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3034. Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis.
作者: Gregg W Stone.;Evald H Christiansen.;Ziad A Ali.;Lene N Andreasen.;Akiko Maehara.;Yousif Ahmad.;Ulf Landmesser.;Niels R Holm.
来源: Lancet. 2024年403卷10429期824-837页
Previous meta-analyses have shown reduced risks of composite adverse events with intravascular imaging-guided percutaneous coronary intervention (PCI) compared with angiography guidance alone. However, these studies have been insufficiently powered to show whether all-cause death or all myocardial infarction are reduced with intravascular imaging guidance, and most previous intravascular imaging studies were done with intravascular ultrasound rather than optical coherence tomography (OCT), a newer imaging modality. We aimed to assess the comparative performance of intravascular imaging-guided PCI and angiography-guided PCI with drug-eluting stents.
3036. Long-term efficacy of a recombinant hepatitis E vaccine in adults: 10-year results from a randomised, double-blind, placebo-controlled, phase 3 trial.
作者: Shoujie Huang.;Xuefeng Zhang.;Yingying Su.;Chunlan Zhuang.;Zimin Tang.;Xingcheng Huang.;Qi Chen.;Kongxin Zhu.;Xiaowen Hu.;Dong Ying.;Xiaohui Liu.;Hanmin Jiang.;Xia Zang.;Zhongze Wang.;Changlin Yang.;Donglin Liu.;Yijun Wang.;Quan Tang.;Wentong Shen.;Huanhuan Cao.;Huirong Pan.;Shengxiang Ge.;Yue Huang.;Ting Wu.;Zizheng Zheng.;Fengcai Zhu.;Jun Zhang.;Ningshao Xia.
来源: Lancet. 2024年403卷10429期813-823页
Hepatitis E virus (HEV) is a frequently overlooked causative agent of acute hepatitis. Evaluating the long-term durability of hepatitis E vaccine efficacy holds crucial importance.
3039. Targeted prophylactic anticoagulation based on the TRiP(cast) score in patients with lower limb immobilisation: a multicentre, stepped wedge, randomised implementation trial.
作者: Delphine Douillet.;Andrea Penaloza.;Damien Viglino.;Jean-Jacques Banihachemi.;Anmar Abboodi.;Mathilde Helderlé.;Emmanuel Montassier.;Fréderic Balen.;Christian Brice.;Saïd Laribi.;Thibault Duchenoy.;Philippe Vives.;Louis Soulat.;Nicolas Marjanovic.;Thomas Moumneh.;Dominique Savary.;Jérémie Riou.;Pierre-Marie Roy.
来源: Lancet. 2024年403卷10431期1051-1060页
Prophylactic anticoagulation in emergency department patients with lower limb trauma requiring immobilisation is controversial. The Thrombosis Risk Prediction for Patients with Cast Immobilisation-TRiP(cast)-score could identify a large subgroup of patients at low risk of venous thromboembolism for whom prophylactic anticoagulation can be safely withheld. We aimed to prospectively assess the safety of withholding anticoagulation for patients with lower limb trauma at low risk of venous thromboembolism, defined by a TRiP(cast) score of less than 7.
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