2061. Living, Rapid Reviews in a Rapidly Evolving World.
In their article, Holmer and colleagues reported the final update of a living review that examined the duration of IgG antibody response, the role of previous SARS-CoV-2 infection to prevent reinfection, and the role of antibodies in protection from reinfection. The editorialist discusses the challenge of living reviews as new evidence emerges and the relevant clinical questions evolve.
2064. Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 1).
作者: Amir Qaseem.;Jennifer Yost.;Matthew C Miller.;Rebecca Andrews.;Janet A Jokela.;Mary Ann Forciea.;George M Abraham.;Linda L Humphrey.; .;Rachael A Lee.;Mark P Tschanz.;Itziar Etxeandia-Ikobaltzeta.;Curtis Harrod.;Tatyana Shamliyan.;Karla Umana.
来源: Ann Intern Med. 2023年176卷1期115-124页
Strategies to manage COVID-19 in the outpatient setting continue to evolve as new data emerge on SARS-CoV-2 variants and the availability of newer treatments. The Scientific Medical Policy Committee (SMPC) of the American College of Physicians (ACP) developed these living, rapid practice points to summarize the best available evidence on the treatment of adults with confirmed COVID-19 in an outpatient setting. These practice points do not evaluate COVID-19 treatments in the inpatient setting or adjunctive COVID-19 treatments in the outpatient setting.
2065. Major Update 2: Antibody Response and Risk for Reinfection After SARS-CoV-2 Infection-Final Update of a Living, Rapid Review.
作者: Haley K Holmer.;Katherine Mackey.;Celia V Fiordalisi.;Mark Helfand.
来源: Ann Intern Med. 2023年176卷1期85-91页
The durability of the antibody response after SARS-CoV-2 infection and the role of antibodies in protection against reinfection are unclear.
2066. Ongoing Need for Clinical Trials and Contemporary End Points for Outpatient COVID-19.
The American College of Physicians presents recommendations for the outpatient treatment of COVID-19 based on Sommer and colleagues' systematic review. The editorialists commend the authors of the recommendations and review for trying to summarize the rapidly evolving literature into clear practice points and discuss the challenges of continually updating reviews and associated recommendations as new evidence emerges and relevant outcomes evolve.
2067. Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Review for the American College of Physicians.
作者: Isolde Sommer.;Andreea Dobrescu.;Dominic Ledinger.;Isabel Moser.;Kylie Thaler.;Emma Persad.;Martin Fangmeyer.;Robert Emprechtinger.;Irma Klerings.;Gerald Gartlehner.
来源: Ann Intern Med. 2023年176卷1期92-104页
Clinicians and patients want to know the benefits and harms of outpatient treatment options for SARS-CoV-2 infection.
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