Lancet[journal] 检索结果

241. Implementation first: lessons from the TRICORDER trial in UK primary care.

作者: Sergio Cinza-Sanjurjo.;Jose R González-Juanatey.
来源: Lancet. 2026年407卷10529期653-654页

242. TRPC6 inhibition: podocyte-targeted treatment for focal segmental glomerulosclerosis?

作者: Marina Vivarelli.;Priya S Verghese.
来源: Lancet. 2026年407卷10528期549-551页

243. TRPC6 inhibition for the treatment of focal segmental glomerulosclerosis: a randomised, placebo-controlled, phase 2 trial of BI 764198.

作者: Howard Trachtman.;Matthias Kretzler.;Loreto Gesualdo.;Nicholas Cross.;Biruh Workeneh.;Jessica Kaufeld.;Björn Meijers.;Zhiming Ye.;Qinkai Chen.;Vimal K Derebail.;Monica Suet Ying Ng.;Bo Ji.;Maximilian T Lobmeyer.;Silke Retlich.;Fabia T Licarião Rocha.;Srinivasa Prasad.;Nima Soleymanlou.
来源: Lancet. 2026年407卷10528期587-598页

In focal segmental glomerulosclerosis (FSGS), transient receptor potential cation channel, subfamily C, member 6 (TRPC6) overactivity might cause podocyte loss and progressive kidney function decline. This exploratory study assessed the safety and efficacy of a novel once-daily oral selective TRPC6 inhibitor, BI 764198.

244. BCMA-CD3 T-cell engager as salvage therapy for multirefractory primary immune thrombocytopenia.

作者: Jesus Duque-Afonso.;Christoph Rummelt.;Katharina Förster.;Robert Zeiser.;Dimitrios Mougiakakos.
来源: Lancet. 2026年407卷10527期489-491页

245. The NHS 10-year plan: between aspiration and implementation.

作者: Michael Anderson.;Emma Pitchforth.;Alistair McGuire.;Elias Mossialos.
来源: Lancet. 2026年407卷10529期728-732页

246. Dan Stein.

作者: Talha Burki.
来源: Lancet. 2026年407卷10526期330页

247. Gaza: the urgent need for rigour over rhetoric - Authors' reply.

作者: Roberto De Vogli.;Jonathan Montomoli.;Ghassan Abu-Sittah.;Ilan Pappé.
来源: Lancet. 2026年407卷10526期337-338页

248. Medical ethics, accountability, and evidence during war - Author's reply.

作者: Leon Geffen.
来源: Lancet. 2026年407卷10526期336页

249. Gaza: the urgent need for rigour over rhetoric.

作者: Bénédicte Nobile.;Philippe Courtet.
来源: Lancet. 2026年407卷10526期336-337页

250. Medical ethics, accountability, and evidence during war.

作者: Zion Hagay.;Yossi Walfisch.
来源: Lancet. 2026年407卷10526期335-336页

251. Rising competition and obstacles for Internal Medicine Training applicants.

作者: Rivya Mathews.
来源: Lancet. 2026年407卷10526期334-335页

252. Syria post-Assad: where we are now and the steps ahead.

作者: Bilal Irfan.;Basel Tarab.;M Ihsan Kaadan.;Ammer Alabed.
来源: Lancet. 2026年407卷10526期333-334页

253. Offline: Dear Pope Leo XIV-please consider health.

作者: Richard Horton.
来源: Lancet. 2026年407卷10526期321页

254. Adjuvant nivolumab for resected high-risk head and neck cancer.

作者: Annette M Lim.;Danny Rischin.
来源: Lancet. 2026年407卷10526期313-314页

255. Quantifying the public health impact of physical activity.

作者: Charles E Matthews.;Pedro F Saint-Maurice.
来源: Lancet. 2026年407卷10526期310-311页

256. UHC High-Level Forum 2025: a renewed joint commitment to universal health coverage through the UHC Knowledge Hub.

作者: Katayama Satsuki.;Ueno Kenichiro.;Ajay Banga.;Tedros Adhanom Ghebreyesus.
来源: Lancet. 2026年407卷10527期476-477页

257. The SCIENCE trial: surgery or not for medial epicondyle fractures.

作者: Kathy Boutis.;Unni Narayanan.
来源: Lancet. 2026年407卷10528期548-549页

258. Global health leap: an urgent call to action.

作者: Sania Nishtar.
来源: Lancet. 2026年407卷10530期820-824页

259. A risk to child health: confusion and concern over changes to US vaccine policy.

作者: Andrew J Pollard.;Stanley Plotkin.
来源: Lancet. 2026年407卷10528期553-556页

260. Surgical fixation versus non-surgical care for children with a displaced medial epicondyle fracture of the elbow (the SCIENCE study): a multicentre, randomised controlled, superiority trial and economic evaluation.

作者: Daniel C Perry.;Juul Achten.;Alex Zimmermann.;Rebecca Kandiyali.;Duncan Appelbe.;James G Wright.;David Ferguson.;Kemble Wang.;Nichola Wilson.;Amy Moscrop.;James Mason.;Daphne Kounali.;Matthew L Costa.; .
来源: Lancet. 2026年407卷10528期577-586页

Displaced medial epicondyle fractures are among the most controversial injuries in children, with increasing trends towards surgical fixation despite little supporting evidence. Approximately half of affected children undergo surgical fixation, while others receive non-surgical care. The SCIENCE trial aimed to determine whether surgical fixation to restore the position of the bone provides superior functional outcomes and is cost-effective compared with non-surgical care.

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