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3767. Marburg Virus Disease in Ghana.
作者: Joseph K Bonney.;Bright Adu.;Terrel Sanders.;Deborah Pratt.;Patience Adams.;Ivy A Asante.;Evelyn Y Bonney.;Bright Agbodzi.;Selassie Kumordjie.;Martin Faye.;Evangeline Obodai.;Prince Ketorwoley.;Clara Yeboah.;Mildred Tublu.;Moussa M Diagne.;Amadou Diallo.;Magdalene Ofori.;Dennis Laryea.;Franklin Asiedu-Bekoe.;George B Kyei.;Sally-Ann Ohene.;Gifty Boateng.;Ryan Chapman.;Ousmane Faye.;Michael Wiley.;John Odoom.;Amadou Sall.;Francis C Kasolo.;Dorothy Yeboah-Manu.
来源: N Engl J Med. 2023年388卷25期2393-2394页 3772. Second-Line Switch to Dolutegravir for Treatment of HIV Infection.
作者: Loice A Ombajo.;Jeremy Penner.;Joseph Nkuranga.;Jared Mecha.;Margaret Mburu.;Collins Odhiambo.;Florentius Ndinya.;Rukia Aksam.;Richard Njenga.;Simon Wahome.;Peter Muiruri.;Sheila Eshiwani.;Maureen Kimani.;Catherine Ngugi.;Anton Pozniak.
来源: N Engl J Med. 2023年388卷25期2349-2359页
Data to inform the switch from a ritonavir-boosted protease inhibitor (PI) to dolutegravir in patients living with human immunodeficiency virus (HIV) infection who do not have genotype information and who have viral suppression with second-line therapy containing a ritonavir-boosted PI have been limited.
3773. Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.
作者: Javier Bolaños-Meade.;Mehdi Hamadani.;Juan Wu.;Monzr M Al Malki.;Michael J Martens.;Lyndsey Runaas.;Hany Elmariah.;Andrew R Rezvani.;Mahasweta Gooptu.;Karilyn T Larkin.;Brian C Shaffer.;Najla El Jurdi.;Alison W Loren.;Melhem Solh.;Aric C Hall.;Amin M Alousi.;Omer H Jamy.;Miguel-Angel Perales.;Janny M Yao.;Kristy Applegate.;Ami S Bhatt.;Leslie S Kean.;Yvonne A Efebera.;Ran Reshef.;William Clark.;Nancy L DiFronzo.;Eric Leifer.;Mary M Horowitz.;Richard J Jones.;Shernan G Holtan.; .
来源: N Engl J Med. 2023年388卷25期2338-2348页
In patients undergoing allogeneic hematopoietic stem-cell transplantation (HSCT), a calcineurin inhibitor plus methotrexate has been a standard prophylaxis against graft-versus-host disease (GVHD). A phase 2 study indicated the potential superiority of a post-transplantation regimen of cyclophosphamide, tacrolimus, and mycophenolate mofetil.
3777. Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults.
作者: Matthew E Prekker.;Brian E Driver.;Stacy A Trent.;Daniel Resnick-Ault.;Kevin P Seitz.;Derek W Russell.;John P Gaillard.;Andrew J Latimer.;Shekhar A Ghamande.;Kevin W Gibbs.;Derek J Vonderhaar.;Micah R Whitson.;Christopher R Barnes.;Jeremy P Walco.;Ivor S Douglas.;Vijay Krishnamoorthy.;Alon Dagan.;Jill J Bastman.;Bradley D Lloyd.;Sheetal Gandotra.;Jordan K Goranson.;Steven H Mitchell.;Heath D White.;Jessica A Palakshappa.;Alyssa Espinera.;David B Page.;Aaron Joffe.;Sydney J Hansen.;Christopher G Hughes.;Tobias George.;J Taylor Herbert.;Nathan I Shapiro.;Steven G Schauer.;Brit J Long.;Brant Imhoff.;Li Wang.;Jillian P Rhoads.;Kelsey N Womack.;David R Janz.;Wesley H Self.;Todd W Rice.;Adit A Ginde.;Jonathan D Casey.;Matthew W Semler.; .
来源: N Engl J Med. 2023年389卷5期418-429页
Whether video laryngoscopy as compared with direct laryngoscopy increases the likelihood of successful tracheal intubation on the first attempt among critically ill adults is uncertain.
3778. Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure.
作者: Peter J Blankestijn.;Robin W M Vernooij.;Carinna Hockham.;Giovanni F M Strippoli.;Bernard Canaud.;Jörgen Hegbrant.;Claudia Barth.;Adrian Covic.;Krister Cromm.;Andrea Cucui.;Andrew Davenport.;Matthias Rose.;Marietta Török.;Mark Woodward.;Michiel L Bots.; .
来源: N Engl J Med. 2023年389卷8期700-709页
Several studies have suggested that patients with kidney failure may benefit from high-dose hemodiafiltration as compared with standard hemodialysis. However, given the limitations of the various published studies, additional data are needed.
3779. Cardiovascular Safety of Testosterone-Replacement Therapy.
作者: A Michael Lincoff.;Shalender Bhasin.;Panagiotis Flevaris.;Lisa M Mitchell.;Shehzad Basaria.;William E Boden.;Glenn R Cunningham.;Christopher B Granger.;Mohit Khera.;Ian M Thompson.;Qiuqing Wang.;Kathy Wolski.;Deborah Davey.;Vidyasagar Kalahasti.;Nader Khan.;Michael G Miller.;Michael C Snabes.;Anna Chan.;Elena Dubcenco.;Xue Li.;Tingting Yi.;Bidan Huang.;Karol M Pencina.;Thomas G Travison.;Steven E Nissen.; .
来源: N Engl J Med. 2023年389卷2期107-117页
The cardiovascular safety of testosterone-replacement therapy in middle-aged and older men with hypogonadism has not been determined.
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