esophageal body peristalsis. Our aims were to use a large cohort of patients to assess (1) the impact of opioid exposure on clinical and manometric characteristics, and (2) the association of opioid exposure with higher long-term symptom burden.
3867. Anticoagulant drugs with or without proton pump inhibitor and colorectal cancer risk: a population-based, case-control study.
作者: Pei-Huan Ho.;Hung-Chun Hsiao.;Chun-Wei Chen.;Hui-Ming Chen.;Siew-Na Lim.;Chau-Ting Yeh.;Chia-Jung Kuo.;Wey-Ran Lin.
来源: BMC Gastroenterol. 2022年22卷1期225页
Low-dose aspirin and clopidogrel have demonstrated potential chemoprevention for colorectal cancer (CRC). Proton-pump inhibitors (PPI) are commonly prescribed with anticoagulation drugs, but the relationship between PPI and CRC is unclear. Moreover, evidence of CRC risk under direct oral anticoagulant (DOAC) is limited. This study aimed to investigate the effects of anticoagulation drugs combined with or without PPI on the risks of CRC in Taiwan.
3868. Signet-ring cell carcinoma of the duodenal bulb presenting with gastrointestinal hemorrhage: a case report and literature review.
Primary duodenal cancer (PDC) is rare, especially signet-ring cell carcinoma (SRCC) of the duodenal bulb, and it is commonly misdiagnosed as an ulceration. Here, we report a rare case of SRCC of the duodenal bulb presenting with gastrointestinal hemorrhage in an 82-year-old man.
3869. Neonatal cholestasis is an early liver manifestation of children with acid sphingomyelinase deficiency.
作者: Neng-Li Wang.;Jing Lin.;Lian Chen.;Yi Lu.;Xin-Bao Xie.;Kuerbanjiang Abuduxikuer.;Jian-She Wang.
来源: BMC Gastroenterol. 2022年22卷1期227页
Patients with acid sphingomyelinase deficiency (ASMD) may be referred to a hepatologist for liver manifestations. This study summarized the liver manifestations of patients with ASMD in the early disease course.
3870. Application of a novel scoring system for gastric cancer opportunistic screening in hospital visits.
作者: Qingjie Zhou.;Yihan Chen.;Jie Pan.;Leying Zhou.;Jiejun Lin.
来源: BMC Gastroenterol. 2022年22卷1期223页
A novel scoring system and screening procedure for gastric cancer (GC) screening was proposed based on the national conditions of China, which state that endoscopy professionals and facilities are relatively limited compared with the large Chinese population.
3871. Laparoscopic liver resection of segment 8 via a hepatic parenchymal transection-first approach guided by the middle hepatic vein.
Pure laparoscopic liver resection (LLR) of segment 8 (S8) is still rarely performed due to the lack of an appropriate surgical approach. This article discusses the technical tips and operation methods for LLR of S8 via a hepatic parenchymal transection-first approach.
3873. Common Genetic Variants in the Bile Acid Synthesis Enzyme CYP7A1 Are Associated With Severe Primary Bile Acid Diarrhea.
作者: Sara Balesaria.;Sanjeev S Pattni.;Ian M Johnston.;Jonathan D Nolan.;Richard N Appleby.;Julian R F Walters.
来源: Gastroenterology. 2022年163卷2期517-519.e2页 |