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2143. Addressing Sex Disparities in Lung Cancer Screening Eligibility: USPSTF vs PLCOm2012 Criteria.
作者: Mary M Pasquinelli.;Martin C Tammemägi.;Kevin L Kovitz.;Marianne L Durham.;Zanë Deliu.;Arielle Guzman.;Kayleigh Rygalski.;Li Liu.;Matthew Koshy.;Patricia Finn.;Lawrence E Feldman.
来源: Chest. 2022年161卷1期248-256页
Lung cancer is the leading cause of cancer death in women in the United States. Prospective randomized lung screening trials suggest a greater lung cancer mortality benefit from screening women compared with men.
2144. Presenting Features and Clinical Course of Chronic Nitrofurantoin-Induced Lung Toxicity.
作者: Vasilios Tzilas.;Antonios Charokopos.;Lykourgos Kolilekas.;Effrosyni Manali.;Spyridon Papiris.;Jay H Ryu.;Demosthenes Bouros.
来源: Chest. 2022年161卷3期748-752页 2145. An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function.
作者: Joshua Keefe.;Chen Yao.;Shih-Jen Hwang.;Paul Courchesne.;Gha Young Lee.;Josée Dupuis.;Joseph P Mizgerd.;George O'Connor.;George R Washko.;Michael H Cho.;Edwin K Silverman.;Daniel Levy.
来源: Chest. 2022年161卷1期76-84页
There are few clinically useful circulating biomarkers of lung function and lung disease. We hypothesized that genome-wide association studies (GWAS) of circulating proteins in conjunction with GWAS of pulmonary traits represents a clinically relevant approach to identifying causal proteins and therapeutically useful insights into mechanisms related to lung function and disease.
2146. Detection and Early Referral of Patients With Interstitial Lung Abnormalities: An Expert Survey Initiative.
作者: Gary M Hunninghake.;Jonathan G Goldin.;Michael A Kadoch.;Jonathan A Kropski.;Ivan O Rosas.;Athol U Wells.;Ruchi Yadav.;Howard M Lazarus.;Fereidoun G Abtin.;Tamera J Corte.;Joao A de Andrade.;Kerri A Johannson.;Martin R Kolb.;David A Lynch.;Justin M Oldham.;Paolo Spagnolo.;Mary E Strek.;Sara Tomassetti.;George R Washko.;Eric S White.; .
来源: Chest. 2022年161卷2期470-482页
Interstitial lung abnormalities (ILA) may represent undiagnosed early-stage or subclinical interstitial lung disease (ILD). ILA are often observed incidentally in patients who subsequently develop clinically overt ILD. There is limited information on consensus definitions for, and the appropriate evaluation of, ILA. Early recognition of patients with ILD remains challenging, yet critically important. Expert consensus could inform early recognition and referral.
2147. Prolonged Prehospital Time Is a Risk Factor for Pneumonia in Trauma (the PRE-TRIP Study): A Retrospective Analysis of the United States National Trauma Data Bank.
作者: Lee E Morrow.;Nikhil Jagan.;Ryan W Walters.;Robert W Plambeck.;Merrie Oshiro.;Mark A Malesker.
来源: Chest. 2022年161卷1期85-96页
Although multiple risk factors for development of pneumonia in patients with trauma sustained in a motor vehicle accident have been studied, the effect of prehospital time on pneumonia incidence post-trauma is unknown.
2148. Antibiotic Timing and Progression to Septic Shock Among Patients in the ED With Suspected Infection.
作者: Roshan Bisarya.;Xing Song.;John Salle.;Mei Liu.;Anurag Patel.;Steven Q Simpson.
来源: Chest. 2022年161卷1期112-120页
Recent medical society opinions have questioned the use of early antimicrobials in patients with sepsis, but without septic shock.
2149. SICQ Coping and the Health-Related Quality of Life and Recovery of Critically Ill ICU Patients: A Prospective Cohort Study.
作者: Edwin J Boezeman.;José G M Hofhuis.;Christopher E Cox.;Reinout E de Vries.;Peter E Spronk.
来源: Chest. 2022年161卷1期130-139页
The coping styles of the Sickness Insight in Coping Questionnaire (SICQ; positivism, redefinition, toughness, fighting spirit, nonacceptance) may affect the health and recovery of hospitalized critically ill patients.
2150. The Usefulness of the Rapid Shallow Breathing Index in Predicting Successful Extubation: A Systematic Review and Meta-analysis.
作者: Vatsal Trivedi.;Dipayan Chaudhuri.;Rehman Jinah.;Joshua Piticaru.;Arnav Agarwal.;Kuan Liu.;Eric McArthur.;Michael C Sklar.;Jan O Friedrich.;Bram Rochwerg.;Karen E A Burns.
来源: Chest. 2022年161卷1期97-111页
Clinicians use several measures to ascertain whether individual patients will tolerate liberation from mechanical ventilation, including the rapid shallow breathing index (RSBI).
2151. Early Tracheostomy for Managing ICU Capacity During the COVID-19 Outbreak: A Propensity-Matched Cohort Study.
作者: Gonzalo Hernandez.;Francisco Javier Ramos.;José Manuel Añon.;Ramón Ortiz.;Laura Colinas.;Joan Ramón Masclans.;Candelaria De Haro.;Alfonso Ortega.;Oscar Peñuelas.;María Del Mar Cruz-Delgado.;Alfonso Canabal.;Oriol Plans.;Concepción Vaquero.;Gemma Rialp.;Federico Gordo.;Amanda Lesmes.;María Martinez.;Juan Carlos Figueira.;Alejandro Gomez-Carranza.;Rocio Corrales.;Andrea Castellvi.;Beatriz Castiñeiras.;Fernando Frutos-Vivar.;Jorge Prada.;Raul De Pablo.;Antonio Naharro.;Juan Carlos Montejo.;Claudia Diaz.;Alfonso Santos-Peral.;Rebeca Padilla.;Judith Marin-Corral.;Carmen Rodriguez-Solis.;Juan Antonio Sanchez-Giralt.;Jorge Jimenez.;Rafael Cuena.;Santiago Perez-Hoyos.;Oriol Roca.
来源: Chest. 2022年161卷1期121-129页
During the first wave of the COVID-19 pandemic, shortages of ventilators and ICU beds overwhelmed health care systems. Whether early tracheostomy reduces the duration of mechanical ventilation and ICU stay is controversial.
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