2301. Hypothermic oxygenated perfusion of the donor heart in heart transplantation: the short-term outcome from a randomised, controlled, open-label, multicentre clinical trial.
作者: Filip Rega.;Guillaume Lebreton.;Marylou Para.;Sebastian Michel.;René Schramm.;Emmanuelle Begot.;Katrien Vandendriessche.;Christine Kamla.;Gino Gerosa.;Marius Berman.;Udo Boeken.;Steven Clark.;Aaron Ranasinghe.;Fabio Ius.;Alberta Forteza.;Aldina Pivodic.;Felix Hennig.;Sabina Guenther.;Andreas Zuckermann.;Christoph Knosalla.;Göran Dellgren.;Andreas Wallinder.; .
来源: Lancet. 2024年404卷10453期670-682页
Static cold storage (SCS) remains the gold standard for preserving donor hearts before transplantation but is associated with ischaemia, anaerobic metabolism, and organ injuries, leading to patient morbidity and mortality. We aimed to evaluate whether continuous, hypothermic oxygenated machine perfusion (HOPE) of the donor heart is safe and superior compared with SCS.
2302. Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands.
作者: Julia L M Bels.;Steven Thiessen.;Rob J J van Gassel.;Albertus Beishuizen.;Ashley De Bie Dekker.;Vincent Fraipont.;Stoffel Lamote.;Didier Ledoux.;Clarissa Scheeren.;Elisabeth De Waele.;Arthur R H van Zanten.;Laura Bormans-Russell.;Bas C T van Bussel.;Marlies M J Dictus.;Tom Fivez.;Ingeborg Harks.;Iwan C C van der Horst.;Joop Jonckheer.;Hugues Marechal.;Paul B Massion.;Ingrid Meex.;Michelle C Paulus.;Martin Rinket.;Susanne van Santen.;Katrien Tartaglia.;Adam M Deane.;Frieda Demuydt.;Zudin Puthucheary.;Lilian C M Vloet.;Peter J M Weijs.;Sander M J van Kuijk.;Marcel C G van de Poll.;Dieter Mesotten.; .
来源: Lancet. 2024年404卷10453期659-669页
Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes in critically ill patients who were mechanically ventilated compared with standard enteral protein provision (ie, 1·3 g/kg per day).
2320. Nature-based solutions are essential for climate and health action.
作者: Neil M Vora.;Shweta Narayan.;Aggrey Aluso.;Camila I Donatti.;Omnia El Omrani.;Lee Hannah.;Jemilah Mahmood.;Nicaise Ndembi.;Mariana M Vale.;Elizabeth Willetts.
来源: Lancet. 2024年404卷10456期913-915页 |