3261. Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.
作者: Jeff S Healey.;Renato D Lopes.;Christopher B Granger.;Marco Alings.;Lena Rivard.;William F McIntyre.;Dan Atar.;David H Birnie.;Giuseppe Boriani.;A John Camm.;David Conen.;Julia W Erath.;Michael R Gold.;Stefan H Hohnloser.;John Ip.;Josef Kautzner.;Valentina Kutyifa.;Cecilia Linde.;Philippe Mabo.;Georges Mairesse.;Juan Benezet Mazuecos.;Jens Cosedis Nielsen.;Francois Philippon.;Marco Proietti.;Christian Sticherling.;Jorge A Wong.;David J Wright.;Ignatius G Zarraga.;Shelagh B Coutts.;Andrew Kaplan.;Marta Pombo.;Felix Ayala-Paredes.;Lizhen Xu.;Kim Simek.;Sandra Nevills.;Rajibul Mian.;Stuart J Connolly.; .
来源: N Engl J Med. 2024年390卷2期107-117页
Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually be detected only by long-term continuous monitoring with pacemakers or defibrillators. Subclinical atrial fibrillation is associated with an increased risk of stroke by a factor of 2.5; however, treatment with oral anticoagulation is of uncertain benefit.
3262. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
作者: A Michael Lincoff.;Kirstine Brown-Frandsen.;Helen M Colhoun.;John Deanfield.;Scott S Emerson.;Sille Esbjerg.;Søren Hardt-Lindberg.;G Kees Hovingh.;Steven E Kahn.;Robert F Kushner.;Ildiko Lingvay.;Tugce K Oral.;Marie M Michelsen.;Jorge Plutzky.;Christoffer W Tornøe.;Donna H Ryan.; .
来源: N Engl J Med. 2023年389卷24期2221-2232页
Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to reduce the risk of adverse cardiovascular events in patients with diabetes. Whether semaglutide can reduce cardiovascular risk associated with overweight and obesity in the absence of diabetes is unknown.
3277. Randomized Trial of Hyperimmune Globulin for Congenital CMV Infection - 2-Year Outcomes.
作者: Brenna L Hughes.;Rebecca G Clifton.;Dwight J Rouse.;George R Saade.;Mara J Dinsmoor.;Uma M Reddy.;Robert Pass.;Donna Allard.;Gail Mallett.;Cora MacPherson.;Ronald Wapner.;Torri Metz.;William H Goodnight.;Alan T N Tita.;Maged M Costantine.;Geeta K Swamy.;Kent D Heyborne.;Edward K Chien.;Suneet P Chauhan.;Yasser Y El-Sayed.;Brian M Casey.;Samuel Parry.;Hyagriv N Simhan.;Peter G Napolitano.;George A Macones.; .
来源: N Engl J Med. 2023年389卷19期1822-1824页 |